Fusion in the fast lane

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Fig. 1: Confocal microscopy images of lipid vesicles containing two different fluorescent dyes: (a) Two vesicles before fusion (equatorial section) (b) Vesicles fused by applying a short electric pulse and (c) Three-dimensional image of a two-domain ...
Fig. 1: Confocal microscopy images of lipid vesicles containing two different fluorescent dyes: (a) Two vesicles before fusion (equatorial section); (b) Vesicles fused by applying a short electric pulse; and (c) Three-dimensional image of a two-domain vesicle produced by fusion of two membranes with different composition. Credit: Image: Max Planck Institute of Colloids and Interfaces
Using fast digital imaging, scientists from the Max Planck Institute of Colloids and Interfaces in Potsdam, Germany, together with researchers from College de France, have succeeded in developing two different protocols by which one can initiate the fusion process in a controlled manner and observe the subsequent fusion dynamics with a temporal resolution in the microsecond regime.


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