Regulating the nuclear architecture of the cell

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The nucleolus (dark blue) resides within the cell nucleus surrounded by heterochromatin. Berkeley Lab researchers have discovered the molecular pathways that regulate its organization. Credit: Lawrence Berkeley National Laboratory
The nucleolus (dark blue) resides within the cell nucleus, surrounded by heterochromatin. Berkeley Lab researchers have discovered the molecular pathways that regulate its organization. Credit: Lawrence Berkeley National Laboratory

An organelle called the nucleolus resides deep within the cell nucleus and performs one of the cell's most critical functions: it manufactures ribosomes, the molecular machines that convert the genetic information carried by messenger RNA into proteins that do the work of life.


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