Identification of carbon dioxide receptors in insects may help fight infectious disease

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Carbon dioxide-sensitive neurons expressing Gr21a (green) and Gr63a (red) proteins that together (white) are necessary for carbon dioxide detection. The neurons target a specific region of the fly brain which is dedicated to processing the smell of c ...
Carbon dioxide-sensitive neurons expressing Gr21a (green) and Gr63a (red), proteins that together (white) are necessary for carbon dioxide detection. The neurons target a specific region of the fly brain, which is dedicated to processing the smell of carbon dioxide. Credit: Vosshall Laboratory

Mosquitoes don’t mind morning breath. They use the carbon dioxide people exhale as a way to identify a potential food source. But when they bite, they can pass on a number of dangerous infectious diseases, such as malaria, yellow fever, and West Nile encephalitis. Now, reporting in today’s advance online publication in Nature, Leslie Vosshall’s laboratory at Rockefeller University has identified the two molecular receptors in fruit flies that help these insects detect carbon dioxide.


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