A novel hMSH2 gene mutation in colorectal cancer patients?

About 20% CRC patients have a genetic component and HNPCC is the most common autosomal dominant hereditary syndrome. Some Chinese HNPCC pedigrees were recently reported in the January 14, 2008 issue of the World Journal of Gastroenterology because of their great significance for hereditary CRC. This article will undoubtedly bring comfort to many families.