Allergic response tied to lipid molecules in cell membrane

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Nanostructural changes in the plasma membrane occur upon antigen stimulation. Image courtesy of Erin Sheets Penn State
Nanostructural changes in the plasma membrane occur upon antigen stimulation. Image courtesy of Erin Sheets, Penn State

A team of Penn State University researchers is the first to demonstrate that lipid molecules in cell membranes participate in mammals' reactions to allergens in a living cell. The finding will help scientists better understand how allergy symptoms are triggered, and could contribute to the creation of improved drugs to treat them. The work will be reported in the 14 March issue of the Journal of Biological Chemistry.


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