Mini-Donut Catches Chloride Ions

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When traditionally weak C-H hydrogen bonds are preorganized in a shape-persistent macrocycle a strong affinity for chloride ions emerges. This discovery arises from the dual use of click chemistry for efficient macrocyclization and the favorable ster ...
When traditionally weak C-H hydrogen bonds are preorganized in a shape-persistent macrocycle, a strong affinity for chloride ions emerges. This discovery arises from the dual use of click chemistry for efficient macrocyclization and the favorable steric properties of the resulting 1,2,3-triazoles. Credit: (C) Wiley-VCH 2008

Ions—charged atoms or molecules—play an important role in nature, in our bodies as well as for science and technology. It is often necessary to trap, remove, mask, stabilize, or transport ions, whether in the body or the lab. With positively charged metal ions, this goal is often achieved with chelate ligands, organic molecules that tightly grab hold of the ions.


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All News summaries for March 11, 2008