'Nanodrop' Test Tubes Created with a Flip of a Switch

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With the flip of a switch: Nanodrop test tubes are created by an electronic switch that causes a micropipette to jerk back and leave behind a droplet less that 1 micron in diameter for study. Credit: NIST
With the flip of a switch: Nanodrop "test tubes" are created by an electronic switch that causes a micropipette to jerk back and leave behind a droplet less that 1 micron in diameter for study. Credit: NIST

Researchers at the National Institute of Standards and Technology have demonstrated a new device that creates nanodroplet “test tubes” for studying individual proteins under conditions that mimic the crowded confines of a living cell. “By confining individual proteins in nanodroplets of water, researchers can directly observe the dynamics and structural changes of these biomolecules,” says physicist Lori Goldner, a coauthor of the paper published in Langmuir.


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