Study calls for action on heart risks from certain anti-cancer drugs

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Conceptual representation of a constellation of factors that synergize with cardiotoxicity induced by a known cardiotoxic drug and make cardiac events occur at lower than expected cumulative doses of that drug. Credit: Courtesy of P. Menna E. Salvato ...
Conceptual representation of a constellation of factors that synergize with cardiotoxicity induced by a known cardiotoxic drug and make cardiac events occur at lower than expected cumulative doses of that drug. Credit: Courtesy of P. Menna, E. Salvatorelli and G. Minotti

Heart damage from certain anti-cancer drugs no longer should be regarded as a rare or relatively unimportant complication, scientists in Italy have concluded in a new overview of research on the cardiotoxicity of anti-cancer drugs. Their review, scheduled for the May 19 issue of ACS’ monthly journal, Chemical Research in Toxicology, recommends that drug regulatory agencies, physicians, and toxicologists join in a focused research effort to combat the problem.


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