Stripes key to nanoparticle drug delivery

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MIT researchers have created striped nanoparticles capable of entering a cell without rupturing it. In the background of this cartoon are cells that have taken up nanoparticles carrying fluorescent imaging agents. Image courtesy: Francesco Stellacci ...
MIT researchers have created 'striped' nanoparticles capable of entering a cell without rupturing it. In the background of this cartoon are cells that have taken up nanoparticles carrying fluorescent imaging agents. Image courtesy: Francesco Stellacci, Darrell Irvine and colleagues, MIT

In work that could at the same time impact the delivery of drugs and explain a biological mystery, MIT engineers have created the first synthetic nanoparticles that can penetrate a cell without poking a hole in its protective membrane and killing it. The key to their approach? Stripes.


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