Team finds key mechanism of DDT resistance in malarial mosquitoes

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Biochemistry professor Mary Schuler and postdoctoral researcher Sanjeewa Rupasinghe used molecular modeling techniques to identify a protein that can metabolize DDT. Credit: Photo by L. Brian Stauffer U. of I. News Bureau
Biochemistry professor Mary Schuler and postdoctoral researcher Sanjeewa Rupasinghe used molecular modeling techniques to identify a protein that can metabolize DDT. Credit: Photo by L. Brian Stauffer, U. of I. News Bureau

University of Illinois researchers have identified a key detoxifying protein in Anopheles mosquitoes that metabolizes DDT, a synthetic insecticide used since World War II to control the mosquitoes that spread malaria.


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