Stem Cell Chicken and Egg Debate Moves to Unlikely Arena: The Testes

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The hub cells found at the tip of Drosophila testis are outlined with DE-cadherin (shown in red). A lineage tracing strategy which marks somatic stem cells and their offspring with green flourescent protein revealed that these cells are direct descen ...
The hub cells found at the tip of Drosophila testis are outlined with DE-cadherin (shown in red). A lineage tracing strategy, which marks somatic stem cells and their offspring with green flourescent protein, revealed that these cells are direct descendants of somatic stem cells. Image: Courtesy of Justin Voog, Salk Institute for Biological Studies
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Logic says it has to be the niche. As air and water preceded life, so the niche, that hospitable environment that shelters adult stem cells in many tissues and provides factors necessary to keep them young and vital, must have emerged before its stem cell dependents.


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