Switchable fluorescent proteins - able to switch themselves reversibly back-and-forth between an "on" and "off" state - have been known for only a few years. However, they already hold promise for a large number of novel applications, from cellular biology to data storage. Cell biologists, X-Ray crystallographers, photobiophysicists, and computer-biophysicists from Goettingen have worked together on a project uncovering the molecular mechanism by which a fluorescent protein becomes switched.
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