Temperature-Sensitive Nanoparticles Open New Avenues for Drug Delivery

Many types of nanoparticles can cross the cell membrane and deliver their therapeutic payload into tumor cells. In some instances, however, nanoparticles can become trapped inside endosomes, distinct compartments within a cell in which enzymes can break down some anticancer agents. As a result, anticancer genes or drugs that must reach the nucleus in order to kill the cell may never reach their intended destination intact.