Nanotextured implant materials: blending in, not fighting back

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The faster endothelial cells (green) form a single smooth layer the less chance exposed metal will provoke an immune response. Samples examined after 1 3 and 5 days (left to right) show better coverage on nanotextured titanium (bottom row) than on co ...
The faster endothelial cells (green) form a single smooth layer, the less chance exposed metal will provoke an immune response. Samples examined after 1, 3 and 5 days (left to right) show better coverage on nanotextured titanium (bottom row) than on conventional microstructured titanium. Credit: Image: Thomas Webster

Biomedical engineers are constantly coming up with ways to repair the human body, replacing defective and worn out parts with plastic, titanium, and ceramic substitutes – but the body does not always accept such substitutes seamlessly. Engineers from Brown and Purdue universities have found that simply changing the surface texture of implants can dramatically change the way cells colonize a wide variety of materials.


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