First demonstration of new hair follicle generation in an animal model

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Growth of regenerated hair follicles over 45 days. Arrows indicate hair shaft. The bulge is the area from which new hair shafts arise. The regenerated follicles possess normal stem cells and function normally by producing a hair shaft and cycling thr ...
Growth of regenerated hair follicles over 45 days. Arrows indicate hair shaft. The bulge is the area from which new hair shafts arise. The regenerated follicles possess normal stem cells and function normally by producing a hair shaft and cycling through growth phases. Credit: George Cotsarelis, MD, University of Pennsylvania School of Medicine; Nature

Researchers at the University of Pennsylvania School of Medicine have found that hair follicles in adult mice regenerate by re-awakening genes once active only in developing embryos. These findings provide unequivocal evidence for the first time that, like other animals such as newts and salamanders, mammals have the power to regenerate. These findings are published in the May 17 issue of Nature.


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