Scientists develop method to track immune system enzyme in live animals

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In this picture of intestinal villi from one of the new mouse strains plasma cells are tagged with yellow (green-appearing) fluorescent protein. Credit: National Institute of Arthritis and Musculoskeletal and Skin Diseases
In this picture of intestinal villi from one of the new mouse strains, plasma cells are tagged with yellow (green-appearing) fluorescent protein. Credit: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Scientists supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health have created two mouse strains that will permit researchers to trace, in a live animal, the activity of an enzyme believed to play a crucial role both in the normal immune response as well as autoimmunity and B cell tumor development. Their report appears in the Journal of Experimental Medicine.


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