http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Breast cancer patients face many horrors, including those that arise when fighting the cancer itself. Medications given during chemotherapy can have wicked side effects, including vomiting, dizziness, anemia and hair loss. These side effects occur because medications released into the body target healthy cells as well as tumor cells. http://www.physorg.com/news155940166.html Nanotechnology Tue, 10 Mar 2009 21:43:00 EST news155940166 A glass of milk, a gallon of paint, and a bottle of salad dressing all look to the naked eye like liquids. But when viewed under a microscope these everyday liquids, called "colloids," actually contain small globules or particles that stay suspended in solution. http://www.physorg.com/news131890799.html Nanotechnology Thu, 05 Jun 2008 13:19:59 EST news131890799 Investigators at Northwestern University have found that packing small interfering RNA (siRNA) molecules onto the surface of a gold nanoparticle can protect siRNAs from degradation and increase their ability to regulate genes involved in cancer. As a result of this discovery, cancer researchers have at their disposal a relatively straightforward method of delivering these potent gene-regulating agents into targeted cells. http://www.physorg.com/news154627849.html Nanotechnology Mon, 23 Feb 2009 16:11:37 EST news154627849 (PhysOrg.com) -- One of the key steps in the development of any drug or imaging agent intended for human use is measurement of the adsorption, metabolism, and excretion of the drug. Quantifying this collection of pharmacological properties, known as ADME, is a challenging and time-consuming process that is even more difficult when the drug or imaging agent includes a nanoparticle as one of its components. But by taking advantage of the magnetic properties of one kind of nanoparticle, a team of investigators at Washington University in St. Louis has demonstrated that they can measure ADME quickly using magnetic resonance imaging (MRI). http://www.physorg.com/news149265429.html Nanotechnology Tue, 23 Dec 2008 14:37:09 EST news149265429 Researchers at the Harvard School of Engineering and Applied Sciences (SEAS) have demonstrated experimentally and theoretically that the surface plasmon resonances of metal nanoparticles in a periodic array can have considerably narrower spectral widths than those of isolated metal nanoparticles. Further, as the optical fields are significantly more intense in a periodic array, the method could improve the sensitivity of detecting molecules at low concentrations. http://www.physorg.com/news145878081.html Physics Fri, 14 Nov 2008 09:41:21 EST news145878081 (PhysOrg.com) -- Adah Almutairi, Ph.D., assistant professor in the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California, San Diego, is first author of a paper recently published in the Proceedings of the National Academy of Sciences (PNAS.) The work of Almutairi and her former colleagues at UC Berkeley, along with researchers from the Washington University School of Medicine, describes a novel synthetic nanoparticle developed for noninvasive imaging of angiogenesis. http://www.physorg.com/news151260231.html Nanotechnology Thu, 15 Jan 2009 16:43:51 EST news151260231 (PhysOrg.com) -- Using a nanoparticle from corn, a Purdue University scientist has found a way to lengthen the shelf life of many food products and sustain their health benefits. http://www.physorg.com/news179507163.html Nanotechnology Tue, 08 Dec 2009 15:08:43 EST news179507163 (PhysOrg.com) -- Cisplatin is one of the most powerful and effective drugs for treating a wide variety of cancers, but serious side effects ultimately limit the drug's use and effectiveness. Now, however, researchers have developed a nanoparticulate formulation of cisplatin that may be able to eliminate or reduce platinum-associated toxicity while boosting cisplatin's tumor-killing activity. http://www.physorg.com/news176060990.html Nanotechnology Thu, 29 Oct 2009 18:50:19 EST news176060990 (PhysOrg.com) -- We cannot live without it; yet too much of it causes damage: oxygen is a critical component of many physiological and pathological processes in living cells. Oxygen deficiency in tissues is thus related to tumor growth, retinal damage from diabetes, and rheumatoid arthritis. It is thus important to determine the oxygen content of cells and tissues, which is a challenge to scientists. http://www.physorg.com/news157373939.html Nanotechnology Fri, 27 Mar 2009 12:00:45 EST news157373939 Dr. Esther Chang describes the most recent developments in human trials of the first systemic, non-viral, tumor-targeted, nanoparticle method designed to restore normal gene function to tumor cells while completely bypassing normal tissue April 21 at an American Association of Anatomists (AAA) scientific session at Experimental Biology 2009 in New Orleans. http://www.physorg.com/news159466748.html Nanotechnology Mon, 20 Apr 2009 17:19:30 EST news159466748 In a finding that could help speed the understanding of diseases ranging from cancer to osteoporosis, researchers in Utah are reporting development of a new microscope technique that uses `silver nanoparticle` mirrors to reveal hidden details inside bones, cancer cells, and other biological structures. The method also can help identify structural damage in a wide variety of materials, including carbon-fiber plastics used in airplanes, the researchers say. http://www.physorg.com/news154894368.html Nanotechnology Thu, 26 Feb 2009 18:13:19 EST news154894368 Arsenic trioxide has a long history as a potent human poison, but it also has proven valuable as one of the primary treatment options for acute promyelocytic leukemia. Efforts to use arsenic trioxide to treat other types of cancer are under way, but clinical trials are revealing that the extreme toxicity of this material is likely to limit its utility as a broad-spectrum anticancer agent. http://www.physorg.com/news167412238.html Nanotechnology Wed, 22 Jul 2009 13:30:01 EST news167412238 When you make a new material on a nanoscale how can you see what you have made? A team lead by a Biotechnology and Biological Sciences research Council (BBSRC) fellow has made a significant step toward overcoming this major challenge faced by nanotechnology scientists. http://www.physorg.com/news137837953.html Nanotechnology Wed, 13 Aug 2008 09:19:13 EST news137837953 (PhysOrg.com) -- Cancer cells, like bacteria, can develop resistance to drug therapy, leading to relapse of disease. One approach showing promise in overcoming multidrug resistance in tumors is to combine two different anticancer agents in one nanoscale construct, providing a one-two punch that can prove lethal to such resistant cells. An example of this approach appears in the journal Small. http://www.physorg.com/news176541150.html Nanotechnology Wed, 04 Nov 2009 07:12:55 EST news176541150 Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to 24 months, according to a report in Cancer Research, a journal of the American Association for Cancer Research. http://www.physorg.com/news168149704.html Medicine & Health Thu, 30 Jul 2009 05:21:34 EST news168149704