http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. A gene associated with a rare form of progressive deafness in males has been identified by an international team of researchers funded by the National Institute on Deafness and Other Communication Disorders. The gene, PRPS1, appears to be crucial in inner ear development and maintenance. The findings are published in the Dec. 17 early online issue of the American Journal of Human Genetics. http://www.physorg.com/news180277698.html Medicine & Health Thu, 17 Dec 2009 13:20:05 EST news180277698 A gene involved in some forms of intellectual disability has been identified by scientists at the Centre for Addiction and Mental Health (CAMH), as published this month in The American Journal of Human Genetics. The gene is called TRAPPC9. http://www.physorg.com/news180101256.html Medicine & Health Tue, 15 Dec 2009 12:30:04 EST news180101256 Researchers have discovered a new explanation for differences in the severity of mental illness in males. The more excess copies of a certain gene, the more serious the handicap. The genetic defect is situated on the X-chromosome; and it is suspected that it is the amount of copies of the GDI1 gene that is responsible. The results are being published in the American Journal of Human Genetics, and are the result of work by the group of Guy Froyen connected to VIB, a life sciences research institute in Flanders, Belgium at the University of Leuven, in close collaboration with Hilde Van Esch of the Center for Human Genetics (University Hospital Leuven) and colleagues in Germany and Spain. http://www.physorg.com/news179673953.html Medicine & Health Thu, 10 Dec 2009 13:31:58 EST news179673953 The first genetic historical map of the Han Chinese, the largest ethnic population in the world, as they migrated from south to north over evolutionary time. was published online today by the American Journal of Human Genetics by scientists at the Genome Institute of Singapore (GIS). http://www.physorg.com/news178382161.html Medicine & Health Wed, 25 Nov 2009 14:36:36 EST news178382161 A new study uses a creative structure-based remodeling strategy to design a therapeutic protein that exhibits significant advantages over currently available treatments for a rare disease that often leads to cardiac and renal failure. The research, published by Cell Press on October 22nd in the American Journal of Human Genetics, describes a new and highly promising candidate for enzyme replacement therapy (ERT) for Fabry disease. http://www.physorg.com/news175436202.html Medicine & Health Thu, 22 Oct 2009 13:30:06 EST news175436202 (PhysOrg.com) -- A genetic mutation found in four children born with multiple abnormalities may provide insight into potential treatments for newborn lung distress and chronic obstructive pulmonary disease (COPD). http://www.physorg.com/news174827807.html Medicine & Health Thu, 15 Oct 2009 12:50:01 EST news174827807 Two recent studies by Dartmouth researchers use individual genetic data to reveal the powers and limits of our current understanding of how the genome influences human health and what genes can reveal about the ancestry of the people of New Hampshire. http://www.physorg.com/news172231224.html Medicine & Health Tue, 15 Sep 2009 11:01:25 EST news172231224 (PhysOrg.com) -- In the week that the University of Leicester celebrates the 25th anniversary of the discovery of DNA fingerprinting (Thursday September 10) new findings from the world-renowned University of Leicester Department of Genetics reveal for the first time that the male and female do truly communicate -- at least at the fundamental genetic level. http://www.physorg.com/news171707200.html Medicine & Health Wed, 09 Sep 2009 19:00:01 EST news171707200 A team led by scientists from The Scripps Research Institute has discovered a genetic cause of progressive hearing loss. The findings will help scientists better understand the nature of age-related decline in hearing and may lead to new therapies to prevent or treat the condition. http://www.physorg.com/news171203447.html Medicine & Health Thu, 03 Sep 2009 13:40:02 EST news171203447 New research reveals that a simple laboratory assay detects a genetic variation in host response to bacterial infection that is associated with an increased susceptibility for inflammatory disease. The study, published by Cell Press online on August 6th in the American Journal of Human Genetics, also provides fascinating insight into the link between evolution and the ability to ward off pathogens. http://www.physorg.com/news168792564.html Medicine & Health Thu, 06 Aug 2009 18:50:01 EST news168792564 Practice, practice, practice might get you to Carnegie Hall, but for aspiring musicians, there's new evidence that genes may influence one's ability to get there, as well. http://www.physorg.com/news165772613.html Medicine & Health Thu, 02 Jul 2009 16:57:13 EST news165772613 A rare, deadly developmental disorder of the lungs called alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) that usually kills the infants born with it within the first month of life results from deletions or mutations in the FOXF1 transcription factor gene, said a consortium of researchers led by Baylor College of Medicine in a report that appears in the American Journal of Human Genetics. http://www.physorg.com/news163341976.html Medicine & Health Thu, 04 Jun 2009 13:46:48 EST news163341976 New research provides exciting genetic insight into a rare syndrome that first appeared in the medical literature in the mid 1800s with the case of Julia Pastrana, the world's most notorious bearded lady. The study, published by Cell Press in the May 21st issue of the American Journal of Human Genetics, reveals intriguing molecular clues about the pathogenesis of this mysterious condition that has captured the attention of the public since the Middle Ages. http://www.physorg.com/news162129462.html Medicine & Health Thu, 21 May 2009 12:58:57 EST news162129462 (PhysOrg.com) -- The first specific genetic mutation which can cause a potentially serious facial disfigurement has been identified by researchers at Oxford University. The finding, published online in the American Journal of Human Genetics, offers the promise of improved genetic counselling for parents at risk. http://www.physorg.com/news161612123.html Medicine & Health Fri, 15 May 2009 13:17:12 EST news161612123 (PhysOrg.com) -- Through sophisticated statistical analyses and advanced computer simulations, researchers are learning more about the genomic patterns of human population structure around the world. http://www.physorg.com/news161528365.html Medicine & Health Thu, 14 May 2009 14:00:01 EST news161528365 For the first time, scientists have discovered a single gene defect that causes thoracic aortic aneurysms and dissections as well as early onset coronary artery disease, ischemic stroke and Moyamoya disease. The research is led by scientists at The University of Texas Health Science Center at Houston. http://www.physorg.com/news160405578.html Medicine & Health Fri, 01 May 2009 14:07:00 EST news160405578 University of Utah researchers have identified a region of the human genome that may contribute to the development of pelvic floor disorders such as pelvic organ prolapse and stress urinary incontinence, according to a study published this week in the American Journal of Human Genetics. http://www.physorg.com/news159712467.html Medicine & Health Thu, 23 Apr 2009 13:34:50 EST news159712467 (PhysOrg.com) -- After 12 years of searching, UCLA scientists have tracked down the first known gene mutation responsible for a heartbreaking disorder that kills newborn babies. Published in the April 1 online edition of the American Journal of Human Genetics, their findings will allow for earlier testing of embryos at risk for the disease. http://www.physorg.com/news157807581.html Medicine & Health Wed, 01 Apr 2009 12:27:11 EST news157807581 Discovering the different genes that contribute to a complex disease is like searching in the proverbial haystack for an unknown number of needles--some much smaller than others, often blending into the background, and many of them widely separated from each other. But if some needles are linked to each other by fine threads, you might pull out clumps of them together. http://www.physorg.com/news154876287.html Medicine & Health Thu, 26 Feb 2009 13:12:06 EST news154876287 1 in 200 of our human genes can be inactivated with no detectable effect on our health. A study by Wellcome Trust Sanger Institute scientists raises new questions about the effects of gene loss on our wellbeing and evolution. http://www.physorg.com/news153059061.html Medicine & Health Thu, 05 Feb 2009 12:25:13 EST news153059061 Researchers at the Johns Hopkins University School of Medicine are one gene closer to understanding schizophrenia and related disorders. Reporting in the Jan. 9 issue of the American Journal of Human Genetics, the team describes how a variation in the neuregulin 3 gene influences delusions associated with schizophrenia. http://www.physorg.com/news152897163.html Medicine & Health Tue, 03 Feb 2009 15:27:34 EST news152897163 Mutation of a gene that helps proteins migrate in and out of the cell's genetic command center - the nucleus - puts some families at higher risk for the degenerative brain disease acute necrotizing encephalopathy (ANE). http://www.physorg.com/news150468352.html Medicine & Health Tue, 06 Jan 2009 12:45:52 EST news150468352 Scientists have new information about the complex genetic signature associated with Alzheimer's disease, the leading cause of cognitive decline and dementia in the elderly. The research, published by Cell Press in the January issue of the American Journal of Human Genetics, uses a powerful, high-resolution analysis to look for genes associated with this devastating neurodegenerative disorder. http://www.physorg.com/news149947901.html Medicine & Health Wed, 31 Dec 2008 12:11:41 EST news149947901