http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. How a specific gene within the pancreas affects secretion of insulin has been discovered by researchers from the Hebrew University of Jerusalem, in collaboration with Japanese and American universities. Their work opens the way for a new understanding of possible paths to battle diabetes and diabetes-related health problems, which are on the rise all over the world. http://www.physorg.com/news177244751.html Biology Thu, 12 Nov 2009 10:50:01 EST news177244751 St. Jude Children's Research Hospital investigators have discovered how destructive immune cells gain access to insulin-producing cells and help cause diabetes. http://www.physorg.com/news174223628.html Medicine & Health Thu, 08 Oct 2009 12:40:01 EST news174223628 One of the biggest mysteries about diabetes is why specialized cells in the pancreas stop secreting insulin, which the body needs in order to store glucose from food. A team from the Children's Hospital of Eastern Ontario (CHEO) Research Institute has identified a protein that inhibits insulin production in mice - work that offers a new way of understanding, and perhaps of one day treating, both Type 1 and Type 2 diabetes. http://www.physorg.com/news174138674.html Chemistry Wed, 07 Oct 2009 12:52:34 EST news174138674 By investigating a rare and severe form of diabetes in children, University of Iowa researchers have discovered a new molecular mechanism that regulates specialized pancreatic cells and insulin secretion. The mechanism involves a protein called ankyrin, which UI researchers previously linked to potentially fatal human heart arrhythmias. http://www.physorg.com/news171634645.html Medicine & Health Tue, 08 Sep 2009 13:17:54 EST news171634645 People diagnosed with type 2 diabetes often resist taking insulin because they fear gaining weight, developing low blood sugar and seeing their quality of life decline. http://www.physorg.com/news169187921.html Medicine & Health Tue, 11 Aug 2009 06:10:01 EST news169187921 In findings that add to the prospects of regenerating insulin-producing cells in people with type 1 diabetes, researchers in Europe -- co-funded by the Juvenile Diabetes Research Foundation -- have shown that insulin-producing beta cells can be derived from non-insulin-producing cells in the pancreas. http://www.physorg.com/news168799882.html Medicine & Health Thu, 06 Aug 2009 17:54:39 EST news168799882 Researchers have found a way in mice to convert another type of pancreas cell into the critical insulin-producing beta cells that are lost in those with type I diabetes. The secret ingredient is a single transcription factor, according to the report in the August 7th issue of Cell, a Cell Press journal. http://www.physorg.com/news168788864.html Chemistry Thu, 06 Aug 2009 15:10:01 EST news168788864 Noninvasive imaging (MRI) may aid physicians in the early diagnosis, staging and treatment of diabetes, according to a study performed at Massachusetts General Hospital and Harvard Medical School in Boston, MA. This is the first study of its kind to apply noninvasive imaging techniques to diabetes research. http://www.physorg.com/news168688947.html Medicine & Health Wed, 05 Aug 2009 11:03:05 EST news168688947 Crack open the latest medical textbook to the chapter on type 2, or adult-onset, diabetes, and you'll be hard pressed to find the term "immunology" anywhere. This is because metabolic conditions and immunologic conditions are, with a few exceptions, distant cousins. http://www.physorg.com/news167835602.html Medicine & Health Sun, 26 Jul 2009 14:00:42 EST news167835602 In the new issue of the Developmental Cell journal, a team of scientists at Singapore's Agency for Science, Technology and Research (A*STAR) and the University of North Carolina School of Medicine at Chapel Hill, report research findings about the molecular mechanisms behind the aging process, which has up till now been poorly understood, that offer the possibility that a novel, pharmacological approach could be developed to combat age-related disorders. http://www.physorg.com/news167406901.html Medicine & Health Tue, 21 Jul 2009 14:55:56 EST news167406901 Scientists have identified a master regulator gene for early embryonic development of the pancreas and other organs, putting researchers closer to coaxing stem cells into pancreatic cells as a possible cure for type1 diabetes. http://www.physorg.com/news167311578.html Medicine & Health Mon, 20 Jul 2009 12:50:01 EST news167311578 (PhysOrg.com) -- For years researchers have been searching for a way to treat diabetics by reactivating their insulin-producing beta cells, to no avail. Now, they may be one step closer. A protein, whose role in pancreatic development has long been recognized, has been discovered to play an additional and previously unknown regulatory role in the development of cells in the immature endocrine system. These cells ultimately give rise to pancreatic islet cells, which include beta cells. http://www.physorg.com/news166374064.html Medicine & Health Thu, 09 Jul 2009 16:01:40 EST news166374064 A low dose of oral interferon alpha shows promise in preserving beta cell function for patients with newly diagnosed type 1 diabetes, or juvenile diabetes, according to researchers at The University of Texas Medical School at Houston. http://www.physorg.com/news165656173.html Medicine & Health Wed, 01 Jul 2009 09:10:01 EST news165656173 A major study of three to 19 year-olds has provided vital data on the weight problems faced by the growing number of children and young people with type 1 diabetes, which is more prevalent in younger age groups than type 2 diabetes. http://www.physorg.com/news164883744.html Medicine & Health Mon, 22 Jun 2009 10:02:46 EST news164883744 Researchers at the University of Pittsburgh School of Medicine are trailblazing the molecular pathway that regulates replication of pancreatic beta cells, the insulin-producing cells that are lacking in people who have type 1 or type 2 diabetes. http://www.physorg.com/news163736694.html Medicine & Health Tue, 09 Jun 2009 03:25:32 EST news163736694 A drug widely used to treat Type 2 diabetes may have unintended effects on the pancreas that could lead to a form of low-grade pancreatitis in some patients and a greater risk of pancreatic cancer in long-term users, UCLA researchers have found. http://www.physorg.com/news160326333.html Medicine & Health Thu, 30 Apr 2009 16:05:54 EST news160326333 The use of pancreatic islets (hormone-producing cells) is increasing in diabetes research and may play an important role in future treatments, according to an article in the April 15 issue of JAMA, a theme issue on diabetes. http://www.physorg.com/news158930593.html Medicine & Health Tue, 14 Apr 2009 12:23:54 EST news158930593 Scientists at Burnham Institute for Medical Research (Burnham) and the University of California San Diego (UC San Diego) School of Medicine have demonstrated in mice that transplanted pancreatic precursor cells are protected from the immune system when encapsulated in polytetrafluorethylene (PTFE). The study, which suggests a new approach to treating Type 1 diabetes, was published online on April 8 in the journal Transplantation. http://www.physorg.com/news158505159.html Medicine & Health Thu, 09 Apr 2009 14:13:48 EST news158505159 A team of researchers from the Peninsula Medical School in the South West of England, the University of Brighton and the Department of Pathology at Glasgow Royal Infirmary, has found that a common family of viruses (enteroviruses) may play an important role in triggering the development of diabetes, particularly in children. These viruses usually cause symptoms similar to the common cold, or vomiting and diarrhoea. However, the team has now provided clear evidence that they are also found frequently in the pancreas of people who develop diabetes. http://www.physorg.com/news155486297.html Medicine & Health Thu, 05 Mar 2009 14:38:54 EST news155486297 Researchers at the Genomics Institute of the Novartis Research Foundation (GNF) have identified a set of compounds that can trigger the proliferation of insulin-producing cells in the pancreas, using sophisticated high-throughput screening techniques. http://www.physorg.com/news154789336.html Medicine & Health Wed, 25 Feb 2009 13:02:53 EST news154789336 Taking clues from their stem cell research, investigators at the University of California San Diego (UC San Diego) and Burnham Institute for Medical Research (Burnham) have discovered that a signaling pathway involved in normal pancreatic development is also associated with type 2 diabetes. Their findings, published online January 9 in Experimental Diabetes Research, could provide a potential new target for therapy. http://www.physorg.com/news153686015.html Medicine & Health Thu, 12 Feb 2009 18:34:49 EST news153686015 Researchers at the University of Pittsburgh School of Medicine have successfully induced human insulin-producing cells, known as beta cells, to replicate robustly in a living animal, as well as in the lab. The discovery not only could improve models and methods for studying diabetes, but also opens up new possibilities for treating the condition. http://www.physorg.com/news151072935.html Medicine & Health Tue, 13 Jan 2009 12:42:15 EST news151072935 In a finding that could significantly influence the way type 1 diabetes is treated, researchers at Albert Einstein College of Medicine of Yeshiva University have developed a technique for transplanting insulin-producing pancreatic cells that causes only a minimal immune response in recipients. http://www.physorg.com/news149947779.html Medicine & Health Wed, 31 Dec 2008 12:09:39 EST news149947779 Finnish scientists have reported a breakthrough in the attempts to understand the development of type 1 diabetes. They discovered disturbances in lipid and amino acid metabolism in children who later progressed to type 1 diabetes, also known as juvenile diabetes. The alterations preceded the autoimmune response by months to years. The study may prompt new approaches for prediction and prevention of type 1 diabetes in pre-autoimmune phase of the disease. http://www.physorg.com/news148735459.html Medicine & Health Wed, 17 Dec 2008 11:24:19 EST news148735459 Researchers at the Joslin Diabetes Center have shown that insulin-producing pancreatic beta cells can form after birth or after injury from progenitor cells within the pancreas that were not beta cells, a finding that contradicts a widely-cited earlier study that had concluded this is not possible. http://www.physorg.com/news146766762.html Medicine & Health Mon, 24 Nov 2008 16:32:42 EST news146766762 Drugs widely used to treat type 2 diabetes may be more likely to keep working if they are used in moderation, researchers at Washington University School of Medicine in St. Louis have found in a study using an animal model. http://www.physorg.com/news144395443.html Medicine & Health Tue, 28 Oct 2008 06:50:43 EST news144395443 A protein made by the liver in response to inflammation and used to treat patients suffering from a genetic form of emphysema has been shown to restore blood glucose levels in a mouse model of Type 1 diabetes mellitus, according to a new study led by researchers at Beth Israel Deaconess Medical Center (BIDMC). http://www.physorg.com/news143198754.html Medicine & Health Tue, 14 Oct 2008 10:25:54 EST news143198754 Affecting eight percent of America's population, diabetes can lead to blindness, kidney failure, strokes and heart disease. Thanks to Tel Aviv University researchers, a new cure - - based on advances in cell therapy - - may be within reach. http://www.physorg.com/news139580294.html Medicine & Health Tue, 02 Sep 2008 13:18:14 EST news139580294 Researchers have used a drug to achieve normal levels of blood sugar in animals genetically engineered to have abnormally high insulin levels. If this approach succeeds in humans, it could become an innovative medicine for children with congenital hyperinsulinism, a rare but potentially devastating genetic disease in which insulin levels become dangerously high. http://www.physorg.com/news136736496.html Chemistry Thu, 31 Jul 2008 15:21:36 EST news136736496