http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. The beneficial effects of anti-angiogenesis drugs in the treatment of the deadly brain tumors called glioblastomas appear to result primarily from reduction of edema - the swelling of brain tissue - and not from any direct anti-tumor effect, according to a study from Massachusetts General Hospital (MGH) researchers. Their report, to be published in the Journal of Clinical Oncology and receiving early online release, describes how treatment with the experimental drug cediranib reduced edema and improved survival in three mouse models of glioblastoma. http://www.physorg.com/news157616326.html Medicine & Health Mon, 30 Mar 2009 07:19:27 EST news157616326 The circadian clocks that set the rhythmic motion of our bodies for wakeful days and sleepy nights can also set us up for vascular disease when broken, Medical College of Georgia researchers say. http://www.physorg.com/news157210291.html Medicine & Health Wed, 25 Mar 2009 14:31:57 EST news157210291 To get a better look at the abnormalities that cause age-related macular degeneration (AMD), the leading cause of vision loss in Americans and Europeans over 50, the research groups of James Fujimoto at the Massachusetts Institute of Technology (MIT) and collaborators Jay Duker of the Tufts University School of Medicine, and Joel Schuman of the University of Pittsburgh School of Medicine have created ultra-detailed 3-D images of the eyes of more than 2,000 people from different ethnic groups, 400 of whom have AMD. Selected electronic data, published in the special Interactive Science Publishing (ISP) issue of Optics Express, the Optical Society's (OSA) open-access journal, may pave the way for new diagnostic software useful for developing new treatments. http://www.physorg.com/news156704904.html Medicine & Health Thu, 19 Mar 2009 18:09:05 EST news156704904 A group of scientists in California is trying to develop a cheaper, less invasive way to spot the early stages of retinal damage from diabetic retinopathy, the leading cause of blindness in American adults, before it leads to blindness. As described in the special Interactive Science Publishing (ISP) issue of Optics Express, the Optical Society's (OSA) open-access journal, the scientists are using beams of light to measure blood flow in the back of the eye. http://www.physorg.com/news156007813.html Physics Wed, 11 Mar 2009 16:30:59 EST news156007813 (PhysOrg.com) -- Harvard researchers have established a link between the growth of blood vessels and the mechanical stresses caused by the environment within which the vessels grow, a new understanding that researchers hope can lead to novel disease treatments based on manipulating blood flow to living tissues. http://www.physorg.com/news155836467.html Medicine & Health Mon, 09 Mar 2009 16:54:58 EST news155836467 We usually think of fish as a "heart-healthy" food. Now fish are helping researchers better understand how heart disease develops in studies that could lead to new drugs to slow disease and prevent heart attacks. http://www.physorg.com/news155495877.html Medicine & Health Thu, 05 Mar 2009 17:18:28 EST news155495877 Too little activity by gene regulators called PPARs appears to be a major player in the irreversible lung damage that can occur in children with heart defects, researchers say. http://www.physorg.com/news155473873.html Medicine & Health Thu, 05 Mar 2009 11:11:33 EST news155473873 Stem cells can thrive in segments of well-vascularized tissue temporarily removed from laboratory animals, say researchers at the Stanford University School of Medicine. Once the cells have nestled into the tissue's nooks and crannies, the so-called "bioscaffold" can then be seamlessly reconnected to the animal's circulatory system. http://www.physorg.com/news155225793.html Medicine & Health Mon, 02 Mar 2009 14:17:48 EST news155225793 By now, most people have read stories about how to "grow your own organs" using stem cells is just a breakthrough away. Despite the hype, this breakthrough has been elusive. A new report published in the March 2009 issue of The FASEB Journal brings bioengineered organs a step closer, as scientists from Stanford and New York University Langone Medical Center describe how they were able to use a "scaffolding" material extracted from the groin area of mice on which stem cells from blood, fat, and bone marrow grew. This advance clears two major hurdles to bioengineered replacement organs, namely a matrix on which stem cells can form a 3-dimensional organ and transplant rejection. http://www.physorg.com/news154869287.html Biology Thu, 26 Feb 2009 11:15:10 EST news154869287 (PhysOrg.com) -- Researchers at the University of Pennsylvania School of Medicine have unlocked the mystery of a puzzling human disease and gained insight into cardiovascular development, all thanks to a big-hearted fish. http://www.physorg.com/news154788885.html Medicine & Health Wed, 25 Feb 2009 12:58:24 EST news154788885 Researchers at Uppsala University have developed a new tool that makes it possible to study the signals in the body that control the generation of blood vessels.  The researchers` findings, published in the new issue of Lab on a Chip, enable scientists to determine what signals in the body attract or repel blood vessels, knowledge that is extremely interesting in tumor research. http://www.physorg.com/news154274706.html Chemistry Thu, 19 Feb 2009 14:06:43 EST news154274706 A Johns Hopkins engineer is trying to coax human stem cells to turn into networks of new blood vessels that could someday be used to replace damaged tissue in people with heart disease, diabetes and other illnesses. http://www.physorg.com/news154201708.html Medicine & Health Wed, 18 Feb 2009 17:49:10 EST news154201708 A study by researchers at the University of Cincinnati (UC) shows that high-fat diets, even if consumed for a short amount of time, can inflame fat tissue surrounding blood vessels, possibly contributing to cardiovascular disease. http://www.physorg.com/news154190358.html Medicine & Health Wed, 18 Feb 2009 14:40:04 EST news154190358 Platelets, tiny and relatively uncharted tenants of the bloodstream known mostly for their role in blood clotting, turn out to also rally sustained immune system inflammatory responses that play a critical role in organ transplant rejection, according to a new report from Johns Hopkins scientists. http://www.physorg.com/news154118265.html Medicine & Health Tue, 17 Feb 2009 18:39:04 EST news154118265 Our blood vessels provide all growing tissues with oxygen and nutrients. The growth of blood vessels (a process termed angiogenesis) is indispensable for the proper functioning of organs and the repair of tissues when they have become damaged. http://www.physorg.com/news153670072.html Medicine & Health Thu, 12 Feb 2009 14:08:19 EST news153670072 (PhysOrg.com) -- Cotton candy has delighted children for a century. Now it may have found a new role: helping scientists grow replacement tissues for people. The flossy stuff may be just right for creating networks of blood vessels within laboratory-grown bone, skin, muscle or fat for breast reconstruction, researchers suggest. http://www.physorg.com/news153589816.html Chemistry Wed, 11 Feb 2009 15:50:55 EST news153589816 The development of cancerous tumours is highly dependent on the nutrients the tumours receive through the blood. The team of Dr. Janusz Rak, of the Research Institute of the McGill University Health Centre (MUHC) at the Montreal Children's Hospital, including Dr. Khalid Al-Nedawi and Brian Meehan, has just discovered a new mechanism that tumours use to stimulate the growth of the blood vessels that feed them. http://www.physorg.com/news153575307.html Medicine & Health Wed, 11 Feb 2009 11:49:11 EST news153575307 Transplanting cells that replenish blood vessels can also restore nerve function in an animal model of diabetic neuropathy, Emory researchers have found. The results are described online this week in the journal Circulation. http://www.physorg.com/news152977005.html Medicine & Health Wed, 04 Feb 2009 13:37:29 EST news152977005 A pair of studies, led by Medical College of Wisconsin scientists at Children's Research Institute in Milwaukee, may translate into rapid molecular tests to distinguish between hemangiomas and congenital blood or lymph vessel malformations in infants. Hemangiomas are common birthmarks consisting of benign tumors of blood vessels. The studies appear in the January 29, 2009 issue of the journal Blood. http://www.physorg.com/news152464973.html Medicine & Health Thu, 29 Jan 2009 15:23:19 EST news152464973 The older the kidney, the worse it works - though exactly how much worse isn't known. But with a mean wait time of over three years for a kidney transplant, even old kidneys are in demand. The challenge for doctors is to determine a kidney's prospects prior to the operation. http://www.physorg.com/news152201256.html Medicine & Health Mon, 26 Jan 2009 14:08:20 EST news152201256 In a finding that could save thousands of lives a year, University of Utah School of Medicine researchers have shown that a blood vessel disorder leading to unpredictable, sometimes fatal, hemorrhagic strokes, seizures, paralysis or other problems is treatable with the same statin drugs that millions of people take to control high cholesterol. http://www.physorg.com/news152197183.html Medicine & Health Mon, 26 Jan 2009 13:00:15 EST news152197183 Looking at the retina in the eyes of patients with cerebral malaria has provided scientists with a vital insight into why malaria infection in the brain is so deadly. In a study funded by the Wellcome Trust and Fight for Sight and published today in the Journal of Infectious Diseases, researchers in Malawi have shown for the first time in patients that the build-up of infected blood cells in the narrow blood vessels of the brain leads to a potentially lethal lack of oxygen to the brain. http://www.physorg.com/news151222194.html Medicine & Health Thu, 15 Jan 2009 06:09:54 EST news151222194 They may never pose a challenge to Olympic superstar Michael Phelps, but the "microswimmers" developed by researchers in Spain and the United Kingdom could break a long-standing barrier to improving delivery of medications for cancer and other diseases. They describe the development of tiny, magnetically controlled particles, called "microswimmers," that doctors could use to precisely deliver medicine to diseased tissue. Their report appears in the December 25, 2008 issue of The Journal of Physical Chemistry B. http://www.physorg.com/news151001927.html Chemistry Mon, 12 Jan 2009 16:58:47 EST news151001927 Mice exposed to low temperatures develop more blood vessels in their adipose tissue and metabolise body fat more quickly, according to a new study from Karolinska Institutet. Scientists now hope to learn how to control blood vessel development in humans in order to combat obesity and diabetes. http://www.physorg.com/news150543426.html Medicine & Health Wed, 07 Jan 2009 09:37:06 EST news150543426 Researchers have found that two proteins which work in tandem in the brain's blood vessels present a double whammy in Alzheimer's disease. Not only do the proteins lessen blood flow in the brain, but they also reduce the rate at which the brain is able to remove amyloid beta, the protein that builds up in toxic quantities in the brains of patients with the disease. http://www.physorg.com/news149090408.html Biology Sun, 21 Dec 2008 14:00:08 EST news149090408 Using stem cell lines not typically combined, researchers at Columbia University Medical Center have designed a new way to "grow" bone and other tissues. http://www.physorg.com/news148571674.html Medicine & Health Mon, 15 Dec 2008 13:54:34 EST news148571674 Older adults who exercise regularly show increased cerebral blood flow and a greater number of small blood vessels in the brain, according to findings presented today at the annual meeting of the Radiological Society of North America (RSNA). http://www.physorg.com/news147359540.html Medicine & Health Mon, 01 Dec 2008 13:12:20 EST news147359540 Scientists at St. Jude Children's Research Hospital have discovered that a certain differentiated cell type is so ready to change its identity that it requires the constant expression of a gene called Prox1 to dissuade it. http://www.physorg.com/news147357294.html Medicine & Health Mon, 01 Dec 2008 12:34:54 EST news147357294 A team of researchers at Duke University Medical Center and the Université catholique de Louvain (UCL) has found that lactic acid is an important energy source for tumor cells. In further experiments, they discovered a new way to destroy the most hard-to-kill, dangerous tumor cells by preventing them from delivering lactic acid. http://www.physorg.com/news146421554.html Medicine & Health Thu, 20 Nov 2008 16:39:14 EST news146421554 Keeping germs from cooperating can delay the evolution of drug resistance more effectively than killing germs one by one with traditional drugs such as antibiotics, according to new research from The University of Arizona in Tucson. http://www.physorg.com/news146399724.html Biology Thu, 20 Nov 2008 10:35:24 EST news146399724