http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Many biological processes are controlled by small molecules known as microRNAs, which work by suppressing the expression of specific sets of genes. Xiang-Hang Luo and colleagues, at Second Xiangya Hospital of Central South University, People's Republic of China, have now identified a previously unknown microRNA (miR-2861) as crucial to bone maintenance in mice and humans. Of clinical importance, expression of functional miR-2861 was absent in two related adolescents with primary osteoporosis. http://www.physorg.com/news177620522.html Medicine & Health Mon, 16 Nov 2009 19:30:03 EST news177620522 An international team of scientists, led by researchers at the University of Pennsylvania School of Medicine, is taking the first step in developing a treatment for a rare genetic disorder called fibrodysplasia ossificans progressiva (FOP), in which the body's skeletal muscles and soft connective tissue turns to bone, immobilizing patients over a lifetime with a second skeleton. http://www.physorg.com/news177258526.html Medicine & Health Thu, 12 Nov 2009 14:50:03 EST news177258526 (PhysOrg.com) -- Any one of the 8 million Americans who suffer bone fractures each year knows how hard it is to wait for the bones to knit, or heal. Bone healing is also important for integration of dental implants for people with missing or damaged teeth. http://www.physorg.com/news174731260.html Chemistry Wed, 14 Oct 2009 09:40:02 EST news174731260 New research from Columbia University Medical Center has illuminated a previously unknown leptin-serotonin pathway in the brain that simultaneously promotes appetite and bone mass accrual. The research, which explains how leptin - well-known appetite-suppressing hormone - acts in the brain, is published in the Sept. 4 issue of Cell. http://www.physorg.com/news171199542.html Medicine & Health Thu, 03 Sep 2009 12:40:04 EST news171199542 Investigators at Hospital for Special Surgery, collaborating with researchers from other institutions, have contributed to the discovery that a gene called interferon regulator factor-8 (IRF-8) is involved in the development of diseases such as periodontitis (gum disease), rheumatoid arthritis and osteoporosis. The study, which will be published online August 30, ahead of print, in the journal Nature Medicine, could lead to new treatments in the future. http://www.physorg.com/news170860703.html Medicine & Health Sun, 30 Aug 2009 14:19:00 EST news170860703 Researchers at the University of Alabama at Birmingham (UAB) have discovered a molecular coupling factor that helps bones grow and remodel themselves to stay strong, a finding that could lead to better bone-building therapies and new osteoporosis drugs, the researchers said. http://www.physorg.com/news166270408.html Medicine & Health Wed, 08 Jul 2009 11:13:59 EST news166270408 After weight loss surgery, people have nearly twice the expected risk of breaking a bone and an even higher risk of a foot or hand fracture, a new study has found. http://www.physorg.com/news163939075.html Medicine & Health Thu, 11 Jun 2009 11:38:32 EST news163939075 (PhysOrg.com) -- Osteoporosis and periodontitis are common diseases whose sufferers must cope with weakness, injury and reduced function as they lose bone more quickly than it is formed. While the mechanism of bone destruction in these diseases is understood, scientists have had less information about how bone formation is impaired. http://www.physorg.com/news161949438.html Medicine & Health Tue, 19 May 2009 10:58:28 EST news161949438 Researchers at the University of Pennsylvania School of Medicine and the University of Connecticut have pinpointed the source of immature cells that spur misplaced bone growth. Unexpectedly, the major repository of bone-forming cells originates in blood vessels deep within skeletal muscle and other connective tissues, not from muscle stem cells themselves. The work also shows that cells important in the inflammatory response to injury trigger skeleton-stimulating proteins to transform muscle tissue into bone. http://www.physorg.com/news155315646.html Medicine & Health Tue, 03 Mar 2009 15:14:38 EST news155315646 Researchers have unraveled crucial details of how aging causes broken bones to heal slowly, or not at all, according to study results published today in the Journal of Bone and Mineral Research. The research team also successfully conducted preclinical tests on a potential new class of treatments designed to "rescue" healing capability lost to aging. http://www.physorg.com/news151241371.html Medicine & Health Thu, 15 Jan 2009 11:29:31 EST news151241371 (PhysOrg.com) -- Bone growth is controlled in the gut through serotonin, the same naturally present chemical used by the brain to influence mood, appetite and sleep, according to a new discovery from researchers at Columbia University Medical Center. Until now, the skeleton was thought to control bone growth, and serotonin was primarily known as a neurotransmitter acting in the brain. This new insight could transform how osteoporosis is treated in the future by giving doctors a way to increase bone mass, not just slow its loss. Findings are reported in the Nov. 26, 2008 issue of Cell. http://www.physorg.com/news146922394.html Medicine & Health Wed, 26 Nov 2008 11:46:34 EST news146922394 Scientists have discovered a crucial step in hormone-triggered bone growth, a finding that could lead to new osteoporosis drugs and better bone-building therapies, according to a new study. http://www.physorg.com/news144732228.html Medicine & Health Sat, 01 Nov 2008 04:23:48 EST news144732228 When a person is losing a significant amount of weight, they expect to notice changes in their body. However, they may overlook changes happening in their bones. During weight loss through calorie-restricted diets, bones are being remodeled - breaking down old bone and forming new bone - at an accelerated rate. At the same time, bone density is decreasing, causing increased fragility. http://www.physorg.com/news136481781.html Medicine & Health Mon, 28 Jul 2008 16:36:21 EST news136481781 Researchers at the University of Southern California, School of Dentistry have uncovered the health benefits of aspirin in the fight against osteoporosis. Forty-four million Americans, 68 percent of whom are women, suffer from the debilitating effects of osteoporosis according to the National Institute of Health. One out of every two women and one in four men over 50 will have an osteoporosis-related fracture in their lifetime. http://www.physorg.com/news134819508.html Medicine & Health Wed, 09 Jul 2008 10:51:48 EST news134819508