http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. DC-SCRIPT, or dendritic cell-specific transcript, is a key regulator of nuclear receptor activity that may have prognostic value in breast cancer, according to a new study published online December 14 in the Journal of the National Cancer Institute. http://www.physorg.com/news180029567.html Medicine & Health Mon, 14 Dec 2009 17:50:07 EST news180029567 A new study finds that women treated for breast cancer are at higher risk of cancer recurrence if they have dense breasts. Published in the December 15, 2009 issue of Cancer, a peer-reviewed journal of the American Cancer Society, the study's results indicate that breast cancer patients with dense breasts may benefit from additional therapies following surgery, such as radiation. http://www.physorg.com/news176963764.html Medicine & Health Mon, 09 Nov 2009 05:40:01 EST news176963764 The right combination of estrogen and a selective estrogen receptor modulator (SERM), which blocks the effects of estrogen in breast tissue, could relieve menopause symptoms and cut breast cancer risk, Yale researchers report in an abstract presented at the American Society for Reproductive Medicine (ASRM) scientific meeting in Atlanta, Georgia, October 17-21. http://www.physorg.com/news175190615.html Medicine & Health Mon, 19 Oct 2009 17:40:05 EST news175190615 Scientists at the University of Toronto have developed a new "lab-on-a-chip" technique that analyses tiny samples of blood and breast tissue to identify women at risk of breast cancer much more quickly than ever before. http://www.physorg.com/news174144025.html Chemistry Wed, 07 Oct 2009 14:21:07 EST news174144025 Mayo Clinic researchers have found that certain structural features within breast tissue can indicate a woman's individual cancer risk. The findings appear online today in the Journal of Clinical Oncology. http://www.physorg.com/news173987833.html Medicine & Health Mon, 05 Oct 2009 19:20:01 EST news173987833 Elevated levels of GLI1 (glioma-associated oncogene homolog 1) protein in human breast cancer are associated with unfavorable prognosis and progressive stages of disease. Researchers writing in the open access journal BMC Cancer found increased expression of GLI1 in samples taken from more advanced and less survivable tumors. http://www.physorg.com/news170360080.html Medicine & Health Mon, 24 Aug 2009 19:40:01 EST news170360080 Nationally, about ten percent of women in the US are recalled for a second mammogram after an abnormality is detected on the first one -for most women this can be very stressful. However the use of digital breast tomosynthesis and full-field digital mammography combined may be associated with a substantial decrease in recall rate, according to a study performed at UPMC in Pittsburgh, PA. Some researchers believe that digital breast tomosynthesis depicts the breast tissue in a way which may allow radiologists to identify some tumors which could be missed with standard two-dimensional mammography. http://www.physorg.com/news168689138.html Medicine & Health Wed, 05 Aug 2009 13:40:01 EST news168689138 Walter and Eliza Hall Institute scientists have found that a population of breast cells called luminal progenitor cells are likely to be responsible for breast cancers that develop in women carrying mutations in the gene BRCA1. http://www.physorg.com/news168439681.html Medicine & Health Sun, 02 Aug 2009 13:48:25 EST news168439681 The tubes that power X-ray machines are shrinking, improving the clarity and detail of their Superman-like vision. A team of nanomaterial scientists, medical physicists, and cancer biologists at the University of North Carolina has developed new lower-cost X-ray tubes packed with sharp-tipped carbon nanotubes for cancer research and treatment. http://www.physorg.com/news168015956.html Nanotechnology Tue, 28 Jul 2009 16:07:24 EST news168015956 Researchers at the U.S. Department of Energy`s (DOE) Brookhaven National Laboratory have demonstrated a new, highly detailed x-ray imaging technique that could be developed into a method for early diagnosis of Alzheimer`s disease. The technique has previously been used to look at tumors in breast tissue and cartilage in human knee and ankle joints, but this study is the first to test its ability to visualize a class of miniscule plaques that are a hallmark feature of Alzheimer`s disease. Their results will appear in a July 2009 edition of the journal NeuroImage. http://www.physorg.com/news164294141.html Medicine & Health Mon, 15 Jun 2009 14:16:09 EST news164294141 Exposure to dioxins during pregnancy harms the cells in rapidly-changing breast tissue, which may explain why some women have trouble breastfeeding or don't produce enough milk, according to a University of Rochester Medical Center study. http://www.physorg.com/news163820856.html Medicine & Health Wed, 10 Jun 2009 02:47:59 EST news163820856 Reporting online in the American Journal of Pathology, researchers from the Kimmel Cancer Center at Jefferson have implicated the loss of a stromal protein called caveolin-1 as a major new prognostic factor in patients with breast cancer, predicting early disease recurrence, metastasis and breast cancer patient survival. http://www.physorg.com/news160833169.html Medicine & Health Wed, 06 May 2009 12:54:10 EST news160833169 A unique mother-daughter study that used magnetic resonance to measure breast density in younger women shows that percent of breast water could be linked to the risk of breast cancer in middle age and older. http://www.physorg.com/news160275336.html Medicine & Health Thu, 30 Apr 2009 01:55:57 EST news160275336 Many studies determine hormone levels in the blood as a marker of breast cancer risk. But it hasn't been known whether these blood tests reflect what is happening in the breast tissue, where certain hormones fuel cancer. Researchers at Georgetown University Medical Center's (GUMC) Lombardi Comprehensive Cancer Center found that measuring the levels of four hormones in blood known to be linked to breast cancer doesn't necessarily reflect the levels of these hormones in the breast tissue itself. http://www.physorg.com/news159647853.html Medicine & Health Wed, 22 Apr 2009 19:38:34 EST news159647853 One of the most effective ways to prevent breast cancer is through a full-term pregnancy at an early age. Studies out of Fox Chase Cancer Center have linked this protective effect to the presence of human chorionic gonadotropin (hCG), a hormone produced by the placenta to maintain the early stages of pregnancy. Their findings in an animal model of breast cancer showed that rats exposed to hCG over a 21 day period (the length of rat pregnancy), are far less likely to develop breast cancer when exposed to a known carcinogen. http://www.physorg.com/news159464827.html Medicine & Health Mon, 20 Apr 2009 16:47:21 EST news159464827 Researchers are trying to open a door for a killer that breast cancer cells shut out. http://www.physorg.com/news154097558.html Chemistry Tue, 17 Feb 2009 12:53:26 EST news154097558 Human calmodulin-like protein (CLP) is found in many cell types including breast, thyroid, prostate, kidney, and skin. The protein can regulate many cell activities and has a highly specific expression. Gaining an understanding about the expression of CLP in oral epithelial cells and its possible downregulation (or lack of production) in cancer may be a potentially valuable marker in early detection of oral cancer. A new study in the Journal of Prosthodontics found that CLP is expressed in normal human oral muscosal cells and that downregulation of this protein may be an indicator of malignancy or cancer. http://www.physorg.com/news150557236.html Medicine & Health Wed, 07 Jan 2009 13:27:16 EST news150557236 Having dense breasts - areas that show up light on a mammogram - is strongly associated with increased breast cancer risk, but "why" remains to be answered. Now, by examining dense and non-dense tissue taken from the breasts of healthy volunteers, researchers from Mayo Clinic have found several potential links. http://www.physorg.com/news148488226.html Medicine & Health Sun, 14 Dec 2008 14:43:46 EST news148488226 New research may explain why breast cancer tends to be more aggressive in women with denser breast tissue. Breast cancer cells grown in dense, rigid surroundings step up their invasive activities, Vanderbilt-Ingram Cancer Center investigators report in the Sept. 9 issue of Current Biology. http://www.physorg.com/news138621191.html Medicine & Health Fri, 22 Aug 2008 10:53:11 EST news138621191 Whether a painless, portable device that uses electrical current rather than X-ray to look for breast cancer could be an alternative to traditional mammograms is under study at the Medical College of Georgia. http://www.physorg.com/news135957000.html Medicine & Health Tue, 22 Jul 2008 14:50:00 EST news135957000