http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Working with mice, scientists at Johns Hopkins publishing in the December issue of Neoplasia have shown that a protein made by a gene called "Twist" may be the proverbial red flag that can accurately distinguish stem cells that drive aggressive, metastatic breast cancer from other breast cancer cells. http://www.physorg.com/news179170966.html Medicine & Health Fri, 04 Dec 2009 17:43:06 EST news179170966 Australian scientists said Thursday they were to trial a revolutionary treatment which would allow women to regrow their breasts after cancer surgery. http://www.physorg.com/news177225674.html Medicine & Health Thu, 12 Nov 2009 06:00:03 EST news177225674 (PhysOrg.com) -- University of Florida researchers have grown tumors in mice using cells from inflamed but noncancerous colon tissue taken from human patients, a finding that sheds new light on colon cancer and how it might be prevented. http://www.physorg.com/news174579080.html Medicine & Health Mon, 12 Oct 2009 15:13:09 EST news174579080 (PhysOrg.com) -- A daily dose of aspirin can prevent the occurrence of cancer in people with a genetic predisposition towards Lynch syndrome, a Newcastle University scientist has told Europe`s largest cancer congress. Lynch syndrome is a condition which accounts for around 5 per cent of all colon cancers. http://www.physorg.com/news173369935.html Medicine & Health Mon, 28 Sep 2009 15:40:02 EST news173369935 In a one-two punch, a familiar diabetes drug reduced tumors faster and prolonged remission in mice longer than chemotherapy alone by targeting cancer stem cells, Harvard Medical School researchers reported in the September 14 online first edition of Cancer Research. http://www.physorg.com/news172146603.html Medicine & Health Mon, 14 Sep 2009 11:30:46 EST news172146603 Researchers at Stanford University School of Medicine have discovered, for the first time, a common molecular pathway that is used by both normal stem cells and cancer stem cells when they reproduce themselves. http://www.physorg.com/news168791714.html Medicine & Health Thu, 06 Aug 2009 16:00:01 EST news168791714 Walter and Eliza Hall Institute scientists have found that a population of breast cells called luminal progenitor cells are likely to be responsible for breast cancers that develop in women carrying mutations in the gene BRCA1. http://www.physorg.com/news168439681.html Medicine & Health Sun, 02 Aug 2009 13:48:25 EST news168439681 Researchers at UCLA's Jonsson Comprehensive Cancer Center, on a quest to find lung cancer stem cells, have developed a unique model to allow further investigation into the cells that many believe may be at the root of all lung cancers. http://www.physorg.com/news164363232.html Medicine & Health Tue, 16 Jun 2009 10:00:01 EST news164363232 In the battle against cancer, allies can come from unexpected sources. Research at The Jackson Laboratory has yielded a new approach to treating leukemia, one that targets leukemia-proliferating cells with drugs that are already on the market. http://www.physorg.com/news163599847.html Medicine & Health Sun, 07 Jun 2009 13:25:17 EST news163599847 Breast cancer patients who received chemotherapy prior to surgery had heightened levels of cancer-initiating stem cells in their bone marrow, and the level of such cells correlated to a tumor's lymph node involvement, according to research from The University of Texas M. D. Anderson Cancer Center. http://www.physorg.com/news161609613.html Medicine & Health Fri, 15 May 2009 12:34:17 EST news161609613 Much to the dismay of patients and physicians, cancer stem cells - tiny powerhouses that generate and maintain tumor growth in many types of cancers - are relatively resistant to the ionizing radiation often used as therapy for these conditions. Part of the reason, say researchers at Stanford University School of Medicine, is the presence of a protective pathway meant to shield normal stem cells from DNA damage. When the researchers blocked this pathway, the cells became more susceptible to radiation. http://www.physorg.com/news152977118.html Medicine & Health Wed, 04 Feb 2009 13:39:16 EST news152977118 After identifying an apparent population of cancer stem cells for neuroblastoma, researchers successfully used a reprogrammed herpes virus to block tumor formation in mice by targeting and killing the cells. http://www.physorg.com/news151737767.html Medicine & Health Wed, 21 Jan 2009 05:23:22 EST news151737767 One of the current handicaps of cancer treatments is the difficulty of aiming these treatments at destroying malignant cells without killing healthy cells in the process. But a new study by McMaster University researchers has provided insight into how scientists might develop therapies and drugs that more carefully target cancer, while sparing normal healthy cells. http://www.physorg.com/news150383139.html Biology Mon, 05 Jan 2009 13:05:39 EST news150383139 Scientists at St. Jude Children's Research Hospital have answered a central question in cancer biology: whether normal stem cells can give rise to tumors. Stem cells are immature cells that can renew themselves and give rise to mature differentiated cells that compose the range of body tissues. In recent years, researchers have developed evidence that cancers may arise from mutant forms of stem cells. http://www.physorg.com/news148745372.html Medicine & Health Wed, 17 Dec 2008 14:09:32 EST news148745372 Breast cancer stem cells are known to be involved in therapy resistance and the recurrence of cancerous tumors. A new study appearing in Clinical and Translational Science shows the mechanisms governing stem cell expansion in breast cancer (called Notch activity), and finds that therapy targeting a protein called cyclin D1 may block the expansion of cancerous stem cells. http://www.physorg.com/news145122787.html Medicine & Health Wed, 05 Nov 2008 15:53:07 EST news145122787 Researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute who first isolated cancer stem cells in adult brain tumors in 2004 have now identified a molecular mechanism that is involved in the development of these cells from which malignant brain tumors may originate. This could offer a target for scientists seeking treatments that would kill malignant brain tumors at their source and prevent them from recurring. http://www.physorg.com/news144062076.html Medicine & Health Fri, 24 Oct 2008 10:14:36 EST news144062076 After years of working toward this goal, scientists at the OU Cancer Institute have found a way to isolate cancer stem cells in tumors so they can target the cells and kill them, keeping cancer from returning. http://www.physorg.com/news140359659.html Medicine & Health Thu, 11 Sep 2008 13:47:39 EST news140359659 Stem cell scientists have developed a more accurate way of identifying aggressive forms of bowel cancer, which should eventually lead to better treatment and survival rates. Bowel cancer is the third most common cancer in the UK. http://www.physorg.com/news138435104.html Medicine & Health Wed, 20 Aug 2008 07:11:44 EST news138435104 Researchers at Georgetown University Medical Center have discovered that vitamin A, when applied to breast cancer cells, turns on genes that can push stem cells embedded in a tumor to morph into endothelial cells. These cells can then build blood vessels to link up to the body's blood supply, promoting further tumor growth. http://www.physorg.com/news135402781.html Medicine & Health Wed, 16 Jul 2008 04:53:01 EST news135402781 A gene that is overexpressed in 20 percent of breast cancers increases the number of cancer stem cells, the cells that fuel a tumor's growth and spread, according to a new study from the University of Michigan Comprehensive Cancer Center. http://www.physorg.com/news134819378.html Medicine & Health Wed, 09 Jul 2008 10:49:38 EST news134819378