http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Circulating metastatic breast cancer cells can lose their epithelial receptors, a process that enables them to travel through the bloodstream undetected, according to research from The University of Texas M. D. Anderson Cancer Center. http://www.physorg.com/news179824466.html Medicine & Health Sat, 12 Dec 2009 07:15:02 EST news179824466 Anti-estrogens as therapy for breast cancer may also reduce the risk of death from lung cancer, according to study results presented at the CTRC-AACR San Antonio Breast Cancer Symposium, held here Dec. 9-13, 2009. http://www.physorg.com/news179755832.html Medicine & Health Fri, 11 Dec 2009 12:20:02 EST news179755832 Genetic variations in the Sonic Hedgehog pathway increase the likelihood of recurrence, reduce survival time and limit response to therapy for people with non-muscle invasive bladder cancer, scientists from The University of Texas M. D. Anderson Cancer Center reported today at the American Association for Cancer Research Frontiers in Cancer Prevention Research Conference. http://www.physorg.com/news179581636.html Medicine & Health Wed, 09 Dec 2009 12:10:02 EST news179581636 Children and adolescents who survive cancer have a significantly higher risk of developing heart disease as young adults, according to the largest study on this issue published on bmj.com today. http://www.physorg.com/news179559355.html Medicine & Health Wed, 09 Dec 2009 05:36:18 EST news179559355 Cholesterol-lowering drugs known as statins are among the most prescribed medicines in the U.S. Now a new study by researchers at Fred Hutchinson Cancer Research Center indicates that statins may protect stem cell transplant patients from one of the most serious complications of the life-saving cancer therapy: graft-versus-host disease, or GVHD. The findings are reported in the Nov. 4 first edition of the journal Blood. http://www.physorg.com/news179165432.html Medicine & Health Fri, 04 Dec 2009 16:11:40 EST news179165432 (PhysOrg.com) -- Researchers at McGill University have discovered a previously unknown series of interactions between genes that control whether cells become cancerous. The discovery may lead to a new generation of targeted therapies tuned to individual patients, the researchers said. Their results are published today in the journal Cancer Cell. http://www.physorg.com/news176487250.html Medicine & Health Tue, 03 Nov 2009 16:30:01 EST news176487250 (PhysOrg.com) -- Trichostatin A, an agent initially investigated in the laboratory as a possible cancer therapy, has been shown to inhibit contractions in muscle from the uterus and could have a role in preventing premature labour. http://www.physorg.com/news175518850.html Medicine & Health Fri, 23 Oct 2009 12:30:03 EST news175518850 (PhysOrg.com) -- A powerful new biosensor developed by European researchers will help identify cells in the immune system that actively suppress tumour growth, then put them to use. Enlisting the patient?s own immune system would be like sending reinforcements for resistance fighters. http://www.physorg.com/news175517538.html Chemistry Fri, 23 Oct 2009 11:54:00 EST news175517538 Researchers at the University of Pittsburgh School of Medicine and the National Cancer Institute (NCI), part of the National Institutes of Health, may be hot on the heels of a Holy Grail of cancer therapy: They have found a way to not only protect healthy tissue from the toxic effects of radiation treatment, but also increase tumor death. The findings appear today in Science Translational Medicine. http://www.physorg.com/news175355067.html Medicine & Health Wed, 21 Oct 2009 15:00:03 EST news175355067 (AP) -- Texas gave birth to the modern oil industry, invented the handheld calculator and sent man to the moon. But can the Lone Star State cure cancer? http://www.physorg.com/news173724804.html Medicine & Health Fri, 02 Oct 2009 18:40:01 EST news173724804 In an advance toward better treatments for the most serious form of brain cancer, scientists in Illinois are reporting development of the first nanoparticles that seek out and destroy brain cancer cells without damaging nearby healthy cells. The study is scheduled for the Sept. 9 issue of ACS' Nano Letters. http://www.physorg.com/news171745889.html Nanotechnology Wed, 09 Sep 2009 20:12:29 EST news171745889 Scientists at Dana-Farber Cancer Institute have uncovered the mechanism behind a promising new approach to cancer treatment: damaging cancer cells' DNA with potent drugs while simultaneously preventing the cells from repairing themselves. http://www.physorg.com/news169725288.html Medicine & Health Mon, 17 Aug 2009 10:55:26 EST news169725288 A multi-institutional team of Boston-area researchers has discovered a chemical that works in mice to kill the rare but aggressive cells within breast cancers that have the ability to seed new tumors. http://www.physorg.com/news169385651.html Medicine & Health Thu, 13 Aug 2009 13:42:25 EST news169385651 In a study published online in advance of print in Stem Cells, Tufts researchers report that the STAT3 gene regulates cancer stem cells in brain cancer. Cancer stem cells have many characteristics of stem cells and are thought to be the cells that drive tumor formation. The researchers report that STAT3 could become a target for cancer therapy, specifically in Glioblastoma multiforme (GBM), a type of malignant and aggressive brain tumor. http://www.physorg.com/news169120154.html Medicine & Health Mon, 10 Aug 2009 10:49:38 EST news169120154 (PhysOrg.com) -- In 1957, shepherds in Idaho (USA) discovered that when pregnant sheep ate lilies of the species Veratrum californicum (corn lily, California false hellebore), their lambs were born with only one eye in the center of their foreheads, like a cyclops. The trigger for this was found to be the alkaloid cyclopamine. Cyclopamine has proven to be an effective candidate for cancer therapy in adult humans and is now undergoing clinical trials. http://www.physorg.com/news168850201.html Chemistry Fri, 07 Aug 2009 07:50:40 EST news168850201 Researchers at Stanford University School of Medicine have discovered, for the first time, a common molecular pathway that is used by both normal stem cells and cancer stem cells when they reproduce themselves. http://www.physorg.com/news168791714.html Medicine & Health Thu, 06 Aug 2009 16:00:01 EST news168791714 Melanoma is the most serious form of skin cancer, diagnosed in more than 50,000 new patients in the United States annually. While the rate of incidences continues to rise, survival rate has not improved and the race is on to find the genetic and cellular changes driving melanoma and to devise new means of detection and treatment. In a study published online in Genome Research, scientists have mapped chemical modifications of DNA in the melanoma genome, finding new markers that will help develop more effective treatment strategies to fight this disease. http://www.physorg.com/news165509319.html Medicine & Health Mon, 29 Jun 2009 15:49:20 EST news165509319 Chemists at the University of California, Santa Cruz, have developed novel compounds that show promise for photodynamic cancer therapy, which uses light-activated drugs to kill tumor cells. http://www.physorg.com/news164377656.html Chemistry Tue, 16 Jun 2009 14:00:01 EST news164377656 A new lung cancer therapy employing a vaporized viral vector to deliver a cancer-inhibiting molecule directly to lung tissue shows early promise in mouse trials, according to researchers at the Ministry of Education, Science and Technology in Korea. http://www.physorg.com/news163680472.html Medicine & Health Mon, 08 Jun 2009 11:48:35 EST news163680472 In a new study, Dana-Farber Cancer Institute scientists disprove a century-old theory about why cancer cells often have too many or too few chromosomes, and show that the actual reason may hold the key to a novel approach to cancer therapy. http://www.physorg.com/news163600003.html Medicine & Health Sun, 07 Jun 2009 13:27:37 EST news163600003 A vaccine for one of the most lethal cancers, advanced melanoma, has shown improved response rates and progression-free survival for patients when combined with the immunotherapy drug, Interleukin-2, according to researchers from The University of Texas M. D. Anderson Cancer Center. http://www.physorg.com/news163071438.html Medicine & Health Mon, 01 Jun 2009 10:39:48 EST news163071438 In technology that promises to one day allow drug delivery to be tailored to an individual patient and a particular cancer tumor, researchers at the University of California, San Diego School of Medicine, have developed an efficient system for delivering siRNA into primary cells. The work will be published in the May 17 in the advance on-line edition of Nature Biotechnology. http://www.physorg.com/news161750021.html Biology Sun, 17 May 2009 03:34:29 EST news161750021 (PhysOrg.com) -- As part of an effort to make high-precision particle cancer therapy accessible to more patients, a physicist at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory has developed a simpler, less-expensive gantry design for delivering tumor-killing particle beams. Brookhaven Science Associates, the company that manages the Lab for DOE, has applied for a U.S. non-provisional patent on the design, which is now available for licensing and commercial development. http://www.physorg.com/news161343117.html Medicine & Health Tue, 12 May 2009 10:33:17 EST news161343117 Breast cancer patients, individuals at risk for osteoporosis and those undergoing certain types of bone cancer therapies often take drugs containing bisphosphonates. These drugs have been found to place people at risk for developing osteonecrosis of the jaws (a rotting of the jaw bones). http://www.physorg.com/news160940557.html Medicine & Health Thu, 07 May 2009 18:43:09 EST news160940557 Researchers at Amgen are testing a fully human monoclonal antibody that inhibits the activity of insulin-like growth factors (IGF-1 and IGF-2) and appears to reduce pancreatic cancer cells in early testing, according to a report in Molecular Cancer Therapeutics, a journal of the American Association for Cancer Research. http://www.physorg.com/news158936367.html Medicine & Health Tue, 14 Apr 2009 14:00:10 EST news158936367 Johns Hopkins engineers have invented a method that could be used to help figure out how cancer cells break free from neighboring tissue, an "escape" that can spread the disease to other parts of the body. The new lab-on-a-chip, described in the March issue of the journal Nature Methods, could lead to better cancer therapies. http://www.physorg.com/news156602858.html Medicine & Health Wed, 18 Mar 2009 13:48:57 EST news156602858 Scientists studying chronic myeloid leukemia, more commonly known as CML, are one step closer to decoding the `genetic signature` of stem cells in this disease. They`ve identified a marker in a tiny but powerful subset of leukemia cells that could enable scientists to halt cancer cell growth in CML, and perhaps in other forms of cancer. http://www.physorg.com/news155929069.html Medicine & Health Tue, 10 Mar 2009 18:38:35 EST news155929069 Cancer and cell biology experts at the University of Cincinnati (UC) have identified a new tumor suppressor that may help scientists develop more targeted drug therapies to combat lung cancer. http://www.physorg.com/news150389078.html Medicine & Health Mon, 05 Jan 2009 14:44:38 EST news150389078