http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Biomedical researchers at the University of Central Florida have found a protein that could hold the key to treating one of the most common and aggressive brain tumors in adults. http://www.physorg.com/news180713480.html Medicine & Health Tue, 22 Dec 2009 14:40:01 EST news180713480 (PhysOrg.com) -- Researchers at McGill University have identified a protein that plays a key role in cell proliferation and is likely to promote cancer development. The work may lead to the development of new diagnostic tools adjusted for personalized treatments, the researchers said. Their results are published in the journal Proceedings of the National Academy of Sciences (PNAS). http://www.physorg.com/news180033486.html Chemistry Mon, 14 Dec 2009 17:20:27 EST news180033486 (PhysOrg.com) -- A team of Princeton University scientists has produced a systematic listing of the ways a particular cancerous cell has "gone wrong," giving researchers a powerful tool that eventually could make possible new, more targeted therapies for patients. http://www.physorg.com/news179683447.html Medicine & Health Thu, 10 Dec 2009 16:04:58 EST news179683447 Surgeons who successfully performed kidney transplants after removing small cancerous and benign masses from the donated organs, have published their results in the December issue of the urology journal BJUI. http://www.physorg.com/news179403431.html Medicine & Health Mon, 07 Dec 2009 11:00:04 EST news179403431 (PhysOrg.com) -- A virus that in nature infects only rabbits could become a cancer-fighting tool for humans. Myxoma virus kills cancerous blood-precursor cells in human bone marrow while sparing normal blood stem cells, a multidisciplinary team at the University of Florida College of Medicine has found. The findings are now online and will appear in an upcoming issue of the journal Leukemia. http://www.physorg.com/news179085253.html Medicine & Health Thu, 03 Dec 2009 18:30:03 EST news179085253 A recently discovered form of the protein that triggers blood clotting may play a key role in the molecular mechanisms leading to the growth of certain metastatic cancers, according to new research reported by an international team of scientists. http://www.physorg.com/news175791619.html Medicine & Health Mon, 26 Oct 2009 16:01:41 EST news175791619 Drugs made using unusual metals could form an effective treatment against colon and ovarian cancer, including cancerous cells that have developed immunity to other drugs, according to research at the University of Warwick and the University of Leeds. http://www.physorg.com/news175157795.html Chemistry Mon, 19 Oct 2009 07:57:05 EST news175157795 (PhysOrg.com) -- Researchers at Adaptimmune Limited and the University of Pennsylvania School of Medicine, today announced the approval of an Investigational New Drug (IND) application from the US Food and Drug Administration (FDA) and opening for enrollment of the first ever study using patients` cells carrying an engineered T cell receptor to treat HIV (SL9 HA-GAG-TCR). The trial may have important implications in the development of new treatments for HIV potentially slowing - or even preventing - the onset of AIDS. http://www.physorg.com/news174149785.html Medicine & Health Wed, 07 Oct 2009 15:57:11 EST news174149785 (PhysOrg.com) -- Think back to high-school biology and you may recall some basics about cellular respiration: how organelles called mitochondria function like little power stations, converting nutrients from food into a high-powered cell fuel called adenosine triphosphate, or ATP. http://www.physorg.com/news173636148.html Medicine & Health Thu, 01 Oct 2009 18:00:01 EST news173636148 Scientists label cells with coloured or glowing chemicals to observe how basic cellular activities differ between healthy and cancerous cells. Existing techniques for labelling cells are either too slow or too toxic to perform on live cells. Now, a study reviewed by Philip Dawson, a member of Faculty of 1000 Biology and leading authority in chemistry and cell biology, describes a novel labelling technique that uses a chemical reaction to make live cancer cells light up quickly and safely. http://www.physorg.com/news173008489.html Medicine & Health Thu, 24 Sep 2009 11:20:01 EST news173008489 Scientists at Fox Chase Cancer Center have discovered a unique method of attack that may be used to inhibit signaling enzymes called kinases, which often have a role in sustaining drug-resistant cancerous cells. They have confirmed that IPA-3, a small molecular inhibitor of a kinase called PAK1, targets the enzyme's regulatory domain, mimicking how enzymes are naturally regulated within cells. http://www.physorg.com/news171609385.html Medicine & Health Tue, 08 Sep 2009 06:40:01 EST news171609385 It may be one of nature's repulsive little blood-sucking parasites, but the humble tick could yield a future cure for cancers of the skin, liver and pancreas, Brazilian researchers have discovered. http://www.physorg.com/news170661506.html Medicine & Health Fri, 28 Aug 2009 07:08:36 EST news170661506 (PhysOrg.com) -- Scientists have discovered a way of allowing healthy cells to take charge of cancerous cells and stop them developing into tumours in what could provide a new approach to treating early-stage cancers. http://www.physorg.com/news170419763.html Medicine & Health Tue, 25 Aug 2009 12:00:01 EST news170419763 The tail ends of cellular protein templates, regions often thought relatively inconsequential, may actually play a role in preventing normal cells from becoming cancerous. http://www.physorg.com/news169993402.html Medicine & Health Thu, 20 Aug 2009 13:24:01 EST news169993402 A study published in the August 2009 edition of the Journal of Thoracic Oncology found that non-small cell lung cancer (NSCLC) patients could be more accurately staged at diagnosis by taking into account the level of visceral pleura invasion (VPI). VPI is the extension of a tumor beyond the elastic layer of the visceral pleura. http://www.physorg.com/news169895577.html Medicine & Health Wed, 19 Aug 2009 10:13:23 EST news169895577 Two University of Arizona researchers have formed a research team to design, build and evaluate two versions of an ovarian cancer medical imaging and screening instrument that will use holographic components in a new type of optical microscope. http://www.physorg.com/news169148323.html Medicine & Health Tue, 11 Aug 2009 02:40:01 EST news169148323 UT Southwestern Medical Center researchers are studying a new antigen to see whether it can track down and kill cancer cells in patients with recurring melanoma, the leading cause of skin cancer deaths. http://www.physorg.com/news169124584.html Medicine & Health Mon, 10 Aug 2009 12:03:28 EST news169124584 When cells experiencing DNA damage fail to repair themselves, they send a signal to their neighbors letting them know they're in trouble. The discovery, which shows that a process dubbed the DDR (DNA Damage Response) also controls communication from cell to cell, has implications for both cancer and aging. The findings appear in the July 13 online edition of the Nature Cell Biology. http://www.physorg.com/news166710999.html Biology Mon, 13 Jul 2009 13:42:11 EST news166710999 A specific biomarker, a protein released by dying tumor cells, has been identified as an effective tool in an animal model to gauge the response to a novel gene therapy treatment for glioblastoma mulitforme. The finding, reported in the July 1 issue of Clinical Cancer Research, paves the way for a Phase 1 clinical trial expected to begin in late 2009. http://www.physorg.com/news165645776.html Medicine & Health Wed, 01 Jul 2009 06:10:01 EST news165645776 A research team at Northwestern University has developed a tool that can precisely deliver tiny doses of drug-carrying nanomaterials to individual cells. The tool, called the nanofountain probe, functions in two different ways. In one mode, the probe acts like a fountain pen with drug-coated nanodiamonds serving as the ink, allowing researchers to create devices by `writing` with it. The second mode functions as a single-cell syringe, permitting direct injection of biomolecules or chemicals into individual cells. The research was led by Horacio Dante Espinosa, Ph.D., and Dean Ho, Ph.D., and the results appear in the journal Small. http://www.physorg.com/news165512374.html Nanotechnology Mon, 29 Jun 2009 21:10:03 EST news165512374 (PhysOrg.com) -- Using a "chemical nose" array of nanoparticles and polymers, researchers at the University of Massachusetts Amherst have developed a fundamentally new, more effective way to differentiate not only between healthy and cancerous cells but also between metastatic and non-metastatic cancer cells. It`s a tool that could revolutionize cancer detection and treatment, according to chemist Vincent Rotello and cancer specialist Joseph Jerry. http://www.physorg.com/news164998242.html Chemistry Tue, 23 Jun 2009 17:51:30 EST news164998242 Research by a Hebrew University of Jerusalem professor has led to the development of a product that has been shown in clinical trials to be successful in halting the growth of various types of cancer cells. http://www.physorg.com/news164258063.html Medicine & Health Mon, 15 Jun 2009 05:30:02 EST news164258063 New therapies developed following groundbreaking clinical trials appear to effectively target breast cancer and non-Hodgkin's lymphoma, according to research unveiled Sunday at a major cancer conference. http://www.physorg.com/news163058645.html Medicine & Health Mon, 01 Jun 2009 07:04:57 EST news163058645 A research team at Northwestern University has demonstrated a tool that can precisely deliver tiny doses of drug-carrying nanomaterials to individual cells. http://www.physorg.com/news161862130.html Nanotechnology Mon, 18 May 2009 10:42:37 EST news161862130 (PhysOrg.com) -- Scientists know that cancerous cells and normal cells have different physical features, but the details of these differences, and why they occur, are not well understood. In a recent edition of Nature Nanotechnology, researchers report measurements of certain physical differences between the surfaces of normal and cancerous cells, suggesting a new way to characterize cancer cells and a possible route for detection. http://www.physorg.com/news160716698.html Nanotechnology Tue, 05 May 2009 04:32:02 EST news160716698 Some DNA repair enzymes can become double-edged swords - If they work too slowly, they can block necessary cell maintenance and contribute to cell death. This could explain the somewhat mysterious success of the widely used cancer drug 5-Fluorouracil (5FU) and help clinicians to predict patient's response to chemotherapy, according to new findings from the University of Basel, Switzerland. http://www.physorg.com/news160129626.html Biology Tue, 28 Apr 2009 09:27:34 EST news160129626 By combining nanoparticles with a scorpion venom compound already being investigated for treating brain cancer, University of Washington researchers found they could cut the spread of cancerous cells by 98 percent, compared to 45 percent for the scorpion venom alone. http://www.physorg.com/news159108900.html Nanotechnology Thu, 16 Apr 2009 13:56:10 EST news159108900 Yuan et al. have identified another anti-cancer effect of the "longevity" protein SIRT1. By speeding the destruction of the tumor promoter c-Myc, SIRT1 curbs cell division. The study will be published online April 13 and will appear in the April 20 print issue of the Journal of Cell Biology. http://www.physorg.com/news158835232.html Biology Mon, 13 Apr 2009 09:54:19 EST news158835232 Excess amounts of a naturally fluorescent molecule found in all living cells could serve as a natural biomarker for cancer, according to bioengineers. http://www.physorg.com/news157889633.html Chemistry Thu, 02 Apr 2009 11:14:24 EST news157889633 The viscosity, or 'gloopiness', of different parts of cancer cells increases dramatically when they are blasted with light-activated cancer drugs, according to new images that provide fundamental insights into how cancer cells die, published in Nature Chemistry today. http://www.physorg.com/news156348853.html Chemistry Sun, 15 Mar 2009 15:15:01 EST news156348853