http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. (PhysOrg.com) -- Many cancerous tumors possess a genetic mutation that disables a tumor suppressor called PTEN. Now researchers at Washington University School of Medicine in St. Louis have shown why inactivation of PTEN allows tumors to resist radiation therapy. http://www.physorg.com/news163845046.html Medicine & Health Wed, 10 Jun 2009 09:31:10 EST news163845046 Researchers at the University of Pittsburgh School of Medicine are trailblazing the molecular pathway that regulates replication of pancreatic beta cells, the insulin-producing cells that are lacking in people who have type 1 or type 2 diabetes. http://www.physorg.com/news163736694.html Medicine & Health Tue, 09 Jun 2009 03:25:32 EST news163736694 (PhysOrg.com) -- A single cell - whether a yeast cell or one of your cells - is exquisitely sensitive to its surroundings. It receives input signals, processes the information, makes decisions, and issues commands for making the proper response. As with any control system, noise - errors, slip-ups, mis-reads - can get in the way of correct decision making. Virginia Tech biologists and engineers have created a mathematical model to explore the roles of noise in controlling the basic events of the cell cycle - DNA replication and cell division. http://www.physorg.com/news154708190.html Biology Tue, 24 Feb 2009 14:30:23 EST news154708190 (PhysOrg.com) -- Like high-profile politicians, pathogenic bacteria dispatch advance teams to make way for their arrival. But these bacterial agents don`t just secure a safe passage, as a Secret Service detail might do. Rather they are teams of molecules that bacteria inject into cells they want to colonize, sent to hijack their hosts` biochemistry to serve their master`s microbial needs. These molecules - called virulence factors - co-opt essential cell functions including the reproduction cycle and cell structure assembly, suppressing the cells` defenses against bacterial invasion and causing disease. http://www.physorg.com/news147625100.html Biology Thu, 04 Dec 2008 14:58:20 EST news147625100 A Scripps Research team has unraveled a new biochemical pathway that triggers a critical repair response to correct errors in the DNA replication process that could otherwise lead to harmful or fatal mutations in cells. Though the work focused on yeast cells, the team expects to find an analogous system in human cells that could be exploited as a target for potential therapies for cancers, which are often caused by such repair mechanisms going off course. The research was published today in an advanced, online issue of the Proceedings of the National Academy of Sciences. http://www.physorg.com/news137261363.html Biology Wed, 06 Aug 2008 17:09:23 EST news137261363