http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Dec. 8, 2009 - The Translational Genomics Research Institute (TGen) and Scottsdale Healthcare are testing a new drug specifically for thymic cancer based on early promising results at Scottsdale Healthcare. http://www.physorg.com/news179511023.html Medicine & Health Tue, 08 Dec 2009 16:30:02 EST news179511023 Intensive exercise prevented shortening of telomeres, a protective effect against aging of the cardiovascular system, according to research reported in Circulation: Journal of the American Heart Association. http://www.physorg.com/news178820544.html Medicine & Health Mon, 30 Nov 2009 16:40:01 EST news178820544 A man is a man and a mouse is a mouse, but if you talk to a few biomedical scientists about their research, at least one is likely to spring the term `mouse model` on you. http://www.physorg.com/news174843609.html Biology Thu, 15 Oct 2009 16:42:25 EST news174843609 Research is being carried out to design and synthesise a new generation of compounds that act on the tubulin molecule, involved in cell multiplication, through a mechanism that has not yet been used in chemotherapy. The researchers will then evaluate its anticarcinogenic potential for later application as a therapeutic treatment. This work is being done by the Organic Synthesis group of the Department of Inorganic and Organic Chemistry at the Universitat Jaume I (UJI) in Castellón, Spain. http://www.physorg.com/news171640001.html Medicine & Health Wed, 09 Sep 2009 02:50:01 EST news171640001 The tail ends of cellular protein templates, regions often thought relatively inconsequential, may actually play a role in preventing normal cells from becoming cancerous. http://www.physorg.com/news169993402.html Medicine & Health Thu, 20 Aug 2009 13:24:01 EST news169993402 "A biologist, a physicist, and a nanotechnologist walk into a..." sounds like the start of a joke. Instead, it was the start of a collaboration that has helped to decipher a critical, but so far largely unstudied, phase of how cells divide. Errors in cell division can cause mutations that lead to cancer, and this study could shed light on the role of chromosome abnormalities in uncontrolled cell replication. http://www.physorg.com/news169736758.html Biology Mon, 17 Aug 2009 14:20:02 EST news169736758 (PhysOrg.com) -- Using new genetic tools, Cornell researchers have found that some stem cells in mice behave dramatically different than in fruit flies, where most of the pioneering stem cell work has been conducted. The findings could have important implications for understanding how some cancers might be initiated, say the researchers. http://www.physorg.com/news169480057.html Biology Fri, 14 Aug 2009 15:40:07 EST news169480057 Scientists from the Department of Biological Sciences and the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed a quantitative, mathematical model of DNA replication and cell division for the bacterium Caulobacter crescentus. C. crescentus, an alpha-proteobacterium that inhabits freshwater, seawater and soils, is an ideal organism for genetic and computational biology studies due to the wealth of molecular information that has been accumulated by researchers. It also plays a key role in global carbon cycling in its natural environment. http://www.physorg.com/news169448410.html Biology Fri, 14 Aug 2009 06:00:42 EST news169448410 Research at the Walter and Eliza Hall Institute into the mechanics of how two types of white blood cells grow and die is fundamentally changing the development of computer models that are used to predict how immune system cells respond to a pathogenic threat. http://www.physorg.com/news167390887.html Medicine & Health Tue, 21 Jul 2009 10:50:01 EST news167390887 (PhysOrg.com) -- K-fibers, structures long thought to play a key role in the alignment of chromosomes prior to cell division, are not required after all, say Indiana University and New York State Department of Health scientists. http://www.physorg.com/news166113443.html Biology Mon, 06 Jul 2009 16:10:01 EST news166113443 Computer scientists at Harvard have developed a framework for studying the arrangement of tissue networks created by cell division across a diverse set of organisms, including fruit flies, tadpoles, and plants. http://www.physorg.com/news164453458.html Biology Wed, 17 Jun 2009 10:31:28 EST news164453458 From the valves in a human heart to the quills on a porcupine to the petals on a summer lily, the living world is as varied as it is vast. For this to be possible, the cells that make up these living things must be just as varied. Parent cells must be able to divide in ways that create daughter cells that are different from each other, a process called asymmetric division. Scientists know how this happens in animals, but the process in plants has been a mystery. http://www.physorg.com/news163942287.html Biology Thu, 11 Jun 2009 12:31:53 EST news163942287 No human is a clone of their parents but the same cannot be said for other living things. While your DNA is a combination of half your mother and half your father, other species do things differently. The advantage of clonal reproduction is that it produces an individual exactly like an existing one -which would be very useful for farmers who could replicate the best of their animals or crops without the lottery of sexual reproduction. Clonal reproduction of crop species took a step closer to being realised with new research published in PLoS Biology this week. http://www.physorg.com/news163736388.html Biology Tue, 09 Jun 2009 03:21:05 EST news163736388 Researchers from the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine have uncovered a remarkable property of the contractile ring, a structure required for cell division. Understanding how the contractile ring works to divide the cell may facilitate development of therapies to prevent uncontrolled cell division in cancer. http://www.physorg.com/news162734567.html Medicine & Health Thu, 28 May 2009 13:04:04 EST news162734567 Specialized motor proteins that transport cargo within cells could be turned into nanoscale machines for drug delivery, according to bioengineers. Chemical alteration of the proteins' function could also help inhibit the growth of cancerous tumors. http://www.physorg.com/news156775386.html Biology Fri, 20 Mar 2009 13:43:45 EST news156775386 Manuela Baccarini of the Centre for Molecular Biology of the University of Vienna, Austria, investigates a group of proteins which are important for cell division and therefore also for uncontrolled cell growth as occurring during cancerogenesis. Some experiments now lead her together with her team to an unexpected trace: she discovered an unknown regulation mechanism of the MEK enzymes, the key elements of the MAP signal transduction pathway. The results of this FWF project are now published in the journal Nature Structural & Molecular Biology. http://www.physorg.com/news154080525.html Biology Tue, 17 Feb 2009 08:09:27 EST news154080525 The last step of the cell cycle is the brief but spectacularly dynamic and complicated mitosis phase, which leads to the duplication of one mother cell into two daughter cells. In mitosis, the chromosomes condense and the nucleus breaks down. http://www.physorg.com/news153322908.html Biology Sun, 08 Feb 2009 13:43:11 EST news153322908 Before a cell can divide into two, first it must duplicate its genetic material--the DNA packed in its chromosomes. The two new sets of chromosomes then have to be separated from one another and correctly distributed to the resulting "daughter" cells, so that both daughter cells are genetically identical to the original, or "parent," cell. http://www.physorg.com/news153075893.html Medicine & Health Thu, 05 Feb 2009 17:05:31 EST news153075893 (PhysOrg.com) -- Dartmouth Medical School researchers have found two proteins that work in concert to ensure proper chromosome segregation during cell division. Their study is in the January 2009 issue of the journal Nature Cell Biology. http://www.physorg.com/news151343442.html Medicine & Health Fri, 16 Jan 2009 15:50:42 EST news151343442 Researchers from the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine have identified a key step required for cell division in a study that could help improve therapies to treat cancer. Their work describing the mechanism of the contractile ring - a structure that pinches the mother cell into two daughter cells - has been published in the December 5 issue of the journal Science. http://www.physorg.com/news148049853.html Biology Tue, 09 Dec 2008 12:57:33 EST news148049853 (PhysOrg.com) -- A previously unknown mutation discovered in a common roundworm holds the promise of new treatments for obesity in humans, McGill University researchers say. Their study was published Dec. 3 in the journal Nature, and was funded by the Canadian Cancer Society and the Canadian Institutes of Health Research. http://www.physorg.com/news147959984.html Biology Mon, 08 Dec 2008 11:59:44 EST news147959984 Biologists have discovered a mechanism that is critical to cytokinesis -- nature's completion of mitosis, where a cell divides into two identical daughter cells. http://www.physorg.com/news147622713.html Biology Thu, 04 Dec 2008 14:18:33 EST news147622713 A Swedish research group has discovered a new mechanism for cell division in a microorganism found in extremely hot and acidic conditions. The results of the research offer insights into evolution, but also into the functioning of the human body. The research has been recently published in PNAS, the magazine of the American National Academy of Sciences. Thijs Ettema, member of the research group, received a Rubicon grant from NWO in 2006 to gain experience abroad. http://www.physorg.com/news146833462.html Biology Tue, 25 Nov 2008 11:04:22 EST news146833462 (PhysOrg.com) -- MIT researchers have shown how a cell motor protein exerts the force to move, enabling functions such as cell division. http://www.physorg.com/news146766659.html Biology Mon, 24 Nov 2008 16:30:59 EST news146766659 A Florida State University College of Medicine research team led by Yanchang Wang has discovered an important new layer of regulation in the cell division cycle, which could lead to a greater understanding of the way cancer begins. http://www.physorg.com/news146511629.html Medicine & Health Fri, 21 Nov 2008 17:40:29 EST news146511629 A study of how one protein enzyme, BubR1, helps make sure chromosomes are equally distributed during mitosis might explain how the process of cell division goes so awry in cancer, according to researchers from Fox Chase Cancer Center. Their findings might offer a better understanding of the processes behind cancer-cell survival and drug-resistance. http://www.physorg.com/news146133713.html Medicine & Health Mon, 17 Nov 2008 08:41:53 EST news146133713 It is well known that plants growing under unfavourable conditions are generally smaller than those growing in stress-free conditions: indeed it is estimated that in the US, abiotic stress reduces the yield of agricultural crops by an average of 22%. A spectacular example of the effect of stress - in this case, repeated wounding - on plant growth is given by bonsai trees, in which every aspect of their stature, including height, girth, and size of leaves, is uniformly reduced to as little as 5% of that of their untreated sister trees. However, the mechanism of wound-induced stunting remains obscure. http://www.physorg.com/news145623433.html Biology Tue, 11 Nov 2008 10:57:13 EST news145623433 A novel cell division mechanism has been discovered in a microorganism that thrives in hot acid. The finding may also result in insights into key processes in human cells, and in a better understanding of the main evolutionary lineages of life on Earth. The study is published today in the online version the American National Academy of Sciences, PNAS. http://www.physorg.com/news144408546.html Biology Tue, 28 Oct 2008 10:29:06 EST news144408546 VIB researchers at Ghent University (Belgium) have discovered the substance that governs the formation of root offshoots in plants, and how it works. Root offshoots are vitally important for plants - and for farmers. Plants draw the necessary nutrients from the soil through their roots. Because they do this best with a well-branched root system, plants must form offshoots of their roots at the right moment. The VIB researchers describe how this process is controlled in the prominent professional journal Science. http://www.physorg.com/news143987252.html Biology Thu, 23 Oct 2008 13:27:32 EST news143987252 (PhysOrg.com) -- Like a sentry guarding the castle walls, a molecular messenger inside adult stem cells sounds the alarm when it senses hazards that could allow the invasion of an insidious enemy: Cancer. The alarm bell halts the process of cell division in its tracks, preventing an error that could lead to runaway cell division and eventually, tumor formation. http://www.physorg.com/news143295152.html Medicine & Health Wed, 15 Oct 2008 13:12:32 EST news143295152