http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. In order to maintain muscle strength with age, cells must rid themselves of the garbage that accumulates in them over time, just as it does in any household, according to a new study in the December issue of Cell Metabolism. In the case of cells, that waste material includes spent organelles, toxic clumps of proteins, and pathogens. http://www.physorg.com/news178892532.html Medicine & Health Tue, 01 Dec 2009 13:00:02 EST news178892532 Even the anticipation of sweets may cause our muscles to start taking up more blood sugar, say researchers reporting in the December issue of Cell Metabolism. That message is delivered via neurons in the brain's hypothalamus containing the chemical known as orexin and the sympathetic nervous system, the studies in mice and rats suggest. http://www.physorg.com/news178892306.html Medicine & Health Tue, 01 Dec 2009 12:19:29 EST news178892306 Many people who are overweight or obese develop insulin resistance and type 2 diabetes at some stage in their lives. A European research team has now discovered that obese people have large amounts of the molecule CXCL5, produced by certain cells in fatty tissue. http://www.physorg.com/news178279547.html Medicine & Health Tue, 24 Nov 2009 10:30:01 EST news178279547 How a specific gene within the pancreas affects secretion of insulin has been discovered by researchers from the Hebrew University of Jerusalem, in collaboration with Japanese and American universities. Their work opens the way for a new understanding of possible paths to battle diabetes and diabetes-related health problems, which are on the rise all over the world. http://www.physorg.com/news177244751.html Biology Thu, 12 Nov 2009 10:50:01 EST news177244751 If worms are any indication, all the sugar in your diet could spell much more than obesity and type 2 diabetes. Researchers reporting in the November issue of Cell Metabolism, a Cell Press publication, say it might also be taking years off your life. http://www.physorg.com/news176474656.html Medicine & Health Tue, 03 Nov 2009 13:30:01 EST news176474656 A cellular protein from a family involved in several human diseases is crucial for the proper production and release of insulin, new research has found, suggesting that the protein might play a role in diabetes. http://www.physorg.com/news175787060.html Biology Mon, 26 Oct 2009 14:47:01 EST news175787060 (PhysOrg.com) -- Results from comprehensive assessments of diabetes' effects on cell metabolism may aid efforts to reduce diabetic damage to nerves, blood vessels and other tissues, according to researchers at Washington University School of Medicine in St. Louis and elsewhere. http://www.physorg.com/news175418901.html Medicine & Health Thu, 22 Oct 2009 08:40:01 EST news175418901 (PhysOrg.com) -- It was once thought that the two communities of cells within a cancerous breast tumor - fast-growing malignant cells and the normal cells that surround them - existed independently, without interaction. Then evidence emerged indicating that the normal-looking cells encouraged cells within the tumor to become malignant, but how the one community influenced the other wasn't known. http://www.physorg.com/news175353047.html Medicine & Health Wed, 21 Oct 2009 15:00:05 EST news175353047 One of the biggest mysteries about diabetes is why specialized cells in the pancreas stop secreting insulin, which the body needs in order to store glucose from food. A team from the Children's Hospital of Eastern Ontario (CHEO) Research Institute has identified a protein that inhibits insulin production in mice - work that offers a new way of understanding, and perhaps of one day treating, both Type 1 and Type 2 diabetes. http://www.physorg.com/news174138674.html Chemistry Wed, 07 Oct 2009 12:52:34 EST news174138674 We've all heard about the damage that reactive oxygen species (ROS) - aka free radicals - can do to our bodies and the sales pitches for antioxidant vitamins, skin creams or "superfoods" that can stop them. In fact, there is considerable scientific evidence that chronic ROS production within cells can contribute to human diseases, including insulin resistance and type 2 diabetes. http://www.physorg.com/news174052401.html Medicine & Health Tue, 06 Oct 2009 13:40:24 EST news174052401 Researchers have fresh insight into an evolutionarily ancient way that cells cope when oxygen levels decline, according to a new study in the October 7th issue of Cell Metabolism. In studies of cells taken from the lining of human pulmonary arteries, they show that a microRNA - a tiny bit of RNA that regulates the activity of particular genes and thus the availability of certain proteins - allows cells to shift their metabolic gears, in a process known as the Pasteur effect. http://www.physorg.com/news174050396.html Medicine & Health Tue, 06 Oct 2009 12:40:01 EST news174050396 Type 2 diabetes, the most common form of diabetes, is increasing at an alarming state with more than 180 million people affected worldwide. With the rising incidence of obesity, a major risk factor for the onset of type 2 diabetes, this metabolic disorder represents a major health concern. A group from the Ecole Polytechnique Fédérale de Lausanne, Switzerland, now shows that there may exist new ways to fight these disorders. http://www.physorg.com/news171032050.html Medicine & Health Tue, 01 Sep 2009 14:10:01 EST news171032050 Researchers may have found a key ingredient in the recipe that leads from obesity to chronic low-grade inflammation, according to a report in the September issue of Cell Metabolism. http://www.physorg.com/news171028922.html Medicine & Health Tue, 01 Sep 2009 13:20:01 EST news171028922 A study in the September issue of Cell Metabolism, a Cell Press publication, may give new meaning to the adage, "You are what you eat." http://www.physorg.com/news171028127.html Biology Tue, 01 Sep 2009 13:00:01 EST news171028127 (PhysOrg.com) -- The normal ageing process has long been linked to problems with cell respiration, the process through which the cells extract energy from nutrients. Researchers at the Swedish medical university Karolinska Institutet have now shown how certain proteins that are synthesised in the cellular mitochondria - popularly known as the cells' power plants - become unstable and disintegrate, which in turn can impair cell respiration and cause premature ageing. http://www.physorg.com/news168770330.html Medicine & Health Thu, 06 Aug 2009 09:39:22 EST news168770330 A gut hormone first described in 1928 plays an unanticipated and important role in the remote control of blood sugar production in the liver, according to a report in the August 6th Cell Metabolism, a Cell Press publication. What's more, the researchers show that rats fed a high-fat diet for a few days become resistant to the glucose-lowering hormone known as cholecystokinin (CCK). http://www.physorg.com/news168697036.html Medicine & Health Wed, 05 Aug 2009 13:30:01 EST news168697036 As we all know from experience, people eat not only because they are hungry, but also because the food just simply tastes too good to pass up. Now, a new study in the August 6th Cell Metabolism, a Cell Press publication, helps to explain how leptin, a hormone produced by fat tissue, influences that motivation to eat. http://www.physorg.com/news168696652.html Medicine & Health Wed, 05 Aug 2009 13:11:17 EST news168696652 A Monash University study has proven a critical link between obesity and the onset of Type 2 diabetes, a discovery which could lead to the design of a drug to prevent the disease. http://www.physorg.com/news166270497.html Medicine & Health Wed, 08 Jul 2009 11:15:45 EST news166270497 Scientists at the European Molecular Biology Laboratory (EMBL) and the University of Heidelberg, Germany, have come a step closer to understanding how cholesterol levels are regulated. In a study published today in the journal Cell Metabolism, the researchers identified 20 genes that are involved in this process. Besides giving scientists a better idea of where to look to uncover the mechanisms that ensure cholesterol balance is maintained, the discovery could lead to new treatments for cholesterol-related diseases. http://www.physorg.com/news166191890.html Medicine & Health Tue, 07 Jul 2009 13:25:21 EST news166191890 Obesity very often leads to insulin resistance, and now researchers reporting in the July 8 issue of Cell Metabolism, a Cell Press publication, have uncovered another factor behind that ill consequence. The newly discovered culprit -a protein known as pigment epithelium-derived factor (PEDF for short) -is secreted by fat cells. They also report evidence to suggest that specifically blocking that protein's action may reverse some of the health complications that come with obesity. http://www.physorg.com/news166191801.html Biology Tue, 07 Jul 2009 13:24:09 EST news166191801 (PhysOrg.com) -- Researchers at the University of Glasgow believe they have found a potential new treatment for cardiovascular disease which reduces blood pressure. http://www.physorg.com/news165510349.html Medicine & Health Mon, 29 Jun 2009 18:40:03 EST news165510349 (PhysOrg.com) -- Cornell scientists have discovered how two related proteins and their roles in a key molecular pathway are critical to creating obesity-causing fat cells. http://www.physorg.com/news163266213.html Medicine & Health Wed, 03 Jun 2009 16:44:35 EST news163266213 By lending them a gene normally reserved for other classes of animals, researchers have shown they can rescue flies from their Parkinson's-like symptoms, including movement defects and excess free radicals produced in power-generating cellular components called mitochondria. The gene swap also protects healthy flies' mitochondria, and to a large extent the flies themselves, from the damaging effects of cyanide and other toxins, the team reports in the May issue of Cell Metabolism, a Cell Press publication. http://www.physorg.com/news160752389.html Biology Tue, 05 May 2009 14:27:31 EST news160752389 A common misconception about arterial plaque is that it inevitably leads to a heart attack or a stroke. New research at Columbia University Medical Center, however, sheds light on why so few plaques in any given individual actually cause a problem. Furthermore, the research has identified a key protein that may promote the conversion from benign to dangerous plaques. http://www.physorg.com/news160751426.html Biology Tue, 05 May 2009 14:11:45 EST news160751426 Many diseases derive from problems with cellular respiration, the process through which cells extract energy from nutrients. Researchers at the Swedish medical university Karolinska Institutet have now discovered a new function for a protein in the mitochondrion - popularly called the cell's power station - that plays a key part in cell respiration. http://www.physorg.com/news158405697.html Biology Wed, 08 Apr 2009 10:35:13 EST news158405697 It's basically a given that diets loaded with fat can lead to considerable health problems. But a new study in the April issue of Cell Metabolism, a Cell Press publication, shows that in some cases diets that are high in both fat and protein can be even worse. http://www.physorg.com/news158328667.html Biology Tue, 07 Apr 2009 13:11:35 EST news158328667 An inflammatory factor already linked to several diseases, including pulmonary disease, lung cancer, and arthritis, may also be responsible for the insulin resistance that comes with obesity, according to a new study published in the April issue of Cell Metabolism, a Cell Press publication. http://www.physorg.com/news158327353.html Medicine & Health Tue, 07 Apr 2009 12:50:24 EST news158327353 Two University of Rhode Island scientists have revealed how a cancer causing protein is regulated by reactive oxygen species (ROS) -- a type of stress signal. Their findings provide new insight into how this protein normally behaves in human cells and may help in the design of drugs targeting specific cancers. http://www.physorg.com/news157287306.html Medicine & Health Thu, 26 Mar 2009 11:55:43 EST news157287306 A report in the March issue of Cell Metabolism, a Cell Press publication, has found that a signal known to play a role during fasting also switches on early in the fat tissue of obese mice as they progress toward type 2 diabetes. Moreover, treatments that block that "fasting signal" in fat prevent the animals' resistance to insulin, according to the researchers. http://www.physorg.com/news155309238.html Biology Tue, 03 Mar 2009 13:28:17 EST news155309238 Researchers have found what appears to be a major culprit behind the loss of insulin-producing β cells from the pancreases of people with diabetes, a critical event in the progression of the disease. http://www.physorg.com/news152893015.html Biology Tue, 03 Feb 2009 14:17:58 EST news152893015