http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Research into the controversial drug thalidomide reveals that the mechanism through which the drug causes limb defects is the same process which causes it to damage internal organs and other tissues. The article, published in Bio-Essays, outlines the challenges surrounding thalidomide research and claims that confirmation of a 'common mechanism' could lead to new treatments for Leprosy, Crohn's Disease, AIDS and some forms of cancer. http://www.physorg.com/news177679646.html Medicine & Health Tue, 17 Nov 2009 11:50:01 EST news177679646 The probiotic, Bacillus polyfermenticus, can help mice recover from colitis, a new study has found. Mice treated with B. polyfermenticus during the non-inflammatory period of the disease had reduced rectal bleeding, their tissues were less inflamed and they gained more weight than mice that did not receive the treatment. http://www.physorg.com/news175748244.html Medicine & Health Mon, 26 Oct 2009 04:20:02 EST news175748244 New findings related to an uncommon genetic disorder may impact the diagnosis and treatment of inflammatory bowel disease (IBD), the most common chronic gastrointestinal illness in children and teens. Two million Americans have IBD which involves inflammation of the gastrointestinal tract. http://www.physorg.com/news174239504.html Medicine & Health Thu, 08 Oct 2009 16:52:10 EST news174239504 A research team from Hungary investigated the probability of disease behavior changes in a well-characterized Crohn's disease cohort with strict clinical follow-up. They found that perianal disease, small bowel disease, smoking, prior steroid use, early AZA or AZA/biological therapy are all predictors of disease behavior change in CD patients. http://www.physorg.com/news169120957.html Medicine & Health Mon, 10 Aug 2009 15:10:02 EST news169120957 Infectious-disease specialists at UT Southwestern Medical Center have demonstrated that a cannibalistic process in cells plays a key role in limiting Salmonella infection. http://www.physorg.com/news168538515.html Medicine & Health Mon, 03 Aug 2009 17:15:55 EST news168538515 Researchers from Case Western Reserve University School of Medicine identified a novel link between ITCH, a gene known to regulate inflammation in the body and NOD2, a gene which causes the majority of genetic Crohn's Disease diagnoses. ITCH, when malfunctioning, causes widespread inflammatory diseases, including inflammatory bowel disease, gastritis, uncontrolled skin inflammation, and pulmonary pneumonitis. http://www.physorg.com/news166360829.html Medicine & Health Thu, 09 Jul 2009 12:30:02 EST news166360829 Scientists at The University of Nottingham are investigating whether stem cell markers could have a role to play in speeding up wound healing in patients suffering from inflammatory bowel disease (IBD). http://www.physorg.com/news160154197.html Medicine & Health Tue, 28 Apr 2009 16:16:58 EST news160154197 (PhysOrg.com) -- Researchers have discovered that a long-defunct gene was resurrected during the course of human evolution. This is believed to be the first evidence of a doomed gene - infection-fighting human IRGM - making a comeback in the human/great ape lineage. http://www.physorg.com/news155563245.html Medicine & Health Fri, 06 Mar 2009 12:01:22 EST news155563245 Discovering the different genes that contribute to a complex disease is like searching in the proverbial haystack for an unknown number of needles--some much smaller than others, often blending into the background, and many of them widely separated from each other. But if some needles are linked to each other by fine threads, you might pull out clumps of them together. http://www.physorg.com/news154876287.html Medicine & Health Thu, 26 Feb 2009 13:12:06 EST news154876287 We may be a long way off from using genetics to reliably gauge our risks for specific diseases, say researchers at the University of Pittsburgh Graduate School of Public Health in a study published on Feb. 5 in the online journal PLoS Genetics. Yet, many companies currently offer personalized genetic testing for diseases like cancer, heart disease and diabetes, and tout the ability of DNA testing to predict future health risks. http://www.physorg.com/news153145607.html Medicine & Health Fri, 06 Feb 2009 12:27:26 EST news153145607 The administration of infliximab after intestinal resective surgery was found to be effective at preventing endoscopic and histological recurrence of Crohn's disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute. To date, there have been no randomized controlled trials evaluating infliximab for postoperative Crohn's disease prevention. http://www.physorg.com/news152727226.html Medicine & Health Sun, 01 Feb 2009 16:19:04 EST news152727226 Children with newly diagnosed cases of inflammatory bowel disease have higher concentrations of folate in their blood than individuals without IBD, according to a new study led by researchers at the University of California, San Francisco and UC Berkeley. The findings bring into question the previously held theory that patients with IBD are prone to folate - also known as folic acid - deficiency. http://www.physorg.com/news152011513.html Medicine & Health Sat, 24 Jan 2009 09:30:22 EST news152011513 Researchers have uncovered why some dietary fats, specifically long-chain fats, such as oleic acid (found in olive oil), are more prone to induce inflammation. Long-chain fats, it turns out, promote increased intestinal absorption of pro-inflammatory bacterial molecules called lipopolysaccharides (LPS). This study appears in the January issue of JLR. http://www.physorg.com/news150652159.html Medicine & Health Thu, 08 Jan 2009 15:49:19 EST news150652159 Researchers at McGill University, the Research Institute of the McGill University Health Centre (RI MUHC) and the McGill University and Génome Québec Innovation Centre, along with colleagues at other Canadian and Belgian institutions, have discovered DNA variations in a gene that increases susceptibility to developing Crohn's disease. Their study was published in the January issue of the journal Nature Genetics. http://www.physorg.com/news150646381.html Medicine & Health Thu, 08 Jan 2009 14:13:01 EST news150646381