http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Side effects associated with several commonly-prescribed dementia drugs may be putting elderly Canadians at risk, says Queen's University Geriatrics professor Sudeep Gill. http://www.physorg.com/news162662525.html Medicine & Health Wed, 27 May 2009 17:02:59 EST news162662525 There are several risk factors for the development of Alzheimer's disease and vascular dementia. Based on an increasing number of studies linking these risk factors with Vitamin D deficiency, an article in the current issue of the Journal of Alzheimer's Disease (May 2009) by William B. Grant, PhD of the Sunlight, Nutrition, and Health Research Center (SUNARC) suggests that further investigation of possible direct or indirect linkages between Vitamin D and these dementias is needed. http://www.physorg.com/news162562458.html Medicine & Health Tue, 26 May 2009 13:14:53 EST news162562458 (AP) -- Marketing executives at British drugmaker AstraZeneca PLC for years blocked efforts by company scientists to raise concerns antipsychotic drug Seroquel caused weight gain and other problems, saying that would harm sales, plaintiff lawyers say. http://www.physorg.com/news162041479.html Medicine & Health Wed, 20 May 2009 12:31:43 EST news162041479 If grandma seems to forget things, will she end up demented? These days, memory loss is one of the very few symptoms that may signal which 70-year-olds risk developing dementia. This is shown in a doctoral thesis at the Sahlgrenska Academy at the University of Gothenburg, Sweden. http://www.physorg.com/news162040794.html Medicine & Health Wed, 20 May 2009 12:20:32 EST news162040794 A new study shows that older people who are thinner or are losing weight quickly are at a higher risk of developing dementia, especially if they started out overweight or obese. The research is published in the May 19, 2009, print issue of Neurology, the medical journal of the American Academy of Neurology. http://www.physorg.com/news161883192.html Medicine & Health Mon, 18 May 2009 16:35:36 EST news161883192 (AP) -- Working a few years beyond retirement could help stave off Alzheimer's disease, according to a new British study published Monday. http://www.physorg.com/news161860463.html Medicine & Health Mon, 18 May 2009 10:14:50 EST news161860463 A new tool can help predict whether people age 65 and older have a high risk of developing Alzheimer's disease. Research on the tool is published in the May 13, 2009, online issue of Neurology, the medical journal of the American Academy of Neurology. http://www.physorg.com/news161454345.html Medicine & Health Wed, 13 May 2009 17:26:11 EST news161454345 A potential vaccine for Alzheimer's disease also has been shown in mice to slow the weakening of muscles associated with inclusion body myositis, a disorder that affects the elderly. http://www.physorg.com/news161439371.html Medicine & Health Wed, 13 May 2009 13:16:42 EST news161439371 Early diagnosis and treatment of Alzheimer's disease could save millions or even billions of dollars while simultaneously improving care, according to new work by University of Wisconsin-Madison researchers. http://www.physorg.com/news161358238.html Medicine & Health Tue, 12 May 2009 14:44:31 EST news161358238 (PhysOrg.com) -- Change the lighting; improve your health. It's a strategy researchers from Case Western Reserve University's Frances Payne Bolton School of Nursing and the School of Medicine, the Geriatric Research Education and Clinical Center at the Louis Stokes Cleveland Veterans Affairs Medical Center (GRECC), Rensselaer Polytechnic Institute's Lighting Research Center and GE Consumer & Industrial have begun to test in a long-term care facility where daylight, which has proven health benefits, is not readily available. http://www.physorg.com/news161350081.html Medicine & Health Tue, 12 May 2009 12:28:36 EST news161350081 Levels of biomarkers in the cerebrospinal fluid of individuals with very mild dementia may be associated with the rate at which their thinking, learning and memory skills decline, according to a report in the May issue of Archives of Neurology. http://www.physorg.com/news161278742.html Medicine & Health Mon, 11 May 2009 16:39:25 EST news161278742 A new study shows that nonsteroidal anti-inflammatory drugs (NSAIDs), such as the pain relievers ibuprofen and naproxen, do not prevent Alzheimer's disease or other forms of dementia. Instead, the risk of developing dementia in the study's very elderly population (most were over age 83 when they developed dementia) was 66 percent higher among heavy NSAID users than among people who used little or no NSAIDs, according to research published online today in Neurology(R), the medical journal of the American Academy of Neurology. http://www.physorg.com/news159640015.html Medicine & Health Wed, 22 Apr 2009 17:27:27 EST news159640015 Researchers at the Yerkes National Primate Research Center, Emory University, developed a test in nonhuman primates that is now using infrared eye tracking to detect mild cognitive impairment (MCI) in humans. The researchers hope the advanced technology will be helpful in predicting the onset of Alzheimer's disease. The test, which is featured in the current online issue of The American Journal of Alzheimer's Disease and Other Dementias, is helping researchers further understand the role of the brain structures critical to human memory. http://www.physorg.com/news159025771.html Medicine & Health Wed, 15 Apr 2009 14:51:24 EST news159025771 Having hypoglycemic (low blood sugar level) episodes that are severe enough to require hospitalization are associated with a greater risk of dementia for older adults with type 2 diabetes, according to a study in the April 15 issue of JAMA, a theme issue on diabetes. http://www.physorg.com/news158926730.html Medicine & Health Tue, 14 Apr 2009 11:19:50 EST news158926730 New therapeutic approaches in Alzheimer's disease are urgently needed. Work led by Professor Mark Pepys FRS over more than 20 years has identified a protein known as serum amyloid P component (SAP) as a possible therapeutic target in Alzheimer's disease. In collaboration with Roche he developed a new small molecule drug, CPHPC, which specifically targets SAP and removes it from the blood. In the exciting new work reported now in the PNAS, the Pepys team together with Professor Martin Rossor and colleagues from the Dementia Research Centre of UCL's Institute of Neurology, have shown that the drug also removes SAP from the brains of patients with Alzheimer's disease. http://www.physorg.com/news158864374.html Medicine & Health Mon, 13 Apr 2009 18:00:08 EST news158864374 A recent study by Mount Sinai faculty suggests that a gene associated with onset of type-2 diabetes also decreases in Alzheimer's disease dementia cases. The research, led by Dr. Giulio Maria Pasinetti, MD, Ph.D., The Aidekman Family Professor in Neurology, and Professor of Psychiatry and Geriatrics and Adult Development at Mount Sinai School of Medicine, was published this week in the scientific journal, Archives of Neurology. http://www.physorg.com/news158584038.html Medicine & Health Fri, 10 Apr 2009 12:08:36 EST news158584038 Investigators at Burnham Institute for Medical Research (Burnham) have demonstrated that attacks on the mitochondrial protein Drp1 by the free radical nitric oxide -which causes a chemical reaction called S-nitrosylation -mediates neurodegeneration associated with Alzheimer's disease. Prior to this study, the mechanism by which beta-amyloid protein caused synaptic damage to neurons in Alzheimer's disease was unknown. These findings suggest that preventing S-nitrosylation of Drp1 may reduce or even prevent neurodegeneration in Alzheimer's patients. The paper was published in the April 3 issue of the journal Science. http://www.physorg.com/news157900580.html Medicine & Health Thu, 02 Apr 2009 14:16:44 EST news157900580 In a study conducted by the Laboratory of Neuropsychology of the Université de Caen Basse-Normandie and published by Elsevier in the April 2009 issue of Cortex, researchers studied for the first time autobiographical memory in a group of semantic dementia (SD) patients according to disease progression. They highlighted that at early stages of the disease those patients could recall recent memories, but also lasting memories from their youth which tend to disappear as dementia evolves. Mechanisms at the root of this autobiographical memory impairment result from storage deficits combined with faulty retrieval strategies. http://www.physorg.com/news157900501.html Medicine & Health Thu, 02 Apr 2009 14:15:33 EST news157900501 Last fall, scientists from the University of Minnesota returned from Kentucky with some 600 preserved brains and 439 boxes filled with memories. That's how the world-famous Nun Study of Alzheimer's disease came home to Minnesota, where it first began. http://www.physorg.com/news157228208.html Medicine & Health Wed, 25 Mar 2009 19:34:08 EST news157228208 (PhysOrg.com) -- A precise, new nanotechnology treatment for drug addiction may be on the horizon as the result of research conducted at the University at Buffalo. http://www.physorg.com/news157053913.html Nanotechnology Mon, 23 Mar 2009 19:08:59 EST news157053913 People with memory problems are less at risk of developing dementia than previously thought, a new study led by the University of Leicester and Nottinghamshire Healthcare NHS Trust reveals. http://www.physorg.com/news157038529.html Medicine & Health Mon, 23 Mar 2009 14:49:24 EST news157038529 (PhysOrg.com) -- Scientists have discovered what could be causing Alzheimer`s disease sufferers to go on to develop epilepsy. http://www.physorg.com/news156698574.html Medicine & Health Thu, 19 Mar 2009 16:23:38 EST news156698574 (AP) -- You've heard that diabetes hurts your heart, your eyes, your kidneys. New research indicates a more ominous link: That diabetes increases the risk of getting Alzheimer's disease and may speed dementia once it strikes. http://www.physorg.com/news156442403.html Medicine & Health Mon, 16 Mar 2009 17:14:23 EST news156442403 People who have lost brain cells in the hippocampus area of the brain are more likely to develop dementia, according to a study published in the March 17, 2009, print issue of Neurology, the medical journal of the American Academy of Neurology. http://www.physorg.com/news156440974.html Medicine & Health Mon, 16 Mar 2009 16:51:07 EST news156440974 A test capable of confirming or ruling out Alzheimer's disease has been validated and standardized by researchers at the University of Pennsylvania School of Medicine. By measuring cerebrospinal fluid (CSF) concentrations of two of the disease's biochemical hallmarks - amyloid beta42 peptide and tau protein - the test also predicted whether a person's mild cognitive impairment would convert to Alzheimer's disease over time. Researchers were able to detect this devastating disease at the earliest stages, before dementia symptoms appeared and widespread irreversible damage occurred. The findings hold promise in the search for effective pharmaceutical therapies capable of halting the disease. http://www.physorg.com/news156435142.html Medicine & Health Mon, 16 Mar 2009 15:13:05 EST news156435142 Alzheimer's disease causes misfolding and aggregation of a protein fragment known as amyloid beta and its deposition as plaques in the brain. This process triggers a cascade of event that leads to neurodegeneration. A new study has found that the deadly transformation of amyloid beta into neurotoxic aggregates can be prevented through its interaction with a variant form of the amyloid beta itself. This opens up new prospects for therapies for the disease. http://www.physorg.com/news156088909.html Medicine & Health Thu, 12 Mar 2009 15:02:34 EST news156088909 VIB (the Flanders Institute for Biotechnology, Belgium) researchers connected to the Born-Bunge Institute and the University of Antwerp discovered the amount of growth factor progranulin in blood is a predictor of Frontotemporal Dementia (FTD). Progranulin plays a major role in the survival of brain cells. People producing less progranulin have higher risk of contracting FTD. The researchers developed a test, measuring the amount of progranulin in the blood thus predicting a person's risk. This offers possibilities for early detection. http://www.physorg.com/news155558617.html Medicine & Health Fri, 06 Mar 2009 10:44:08 EST news155558617 Within five years innovative 'smart' sensing systems that will help the UK's 700,000 dementia sufferers live independently at home could be available commercially. http://www.physorg.com/news155386837.html Medicine & Health Wed, 04 Mar 2009 11:01:03 EST news155386837 People who have parents diagnosed with Alzheimer's disease or dementia perform less well on formal memory testing when compared to people of the same age whose parents never developed Alzheimer's disease or other dementia. This is true even in middle-aged persons who do not have a diagnosis of clinical stroke or dementia, according to a Boston University School of Medicine (BUSM) study. This study has been selected to be presented at a Plenary Session at the American Academy of Neurology's 61st Annual Meeting in Seattle, Wash from April 25 - May 2. http://www.physorg.com/news154264525.html Medicine & Health Thu, 19 Feb 2009 11:15:56 EST news154264525 People who have parents diagnosed with Alzheimer's disease or dementia may be more likely to have memory loss themselves in middle age, according to a study released today that will be presented at the American Academy of Neurology's 61st Annual Meeting in Seattle, April 25 to May 2, 2009. http://www.physorg.com/news154202503.html Medicine & Health Wed, 18 Feb 2009 18:02:01 EST news154202503