http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Researchers at Mayo Clinic have discovered the first gender-linked susceptibility gene for late-onset Alzheimer's disease. http://www.physorg.com/news150905504.html Medicine & Health Sun, 11 Jan 2009 14:11:44 EST news150905504 A Mayo Clinic-led international consortium has found a mechanism that may help explain Parkinson's and other neurological disorders. http://www.physorg.com/news150904281.html Medicine & Health Sun, 11 Jan 2009 13:51:21 EST news150904281 Genetic variations that can predispose children to a serious disease that damages the heart have been identified in a genome-wide association study of Kawasaki Disease, published today in PLoS Genetics. http://www.physorg.com/news150695589.html Medicine & Health Fri, 09 Jan 2009 03:53:09 EST news150695589 A long-standing system for assessing the risk of cardiovascular disease amongst older people should be replaced with something more accurate, according to a study published today on bmj.com. http://www.physorg.com/news150695292.html Medicine & Health Fri, 09 Jan 2009 03:48:12 EST news150695292 Researchers have uncovered why some dietary fats, specifically long-chain fats, such as oleic acid (found in olive oil), are more prone to induce inflammation. Long-chain fats, it turns out, promote increased intestinal absorption of pro-inflammatory bacterial molecules called lipopolysaccharides (LPS). This study appears in the January issue of JLR. http://www.physorg.com/news150652159.html Medicine & Health Thu, 08 Jan 2009 15:49:19 EST news150652159 Bladder cancer is much more likely to be deadly for women and African-Americans, but the reasons long believed to explain the phenomenon account for only part of the differences for such patients compared to their white and male counterparts, according to results published in the Jan. 1 issue of the journal Cancer. http://www.physorg.com/news150646734.html Medicine & Health Thu, 08 Jan 2009 14:18:54 EST news150646734 Researchers at McGill University, the Research Institute of the McGill University Health Centre (RI MUHC) and the McGill University and Génome Québec Innovation Centre, along with colleagues at other Canadian and Belgian institutions, have discovered DNA variations in a gene that increases susceptibility to developing Crohn's disease. Their study was published in the January issue of the journal Nature Genetics. http://www.physorg.com/news150646381.html Medicine & Health Thu, 08 Jan 2009 14:13:01 EST news150646381 Two previously identified pathways associated with aging in mice are connected, say researchers at the Stanford University School of Medicine. The finding reinforces what researchers have recently begun to suspect: that the age-related degeneration of tissues, organs and, yes, even facial skin with which we all struggle is an active, deliberate process rather than a gradual failure of tired cells. Derailing or slowing this molecular betrayal, although still far in the future, may enable us to one day tack years onto our lives -- or at least delay the appearance of that next wrinkle. http://www.physorg.com/news150642332.html Biology Thu, 08 Jan 2009 13:05:32 EST news150642332 An international consortium of researchers, including major contribution from a team led by Dr. John D. Rioux, a professor of medicine at the Université de Montréal and the Montreal Heart Institute, has identified genetic markers associated with risk for ulcerative colitis. The findings, published in the advance online journal Nature Genetics, bring researchers closer to understanding the biological pathways involved in the disease and may lead to the development of new treatments that specifically target them. http://www.physorg.com/news150642174.html Medicine & Health Thu, 08 Jan 2009 13:02:54 EST news150642174 An innovative approach for implanting a new aortic heart valve without open-heart surgery is being offered to patients at NewYork-Presbyterian Hospital/Columbia University Medical Center. Known as the PARTNER (Placement of AoRTic traNscathetER valves) trial, this Phase 3 multicenter study is being led by national co-principal investigators Dr. Martin Leon and Dr. Craig Smith and is focused on the treatment of patients who are at high risk or not suitable for open-heart valve replacement surgery. http://www.physorg.com/news150561085.html Medicine & Health Wed, 07 Jan 2009 14:31:25 EST news150561085 A Boston University School of Medicine-led research team has discovered a more efficient way to create induced Pluripotent Stem (iPS) cells, derived from mouse fibroblasts, by using a single virus vector instead of multiple viruses in the reprogramming process. The result is a powerful laboratory tool and a significant step toward the application of embryonic stem cell-like cells for clinical purposes such as the regeneration of organs damaged by inherited or degenerative diseases, including emphysema, diabetes, inflammatory bowel disease, and Alzheimer's Disease. http://www.physorg.com/news150558593.html Biology Wed, 07 Jan 2009 13:49:53 EST news150558593 Patients with advanced Parkinson disease (PD) who received deep brain stimulation treatment had more improvement in movement skills and quality of life after six months than patients who received other medical therapy, but also had a higher risk of a serious adverse events, according to a study in the January 7 issue of JAMA. http://www.physorg.com/news150483770.html Medicine & Health Tue, 06 Jan 2009 17:02:50 EST news150483770 Implantable cardioverter defibrillators (ICDs) can improve survival in patients with heart damage - even those in their 70s - according to research reported in Circulation: Cardiovascular Quality and Outcomes. http://www.physorg.com/news150482825.html Medicine & Health Tue, 06 Jan 2009 16:47:05 EST news150482825 Researchers at North Carolina State University and the Centers for Disease Control and Prevention have produced the first link between a species of bacteria most commonly found in sheep and human illness. http://www.physorg.com/news150473724.html Medicine & Health Tue, 06 Jan 2009 14:15:24 EST news150473724 Research on the mechanisms involved in neurodegenerative diseases such as Alzheimer's, stroke, dementia, Parkinson's and multiple sclerosis, to name a few, has taken a step forward thanks to the work of biological sciences Ph.D. student Sonia Do Carmo, supervised by Professor Éric Rassart of the Université du Québec à Montreal (UQAM) Biological Sciences Department, in collaboration with researchers at the Armand-Frappier Institute and the University of Valladolid in Spain. http://www.physorg.com/news150468573.html Medicine & Health Tue, 06 Jan 2009 12:49:33 EST news150468573 Mutation of a gene that helps proteins migrate in and out of the cell's genetic command center - the nucleus - puts some families at higher risk for the degenerative brain disease acute necrotizing encephalopathy (ANE). http://www.physorg.com/news150468352.html Medicine & Health Tue, 06 Jan 2009 12:45:52 EST news150468352 Men with type 2 diabetes and men with previous heart attack or stroke had a 3 to 4 fold risk of cardiovascular death compared to men without either disease in the years following the first acute event, according to a study in CMAJ. http://www.physorg.com/news150398280.html Medicine & Health Mon, 05 Jan 2009 17:18:00 EST news150398280 (PhysOrg.com) -- Men across the Asia-Pacific region have consistently higher mortality and hospitalization rates for chronic obstructive pulmonary disease (COPD) than corresponding rates for women in the region. http://www.physorg.com/news150389593.html Medicine & Health Mon, 05 Jan 2009 14:53:13 EST news150389593 Scientists from the Gladstone Institute of Neurological Disease (GIND), UCSF, and Stanford have discovered that a certain type of collagen, collagen VI, protects brain cells against amyloid-beta (Aβ) proteins, which are widely thought to cause Alzheimer's disease (AD). While the functions of collagens in cartilage and muscle are well established, before this study it was unknown that collagen VI is made by neurons in the brain and that it can fulfill important neuroprotective functions. http://www.physorg.com/news150386598.html Medicine & Health Mon, 05 Jan 2009 14:03:18 EST news150386598 (PhysOrg.com) -- When there is a threat of disease during pregnancy, mothers produce less aggressive sons with more efficient immune systems, researchers at The University of Nottingham have discovered. http://www.physorg.com/news150373790.html Biology Mon, 05 Jan 2009 10:29:50 EST news150373790 An international team led by University of Pittsburgh School of Medicine researchers has identified genetic markers associated with risk for ulcerative colitis. The findings, which appear today as an advance online publication of the journal Nature Genetics, bring researchers closer to understanding the biological pathways involved in the disease and may lead to the development of new treatments that specifically target them. http://www.physorg.com/news150298032.html Medicine & Health Sun, 04 Jan 2009 13:27:12 EST news150298032 Researchers from Duke University Medical Center have identified a variation in a particular gene that increases susceptibility to early coronary artery disease. For years, scientists have known that the devastating, early-onset form of the disease was inherited, but they knew little about the gene(s) responsible until now. The results are published January 2 in the open-access journal PLoS Genetics. http://www.physorg.com/news150179720.html Medicine & Health Sat, 03 Jan 2009 04:35:20 EST news150179720 (PhysOrg.com) -- Children of mothers who took acid-suppressive drugs during pregnancy had a 1.5 times higher incidence of asthma when compared with children who were not exposed to the drugs in utero, finds a large population-based study by researchers at Children`s Hospital Boston. http://www.physorg.com/news150121295.html Medicine & Health Fri, 02 Jan 2009 12:21:35 EST news150121295 Neurologists have observed for decades that Lewy bodies, clumps of aggregated proteins inside cells, appear in the brains of patients with Parkinson's disease and other neurodegenerative diseases. http://www.physorg.com/news150091261.html Medicine & Health Fri, 02 Jan 2009 04:01:01 EST news150091261 Scientists have new information about the complex genetic signature associated with Alzheimer's disease, the leading cause of cognitive decline and dementia in the elderly. The research, published by Cell Press in the January issue of the American Journal of Human Genetics, uses a powerful, high-resolution analysis to look for genes associated with this devastating neurodegenerative disorder. http://www.physorg.com/news149947901.html Medicine & Health Wed, 31 Dec 2008 12:11:41 EST news149947901 A new clinical trial suggests that long-term use of candesartan, a drug currently used to treat hypertension, may significantly reduce the symptoms of genetic heart disease. The related report by Penicka et al, "The effects of candesartan on left ventricular hypertrophy and function in non-obstructive hypertrophic cardiomyopathy: a pilot, randomized study," appears in the January issue of The Journal of Molecular Diagnostics. http://www.physorg.com/news149838893.html Medicine & Health Tue, 30 Dec 2008 05:54:53 EST news149838893 Researchers have discovered that grazing animals such as deer and rabbits are actually helping to spread plant disease - quadrupling its prevalence in some cases - and encouraging an invasion of annual grasses that threaten more than 20 million acres of native grasslands in California. http://www.physorg.com/news149793826.html Biology Mon, 29 Dec 2008 17:23:46 EST news149793826 The emerging field of nutrigenomics, which aims to identify the genetic factors that influence the body's response to diet and studies how the bioactive constituents of food affect gene expression, is explored in a series of provocative, interdisciplinary reports and analyses in the December 2008 Special Issue (Volume 12, number 4) of OMICS: A Journal of Integrative Biology, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com). The issue is available free online at www.liebertpub.com/omi http://www.physorg.com/news149775085.html Medicine & Health Mon, 29 Dec 2008 12:11:25 EST news149775085 According to the latest study by Dr. Ronald Postuma from the Research Institute of the MUHC and Dr. Jacques Montplaisir from the Université de Montréal and the Hôpital du Sacré-Cœur de Montréal, 52.4 per cent of patients with REM sleep behaviour disorder develop a neurodegenerative disease within 12 years following their initial diagnosis. These results will be published on December 24, 2008 in the journal Neurology, the official publication of the American Academy of Neurology. http://www.physorg.com/news149362978.html Medicine & Health Wed, 24 Dec 2008 17:42:58 EST news149362978 (PhysOrg.com) -- When there is a threat of disease during pregnancy, mothers produce less aggressive sons with more efficient immune systems, researchers at The University of Nottingham have discovered. http://www.physorg.com/news149347543.html Medicine & Health Wed, 24 Dec 2008 13:25:43 EST news149347543