http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Gastroesophageal reflux disease (GERD) is defined as the pathological retrograde movement of gastric contents into the esophagus. Various esophageal motility disturbances which may be important in reflux are observed in patients with GERD. The main esophageal motility disorder in these patients is ineffective esophageal motility (IEM). Increased acid clearance time and IEM have been shown to be strongly associated with isolated proximal reflux. However, there are no data that conclusively link motility disorders with isolated distal reflux (IDR). http://www.physorg.com/news179501822.html Medicine & Health Tue, 08 Dec 2009 13:37:34 EST news179501822 New Mayo Clinic research has found that survival rates of patients with Barrett's esophagus, which can be a precursor for esophageal cancer, are no different than the survival rates for the general population. These findings were presented today at the 2009 American College of Gastroenterology (ACG) Annual Meeting in San Diego. http://www.physorg.com/news175787545.html Medicine & Health Mon, 26 Oct 2009 14:52:56 EST news175787545 Researchers have found that early stage cancers of the esophagus can be treated as effectively by less-invasive, organ-sparing endoscopic therapy as compared to more complex surgical removal of the esophagus, according to a Mayo Clinic study published in the September 2009 issue of Gastroenterology. http://www.physorg.com/news171092936.html Medicine & Health Wed, 02 Sep 2009 06:49:24 EST news171092936 Elevated levels of GLI1 (glioma-associated oncogene homolog 1) protein in human breast cancer are associated with unfavorable prognosis and progressive stages of disease. Researchers writing in the open access journal BMC Cancer found increased expression of GLI1 in samples taken from more advanced and less survivable tumors. http://www.physorg.com/news170360080.html Medicine & Health Mon, 24 Aug 2009 19:40:01 EST news170360080 There is minimal data evaluating the prevalence of GERD complications in any United States general population, other than non-Hispanic whites. Presently, it is thought that such complications occur less frequently in African-Americans than in non-Hispanic whites. A research group in Jacksonville, FL investigated the prevalence of reflux esophagitis between non-Hispanic whites and African-Americans. The distribution of esophagitis severity and its complications were equivalent between groups, except for Barrett's esophagus. http://www.physorg.com/news165054465.html Medicine & Health Wed, 24 Jun 2009 09:40:01 EST news165054465 (PhysOrg.com) -- Canadian Light Source (CLS) staff scientist Luca Quaroni and Dr. Alan Casson from the University of Saskatchewan used the synchrotron's infrared microscope to identify tissue afflicted with a condition known as Barrett's Esophagus from chemical fingerprints associated with the disease, which can lead to esophageal cancer. http://www.physorg.com/news163563060.html Medicine & Health Mon, 08 Jun 2009 00:10:01 EST news163563060 Heat generated by radio waves erases most pre-cancerous cells associated with chronic acid reflux, providing an alternative to surgery or the current wait-and-see approach. http://www.physorg.com/news162755092.html Medicine & Health Thu, 28 May 2009 18:45:27 EST news162755092 (AP) -- Zapping away abnormal, precancerous cells in the throat may lower the risk of later developing esophageal cancer, the first major study to test this technique finds. http://www.physorg.com/news162669377.html Medicine & Health Wed, 27 May 2009 18:56:42 EST news162669377 Gastroenterologists at Rush University Medical Center are studying the safety and efficacy of a new system for delivering chemotherapy for patients with esophageal cancer, a rare, but deadly disease that attacks the throat. The unique drug therapy delivers a highly concentrated dose of chemotherapy injected directly on to the hard-to-reach tumors in the esophagus non-surgically. Researchers at Rush are trying to determine if the gel treatment can reduce the size of the cancerous tumors. http://www.physorg.com/news159031314.html Medicine & Health Wed, 15 Apr 2009 16:22:25 EST news159031314 There is growing evidence, say researchers in this week's PLoS Medicine, that people who experience facial flushing after drinking alcohol are at much higher risk of esophageal cancer from alcohol consumption than those who do not. http://www.physorg.com/news157018077.html Medicine & Health Mon, 23 Mar 2009 09:11:38 EST news157018077 Drinking one glass of wine a day may lower the risk of Barrett's Esophagus by 56 percent, according to a new study by the Kaiser Permanente Division of Research in the March issue of Gastroenterology. Barrett's Esophagus is a precursor to esophageal cancer, the nation's fastest growing cancer with an incidence rate that's jumped 500 percent in the last 30 years. http://www.physorg.com/news155188969.html Medicine & Health Mon, 02 Mar 2009 04:03:35 EST news155188969 Metastatic esophageal squamous cell cancer has very poor prognosis. Conventional surgery is considered the most effective treatment, but many cases are inoperable at the time of diagnosis. http://www.physorg.com/news154620008.html Medicine & Health Mon, 23 Feb 2009 14:01:07 EST news154620008 Variations in a common gene pathway may affect esophageal cancer risk, a dangerous and rapidly increasing type of cancer, according to research by scientists at The University of Texas M. D. Anderson Cancer Center. http://www.physorg.com/news145108801.html Medicine & Health Wed, 05 Nov 2008 12:00:01 EST news145108801 Researchers have identified 11 genotypes that may increase esophageal cancer risk, according to research published in the November issue of Cancer Prevention Research, a journal of the American Association for Cancer Research. http://www.physorg.com/news145088334.html Medicine & Health Wed, 05 Nov 2008 06:18:54 EST news145088334 Rhode Island Hospital researchers have identified genetic proteins, also known as biomarkers, capable of distinguishing changes at the microscopic level that can signal a precancerous condition in the esophagus. These markers may help identify patients who are likely to progress to esophageal cancer. This first of its kind study is published in the journal Clinical Cancer Research. http://www.physorg.com/news144946928.html Medicine & Health Mon, 03 Nov 2008 15:02:08 EST news144946928 Expression of Livin in fresh esophageal cancer tissues was detected by immunohistochemistry (IHC), Western blotting and reverse transcriptase-polymerase chain reaction (RT-PCR), VEGF by Its correlation Western blotting and RT-PCR. Livin positivity was also significantly correlated with tumor stages, increasing with tumor progression. Expression of Livin and VEGF increased with the process of esophageal carcinoma. In the fourth clinical stage, expression of Livin and VEGF was the most significant. Expression of Livin was positive correlation with VEGF. Over-expression of Livin and VEGF contributes to the pathogenesis of esophageal carcinoma. http://www.physorg.com/news144496061.html Medicine & Health Wed, 29 Oct 2008 10:47:41 EST news144496061 A study released at the 73rd Annual Scientific Meeting of the American College of Gastroenterology in Orlando found that a new therapeutic treatment, when delivered endoscopically and used in combination with chemotherapy and radiation therapy, improved survival rates in patients with locally advanced esophageal cancer. Cancer of the esophagus often has a poor survival rate. http://www.physorg.com/news142522615.html Medicine & Health Mon, 06 Oct 2008 14:36:55 EST news142522615 Some bacteria may help protect against the development of a type of esophageal cancer, known as adenocarcinoma, according to a new review of the medical literature. These bacteria, which are called Helicobacter pylori, live in the stomachs of humans. http://www.physorg.com/news142481521.html Medicine & Health Mon, 06 Oct 2008 03:12:01 EST news142481521 A new study from researchers in Italy reports that endoscopy may not be necessary in children who show no symptoms after a caustic ingestion. The results demonstrated that the incidence of severe abnormalities of the esophagus in children without any early symptoms is very low and an endoscopy could be avoided. The study appears in the September issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE). http://www.physorg.com/news141645489.html Medicine & Health Fri, 26 Sep 2008 10:58:09 EST news141645489 New research published in the July issue of the Journal of the American College of Surgeons shows elevated plasma DNA is a reliable marker of recurrent esophageal cancer. The study also suggests that plasma DNA levels rise before clinical evidence of cancer recurrence in the majority of patients. http://www.physorg.com/news136195871.html Medicine & Health Fri, 25 Jul 2008 09:11:11 EST news136195871