http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. New figures on deaths from cancer in Europe show a steady decline in mortality between the periods 1990-1994 and 2000-2004. Deaths from all cancers in the European Union (EU) between these two periods fell by nine percent in men and eight percent in women, with a large drop among the middle-aged population. http://www.physorg.com/news178786352.html Medicine & Health Mon, 30 Nov 2009 06:53:12 EST news178786352 Previous studies have indicated that the heparanase (HPA) is correlated with histopathological parameters and poor prognosis of gastric cancers. Although their efficiencies in inhibiting the expression of HPA, the traditional HPA inhibitors may produce nonspecific and undesirable effects. In recent years, genetic approaches targeting HPA have been regarded as a promising alternative. http://www.physorg.com/news178370965.html Medicine & Health Wed, 25 Nov 2009 12:00:01 EST news178370965 Helicobacter pylori has been accepted as an important pathogen inducing gastric cancer. A research group from Taiwan investigated optimal intervention point of Celecoxib, to inhibit H. pylori-associated gastric carcinogenesis in Mongolian gerbils. They found that short-term use resulted in less severe inflammation and inhibited the invasion degree of gastric cancer. Therefore, Celecoxib could be used in the later stages of H. pylori infection to achieve safe and effective chemoprevention of gastric adenocarcinoma. http://www.physorg.com/news175957992.html Medicine & Health Wed, 28 Oct 2009 19:20:02 EST news175957992 There is abundant evidence of an association between Helicobacter pylori chronic infection and gastric cancer. The incidence of gastric cancer is much higher in Japan than Indonesia. A research from Indonesia and Japan found there was a significant difference in the grade and activity of gastric mucosal changes between Indonesian and Japanese H. pylori positive patients. This finding may prove to be an initial step to explain the "Asian paradox." http://www.physorg.com/news175947009.html Medicine & Health Wed, 28 Oct 2009 11:24:23 EST news175947009 An international team of scientists has discovered a new way to classify stomach cancers, and researchers say it may be an important step toward designing more effective treatments and improving long-term survival. http://www.physorg.com/news173681833.html Medicine & Health Fri, 02 Oct 2009 06:20:02 EST news173681833 (PhysOrg.com) -- A study involving a University of Glasgow cancer specialist has found that using Herceptin increases survival rates among those with stomach cancer. http://www.physorg.com/news173103679.html Medicine & Health Fri, 25 Sep 2009 13:40:01 EST news173103679 Although it has been demonstrated that Helicobacter pylori causes gastric cancer, it is still controversial that whether H. pylori eradication therapy is effective in primary prevention of gastric cancer. This is especially important for Yamagata Prefecture, a region of Japan with the second highest incidence of gastric cancer in the world. http://www.physorg.com/news173099928.html Medicine & Health Fri, 25 Sep 2009 12:19:49 EST news173099928 Many studies favor an extended lymphadenectomy at the time of a potentially curative gastrectomy for node-positive gastric cancer, and the risk of long-term death tends to decrease when the number of resected lymph nodes increases to about 25. However, few studies have assessed the relative contribution of the total number of resected lymph nodes to the outcome of patients with node-negative gastric cancer. Further studies are needed to know how the numbers of dissected LNs may affect the survival outcome of patients with node-negative gastric cancer. http://www.physorg.com/news170518037.html Medicine & Health Wed, 26 Aug 2009 15:07:51 EST news170518037 A preliminary evaluation of methylation of two gene promoters in fecal DNA showed promise as a noninvasive method to detect colorectal and gastric cancers, according to a new study published online August 21 in the Journal of the National Cancer Institute. http://www.physorg.com/news170093276.html Medicine & Health Fri, 21 Aug 2009 17:09:09 EST news170093276 Given equivalent results with regards to survival, the impact of anastomotic methods on QOL becomes even more important. There is still no consensus on how to choose a reconstruction method for proximal gastrectomy in patients with upper third gastric cancer. http://www.physorg.com/news166969706.html Medicine & Health Thu, 16 Jul 2009 15:30:04 EST news166969706 A research article to be published on June 21, 2009 in the World Journal of Gastroenterology addresses this question. The research team led by Professor Yan Li from Shengjing Hospital of China Medical University studied the growth inhibitory effects of Alisol B acetat and determined its mechanism of antitumor activity in human gastric cancer cell line SGC7901. http://www.physorg.com/news165488748.html Medicine & Health Mon, 29 Jun 2009 10:40:01 EST news165488748 Current research suggests that levels of gastrin play a key role in the development of Helicobacter-induced stomach cancer. The related report by Takaishi et al, "Gastrin is an essential cofactor for Helicobacter-associated gastric corpus carcinogenesis in C57BL/6 mice," appears in the July 2009 issue of The American Journal of Pathology. http://www.physorg.com/news165045931.html Medicine & Health Wed, 24 Jun 2009 07:05:58 EST news165045931 Checkpoint with forkhead and ring finger (CHFR) is a mitotic stress checkpoint gene whose promoter is frequently methylated in various kinds of cancer. In gastric cancer, CHFR promoter hypermethylation has been reported to lead to chromosome instability (CIN) and genetic instability is one of the hallmarks of human cancer. http://www.physorg.com/news163937995.html Medicine & Health Thu, 11 Jun 2009 11:40:03 EST news163937995 (PhysOrg.com) -- Breast cancer drug Herceptin can extend the lives of patients with incurable stomach cancer by nearly three months, according to an international study involving researchers from the University of Glasgow. http://www.physorg.com/news163089110.html Medicine & Health Mon, 01 Jun 2009 15:32:51 EST news163089110 Heliobacter pylori (H. pylori) infection is considered one of the most important risk factors for stomach (or gastric) cancer with as much as 65% of all cases linked back to the bacteria, although exactly how this occurs is not fully clear. But now researchers in Denmark, Portugal and France, publishing in the journal Clinical Cancer Research, show that H. pylori infection contribution to cancer can be linked to at least three independent molecular pathways, which, when disturbed by infection, lead to mutations in the patients` gastric tissues. http://www.physorg.com/news160991589.html Medicine & Health Fri, 08 May 2009 08:54:22 EST news160991589 A novel, minimally invasive surgical approach to treat stomach cancer has been shown to have advantages that may make it a preferable treatment for some patients. http://www.physorg.com/news159037741.html Medicine & Health Wed, 15 Apr 2009 18:09:33 EST news159037741 Gastric cancer (GC) is one of the most common malignancies in the world with a high incidence and death rate. TNM staging system is used worldwide to predict prognosis and direct therapeutic decisions of patients with GC. However, the prognoses of patients with stage 2 and 3 GC are more heterogeneous and less predictable by staging criteria. http://www.physorg.com/news157633869.html Medicine & Health Mon, 30 Mar 2009 12:12:05 EST news157633869 A research group from Costa Rican evaluated risk factors for gastric cancer in Costa Rican regions with contrasting gastric cancer incidence rates (GCIR). They found that although a pro-inflammatory cytokine genetic profile showed an increased risk for developing gastric cancer (GC), the characteristics of Helicobacter pylori (H. pylori) infection, in particular the status of cagA and vacA genotype distribution seemed to play a major role in GCIR variability in Costa Rica. http://www.physorg.com/news151755622.html Medicine & Health Wed, 21 Jan 2009 10:20:42 EST news151755622 The sequencing of the human genome has opened the door for proteomics by providing a sequence-based framework for mining proteomes. As a result, there is intense interest in applying proteomics to foster a better understanding of cancer processes, develop new biomarkers for diagnosis and early detection of cancer. Gastric carcinoma is one of the most common malignancies worldwide and is the most common cause of cancer-related death in China. The main barrier for improving survival rate is short of useful marker for early diagnosis. http://www.physorg.com/news144495560.html Medicine & Health Wed, 29 Oct 2008 10:39:20 EST news144495560 Primary carcinoma of the stomach is almost always adenocarcinoma or signet ring cell carcinoma and there are few reports of choriocarcinoma or neuroendocrine cell carcinoma. We report a patient with adenocarcinoma of the stomach combined with choriocarcinoma and neuroendocrine cell carcinoma. This is the first reported case of gastric cancer with these three pathological features. http://www.physorg.com/news140953665.html Medicine & Health Thu, 18 Sep 2008 10:47:45 EST news140953665