http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Imagine a huge spool of film containing thousands of sequences of random scenes. Without a talented editor, a screening would have no meaning. http://www.physorg.com/news180024852.html Biology Mon, 14 Dec 2009 14:54:56 EST news180024852 A study published online in this week's Science shows that SPC3649, a breakthrough microRNA-targeted therapy developed by Santaris Pharma A/S, holds promise as a novel treatment for patients infected with the Hepatitis C virus (HCV). http://www.physorg.com/news179073359.html Medicine & Health Thu, 03 Dec 2009 14:36:40 EST news179073359 Researchers at Huntsman Cancer Institute, in collaboration with a worldwide group of physicians and scientists, have discovered a remarkable treatment for a rare, yet debilitating, skin condition. http://www.physorg.com/news178286419.html Medicine & Health Tue, 24 Nov 2009 12:10:01 EST news178286419 (PhysOrg.com) -- UW researchers have successfully used a method called exome sequencing to quickly discover a previously unknown gene responsible for a rare disorder. The finding demonstrates the usefulness of exome sequencing in studying the 7,000 plus rare genetic disorders affecting millions of people. http://www.physorg.com/news177670903.html Medicine & Health Tue, 17 Nov 2009 09:10:04 EST news177670903 (PhysOrg.com) -- With new stem cell lines generated directly from the cells of patients, researchers are able to study how the genetic disorder known as Angelman syndrome develops. http://www.physorg.com/news174759775.html Biology Wed, 14 Oct 2009 17:23:14 EST news174759775 (PhysOrg.com) -- Researchers from the University of Washington and the University of Florida used gene therapy to cure two squirrel monkeys of color blindness - the most common genetic disorder in people. http://www.physorg.com/news172325926.html Medicine & Health Wed, 16 Sep 2009 13:19:09 EST news172325926 (PhysOrg.com) -- Peering at single molecules within an organism that makes its home near thermal vents, Yale University scientists have discovered the structure of a key player in the creation of protein-making factories in humans. http://www.physorg.com/news171812800.html Chemistry Thu, 10 Sep 2009 15:20:02 EST news171812800 (PhysOrg.com) -- Scientists have found new evidence to explain how female insects can influence the father of their offspring, even after mating with up to ten males. A team from the University of Exeter has found that female crickets are able to control the amount of sperm that they store from each mate to select the best father for their young. http://www.physorg.com/news171627059.html Biology Tue, 08 Sep 2009 11:11:41 EST news171627059 A research report featured on the cover of the September 2009 print issue of The FASEB Journal describes how Australian scientists developed a new gene therapy vector that uses the same machinery that viruses use to transport their cargo into our cells. As a result of this achievement, therapeutic DNA can be transferred to a cell's nucleus far more efficiently than in the past, raising hopes for more effective treatment of genetic disorders and some types of cancers. http://www.physorg.com/news170938216.html Biology Mon, 31 Aug 2009 12:00:01 EST news170938216 Genetic researchers at Children's Memorial Hospital, Chicago, are aggressively identifying adult patients who suffer from the genetic disorder, Phenylketonuria (PKU), and are presenting those findings at the 11th International Congress of Inborn Errors of Metabolism in San Diego, August 29 through September 2. http://www.physorg.com/news170498810.html Medicine & Health Wed, 26 Aug 2009 10:00:01 EST news170498810 A specific gene is particularly frequently involved in the development of short stature. Researchers in Heidelberg have now discovered that sequences of genetic material on the X and Y chromosome that regulate this gene are also crucial for growth in children. These gene regulators determine how frequently a gene is copied, thus how effective it is. In many cases, the mutation of one regulatory sequence of the SHOX gene is sufficient to give rise to the full-blown syndrome. http://www.physorg.com/news170420580.html Medicine & Health Tue, 25 Aug 2009 12:30:06 EST news170420580 New research with transgenic mice reveals that a therapy directed at the muscle significantly improves disease symptoms of a genetic disorder characterized by destruction of the neurons that control movement. The study, published by Cell Press in the August 13th issue of the journal Neuron, highlights a promising new treatment for this currently incurable and nontreatable neurodegenerative disorder. http://www.physorg.com/news169299168.html Medicine & Health Wed, 12 Aug 2009 13:00:01 EST news169299168 (PhysOrg.com) -- The weak tendons and fragile bones characteristic of osteogenesis imperfecta, or brittle bone disease, stem from a genetic mutation that causes the incorrect substitution of a single amino acid in the chain of thousands of amino acids making up a collagen molecule, the basic building block of bone and tendon. http://www.physorg.com/news168618876.html Medicine & Health Tue, 04 Aug 2009 15:35:50 EST news168618876 Scientists have a better understanding of what causes an abnormal number of chromosomes in offspring, a condition called aneuploidy that encompasses the most common genetic disorders in humans, such as Down syndrome, and is a leading cause of pregnancy loss. http://www.physorg.com/news167307166.html Medicine & Health Mon, 20 Jul 2009 11:24:38 EST news167307166 Premature ejaculation can be embarrassing, but a new study suggests that it might be a genetic disorder. http://www.physorg.com/news162649525.html Medicine & Health Wed, 27 May 2009 13:25:52 EST news162649525 Brain may win out over brawn as the primary cause of breathing problems in children with a severe form of muscular dystrophy known as Pompe disease. http://www.physorg.com/news162490827.html Medicine & Health Mon, 25 May 2009 17:20:51 EST news162490827 A new tool will help researchers identify the minute changes in DNA patterns that lead to cancer, Huntington's disease and a host of other genetic disorders. The tool was developed at North Carolina State University and translates DNA sequences into graphic images, which allows researchers to distinguish genetic patterns more quickly and efficiently than was historically possible using computers. http://www.physorg.com/news161935232.html Biology Tue, 19 May 2009 07:01:07 EST news161935232 Researchers seeking to understand the causes of a rare genetic lysosomal storage disease, Sanfilippo syndrome type B, were surprised to find protein aggregates, known as neurofibrillary tangles, that are usually seen in Alzheimer's and other forms of dementia, according to a study published May 4 in the Proceedings of the National Academy of Sciences. http://www.physorg.com/news160676472.html Medicine & Health Mon, 04 May 2009 17:22:00 EST news160676472 (AP) -- John Sotos has a theory about why Abraham Lincoln was so tall, why he appeared to have lumps on his lips and even why he had gastrointestinal problems. The 16th president, he contends, had a rare genetic disorder - one that would likely have left him dead of cancer within a year had he not been assassinated. And his bid to prove his theory has posed an ethical and scientific dilemma for a small Philadelphia museum in the year that marks the 200th anniversary of Lincoln's birth. http://www.physorg.com/news159251202.html Medicine & Health Sat, 18 Apr 2009 05:40:58 EST news159251202 For men with Fabry disease, enzyme replacement therapy (ERT) with agalsidase alfa slows deterioration of kidney function, reports a study in the online edition of the Journal of the American Society of Nephrology (JASN). "The results provide further evidence that ERT with agalsidase alfa may slow the progression of kidney disease, provided that ERT is initiated early in the disease process," comments Michael L. West, MD (Dalhousie University, Canada). http://www.physorg.com/news158433132.html Medicine & Health Wed, 08 Apr 2009 18:12:42 EST news158433132 In a new study this week in Nature, researchers at Brandeis University and the MRC Laboratory of Molecular Biology (Cambridge, U.K.) for the first time shed light on a crucial step in the complex process by which human genetic information is transmitted to action in the human cell and frequently at which point genetic disease develops in humans. http://www.physorg.com/news157374235.html Medicine & Health Fri, 27 Mar 2009 12:05:28 EST news157374235 People who suffer an ischemic stroke and also have an abnormality in the heart's electrical cycle are at a higher risk of death within 90 days than people who do not have abnormal electrical activity at the time of emergency treatment, according to new research. http://www.physorg.com/news156751398.html Medicine & Health Fri, 20 Mar 2009 07:04:37 EST news156751398 Researchers at NYU Langone Medical Center may have discovered a new targeted intervention for Barth Syndrome (BTHS). BTHS, a sometimes fatal disease, is a serious genetic disorder occurring predominantly in males that leads to infection or heart failure in childhood. The new study entitled, "Role of calcium-independent phospholipase A2 in the pathogenesis of Barth syndrome", was recently published in the Proceedings of the National Academy of Sciences, shows the benefits of targeted intervention with an iPLA2-VIA inhibitor that prevents a major symptom of the disease- cardiolipin deficiency. http://www.physorg.com/news155227141.html Medicine & Health Mon, 02 Mar 2009 14:42:30 EST news155227141 People with a genetic condition called Williams syndrome are famously gregarious. Scientists, looking carefully at brain function in individuals with Williams syndrome, think they may know why this is so. The researchers at the Stanford University School of Medicine showed that parts of a particular brain region known as the amygdala react more powerfully in Williams syndrome patients than in developmentally normal subjects - or in subjects with delays in development not caused by Williams syndrome - when exposed to facial expressions conveying positive emotions. http://www.physorg.com/news152299739.html Medicine & Health Tue, 27 Jan 2009 17:33:05 EST news152299739 is no cure for spinal muscular atrophy (SMA), a genetic disorder that causes the weakening of muscles and is the leading genetic cause of infant death, but University of Missouri researchers have discovered a new therapeutic target that improves deteriorating skeletal muscle tissue caused by SMA. The new therapy enhanced muscle strength, improved gross motor skills and increased the lifespan in a SMA model. http://www.physorg.com/news150556755.html Medicine & Health Wed, 07 Jan 2009 13:19:15 EST news150556755