http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Blood vessel blockage, a common condition in old age or diabetes, leads to low blood flow and results in low oxygen, which can kill cells and tissues. Such blockages can require amputation resulting in loss of limbs. Now, using mice as their model, researchers at Johns Hopkins have developed therapies that increase blood flow, improve movement and decrease tissue death and the need for amputation. The findings, published online last week in the early edition of the Proceedings of the National Academy of Sciences, hold promise for developing clinical therapies. http://www.physorg.com/news179511321.html Medicine & Health Tue, 08 Dec 2009 16:16:36 EST news179511321 A multi-national research team has discovered that two genetic factors converge to increase the risk of sudden cardiac death. http://www.physorg.com/news174585206.html Medicine & Health Mon, 12 Oct 2009 17:10:04 EST news174585206 (PhysOrg.com) -- In one of the first studies of its kind, an international team of researchers has uncovered a single-letter change in the genetic code that is associated with autism. The finding, published in the October 8 issue of the journal Nature, implicates a neuronal gene not previously tied to the disorder and more broadly, underscores a role for common DNA variation. In addition, the new research highlights two other regions of the genome, which are likely to contain rare genetic differences that may also influence autism risk. http://www.physorg.com/news174140329.html Medicine & Health Wed, 07 Oct 2009 13:19:11 EST news174140329 Once placed into a patient's body, stem cells intended to treat or cure a disease could end up wreaking havoc simply because they are no longer under the control of the clinician. http://www.physorg.com/news162130195.html Biology Thu, 21 May 2009 13:10:32 EST news162130195 Researchers at the Johns Hopkins University School of Medicine, along with an international team of collaborators, have identified common genetic changes associated with blood pressure and hypertension. The study, reporting online next week in Nature Genetics, breaks new ground in understanding blood pressure regulation and may lead to advances in hypertension therapy. http://www.physorg.com/news161182734.html Medicine & Health Sun, 10 May 2009 14:01:16 EST news161182734 MicroRNAs are single-stranded snippets that, not long ago, were given short shrift as genetic junk. Now that studies have shown they regulate genes involved in normal functioning as well as diseases such as cancer, everyone wants to know: What regulates microRNAs? http://www.physorg.com/news160417049.html Medicine & Health Fri, 01 May 2009 17:17:57 EST news160417049 that's all it takes to begin a series of events that lead to metastatic cancer. Now, Johns Hopkins experts have tracked how the cancer process began in 33 men with prostate cancer who died of the disease. Culling information from autopsies, their study points to a set of genetic defects in a single cell that are different for each person's cancer. http://www.physorg.com/news159206962.html Medicine & Health Fri, 17 Apr 2009 17:09:51 EST news159206962 Researchers at the Johns Hopkins University School of Medicine are one gene closer to understanding schizophrenia and related disorders. Reporting in the Jan. 9 issue of the American Journal of Human Genetics, the team describes how a variation in the neuregulin 3 gene influences delusions associated with schizophrenia. http://www.physorg.com/news152897163.html Medicine & Health Tue, 03 Feb 2009 15:27:34 EST news152897163 Digitalis-based drugs like digoxin have been used for centuries to treat patients with irregular heart rhythms and heart failure and are still in use today. In the Dec. 16 issue of the Proceedings of the National Academy of Sciences, researchers at the Johns Hopkins University School of Medicine now report that this same class of drugs may hold new promise as a treatment for cancer. This finding emerged through a search for existing drugs that might slow or stop cancer progression. http://www.physorg.com/news150389159.html Medicine & Health Mon, 05 Jan 2009 14:45:59 EST news150389159