http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. A novel technology involving use of stem cells, developed by Hebrew University of Jerusalem researchers, has been applied to provide better and rapid healing for patients suffering from complicated bone fractures. http://www.physorg.com/news178802935.html Medicine & Health Mon, 30 Nov 2009 11:50:02 EST news178802935 Over the course of a lifetime, the heart pumps some 250 million liters of blood through the body. In the order to do this, the muscle fibers of the heart have to be extremely durable. The research group headed by Dr. Wolfgang Rottbauer, vice chair of the Department of Medicine III at Heidelberg University Hospital (Germany), has discovered a protein that is responsible for the stability of the smallest muscular unit, the sarcomere. http://www.physorg.com/news178369149.html Medicine & Health Wed, 25 Nov 2009 11:10:01 EST news178369149 (PhysOrg.com) -- Even if you never have a heart attack, abnormal blood cholesterol levels may significantly raise your risk of heart failure, according to research reported in Circulation: Journal of the American Heart Association. http://www.physorg.com/news178219940.html Medicine & Health Mon, 23 Nov 2009 18:40:02 EST news178219940 In a new study, researchers report that a class of heart medications called beta-blockers can have a helpful, or harmful, effect on the heart, depending on their molecular activity. http://www.physorg.com/news177941049.html Medicine & Health Fri, 20 Nov 2009 12:20:04 EST news177941049 Heart function significantly improved in children and young adults with single-ventricle congenital heart disease who have had the Fontan operation following treatment with sildenafil, a drug used to treat erectile dysfunction and pulmonary hypertension, say researchers from The Children's Hospital of Philadelphia. http://www.physorg.com/news177772537.html Medicine & Health Wed, 18 Nov 2009 13:40:01 EST news177772537 The largest national stem cell study for heart disease showed the first evidence that transplanting a potent form of adult stem cells into the heart muscle of subjects with severe angina results in less pain and an improved ability to walk. The transplant subjects also experienced fewer deaths than those who didn't receive stem cells. http://www.physorg.com/news177704058.html Medicine & Health Tue, 17 Nov 2009 18:30:02 EST news177704058 A team of U.S., Canadian and Italian scientists led by researchers at Johns Hopkins report evidence from studies in animals and humans supporting a link between Alzheimer's disease and chronic heart failure, two of the 10 leading causes of death in the United States. http://www.physorg.com/news177611563.html Medicine & Health Mon, 16 Nov 2009 16:35:07 EST news177611563 A protein long thought to be a secondary regulator in the heart's response to stressors like hypertension actually appears to be a primary regulator according to researchers from the Center for Translational Medicine at Thomas Jefferson University. The data will be presented in the Late Breaking Science session at the American Heart Associations Scientific Sessions in Orlando, Fla. http://www.physorg.com/news177605812.html Medicine & Health Mon, 16 Nov 2009 15:10:18 EST news177605812 (PhysOrg.com) -- Scientists have grown a piece of heart muscle - and then watched it beat - by using stem cells from a mouse embryo, a big step toward one day repairing damage from heart attacks. http://www.physorg.com/news174839103.html Medicine & Health Thu, 15 Oct 2009 15:26:37 EST news174839103 The source and mechanisms underlying the abnormal heart beats that initiate atrial fibrillation (Afib), the most common type of abnormal heart beat, have not been well determined. However, a group of researchers at the University of Pennsylvania, Philadelphia, has now identified a population of cells that are like pigment producing cells in the skin (melanocytes) in the atria of the heart and pulmonary veins of mice and humans and uncovered evidence in mice that these cells contribute to Afib. http://www.physorg.com/news174591496.html Medicine & Health Mon, 12 Oct 2009 19:00:01 EST news174591496 (PhysOrg.com) -- By mimicking the way embryonic stem cells develop into heart muscle in a lab, Duke University bioengineers believe they have taken an important first step toward growing a living "heart patch" to repair heart tissue damaged by disease. http://www.physorg.com/news174480930.html Medicine & Health Sun, 11 Oct 2009 11:56:10 EST news174480930 University of Washington (UW) researchers have succeeded in engineering human tissue patches free of some problems that have stymied stem-cell repair for damaged hearts. http://www.physorg.com/news174139339.html Medicine & Health Wed, 07 Oct 2009 13:02:58 EST news174139339 'No major role for fish' in the prevention of heart failure; only a possible beneficial effect in those with diabetes http://www.physorg.com/news173516458.html Medicine & Health Wed, 30 Sep 2009 08:01:19 EST news173516458 (PhysOrg.com) -- UA biochemistry researchers apply Nobel Prize technology to develop better diagnostics for heart attacks. Their work also could help predict individual risks of heart disease. http://www.physorg.com/news173109224.html Medicine & Health Fri, 25 Sep 2009 15:20:02 EST news173109224 Compounds related to Viagra, which is already in clinical trials to prevent heart failure, may also counter the disease in a different way, according to a study published online today in the journal Circulation Research. The results hold promise for the design of a new drug class and for its potential use in combination with Viagra or beta blockers. http://www.physorg.com/news173030694.html Medicine & Health Thu, 24 Sep 2009 17:10:28 EST news173030694 Supersaturated oxygen (SSO2) administered during catheter-based treatments for heart attack can significantly reduce heart muscle damage, according to a new study reported in Circulation: Cardiovascular Interventions, a journal of the American Heart Association. http://www.physorg.com/news172253019.html Medicine & Health Tue, 15 Sep 2009 17:30:04 EST news172253019 A team of researchers led by Massachusetts General Hospital (MGH) radiologists has developed a computed-tomography-based protocol that identifies both narrowing of coronary arteries and areas of myocardial ischemia - restricted blood flow to heart muscle tissue - giving a better indication of clinically significant coronary artery disease. Their report appears in the September 15 issue of the Journal of the American College of Cardiology. http://www.physorg.com/news172230356.html Medicine & Health Tue, 15 Sep 2009 11:00:02 EST news172230356 For some patients with acute coronary syndromes, the strategy of immediate intervention at a medical center does not appear to result in differences in outcomes in comparison with an intervention performed the next working day, according to a study in the September 2 issue of JAMA. http://www.physorg.com/news171046665.html Medicine & Health Tue, 01 Sep 2009 18:10:08 EST news171046665 The wider use of reperfusion therapy in patients with heart attack (AMI) can save millions of lives in Europe. Effective reperfusion therapy in an AMI patient can cut the individual risk of dying by half. AMI is caused by a sudden blockage of a coronary artery, one of the vessels supplying the heart muscle with oxygen and nutrients. Effective reperfusion therapy provides a timely and sustainable reopening of the blockage. http://www.physorg.com/news170999938.html Medicine & Health Tue, 01 Sep 2009 04:59:23 EST news170999938 A novel drug that targets a master disease-causing gene can dramatically reduce heart muscle damage after a heart attack and may lead to significantly improved patient outcomes, researchers at the University of New South Wales (UNSW) have shown. http://www.physorg.com/news167651223.html Medicine & Health Fri, 24 Jul 2009 11:30:03 EST news167651223 Researchers appear to have a new way to fix a broken heart. They have devised a method to coax heart muscle cells into reentering the cell cycle, allowing the differentiated adult cells to divide and regenerate healthy heart tissue after a heart attack, according to studies in mice and rats reported in the July 24th issue of the journal Cell, a Cell Press publication. The key ingredient is a growth factor known as neuregulin1 (NRG1 for short), and the researchers suggest that the factor might one day be used to treat failing human hearts. http://www.physorg.com/news167571263.html Medicine & Health Thu, 23 Jul 2009 12:50:04 EST news167571263 It is an amazing sight: What looks like a tiny beating heart is actually a piece of synthetic, gauze-like mesh, barely the size of a fingernail, floating in a Petri dish. And yet it keeps squeezing away, nice and rhythmically. http://www.physorg.com/news167380516.html Medicine & Health Tue, 21 Jul 2009 07:35:45 EST news167380516 In a proof-of-concept study, Mayo Clinic investigators have demonstrated that induced pluripotent stem (iPS) cells can be used to treat heart disease. iPS cells are stem cells converted from adult cells. In this study, the researchers reprogrammed ordinary fibroblasts, cells that contribute to scars such as those resulting from a heart attack, converting them into stem cells that fix heart damage caused by infarction. The findings appear in the current online issue of the journal Circulation. http://www.physorg.com/news167326699.html Medicine & Health Mon, 20 Jul 2009 17:10:04 EST news167326699 (PhysOrg.com) -- Harvard Stem Cell Institute researchers at Massachusetts General Hospital have identified the earliest master human heart stem cell from human embryonic stem cells - ISL1+ progenitors - that give rise to a family of cells that form the essential portions of the human heart. http://www.physorg.com/news165680045.html Medicine & Health Wed, 01 Jul 2009 15:14:48 EST news165680045 A common electrocardiogram (ECG) finding that has largely been considered insignificant may actually signal an increased risk of atrial fibrillation (a chronic heart rhythm disturbance), the future need for a permanent pacemaker and an increased risk for premature death. In their report in the June 24 Journal of the American Medical Association, researchers from Massachusetts General Hospital (MGH) and Boston University School of Medicine describe results of the first large-scale study looking at the significance of a prolonged PR interval in a general population. http://www.physorg.com/news164998759.html Medicine & Health Tue, 23 Jun 2009 22:00:01 EST news164998759 Even while their blood pressures are still normal, overweight male teens may have elevated levels of a hormone known to increase pressures as well as early signs of heart damage, researchers say. http://www.physorg.com/news163075850.html Medicine & Health Mon, 01 Jun 2009 11:51:13 EST news163075850 The injection of bone marrow cells into the heart of patients with chronic myocardial ischemia (reduced blood flow to some areas of the heart) was associated with modest improvements in blood flow and function of the left ventricle, according to a study in the May 20 issue of JAMA. http://www.physorg.com/news161975077.html Medicine & Health Tue, 19 May 2009 18:12:05 EST news161975077 Stem cells play a role in heart muscle rejuvenation by attracting cells from the body that develop into heart muscle cells. They have been successfully used to halt or reverse cardiac injury following heart attack, but not to prevent injury before it occurs. http://www.physorg.com/news161528262.html Biology Thu, 14 May 2009 13:58:22 EST news161528262 An innovative device that acts like a belt to reshape an enlarged, leaky heart valve is providing a minimally invasive treatment option for patients who are too sick for open-heart surgery. According to a Late-Breaking Clinical Trial presented today at the Society for Cardiovascular Angiography and Interventions (SCAI) 32nd Annual Scientific Sessions, the CARILLON Mitral Contour System safely treated leaky mitral valves even in patients with moderate-to-severe heart failure, and was effective in reducing the backward flow of blood from the left ventricle to the left atrium. http://www.physorg.com/news160920965.html Medicine & Health Thu, 07 May 2009 13:16:38 EST news160920965 Twenty percent of American deaths each year are caused by heart attack or angina, sometimes without any warning. http://www.physorg.com/news160059502.html Biology Mon, 27 Apr 2009 13:58:47 EST news160059502