http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Patients with chronic hepatitis C that has been resolved through therapy or immune response may still be able to infect others with the virus. That finding is from a new study in the May issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). http://www.physorg.com/news160656818.html Medicine & Health Mon, 04 May 2009 11:53:52 EST news160656818 The full details about the molecules and mechanisms that underlie the development of autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, remain to be discovered. One compound that may have a role in alleviating these conditions is quinoline-3-carboxamide, which is currently being tested in various clinical trials. In this week's PLoS Biology, researchers from Lund University, Sweden, the University of Munster in Germany, and the company Active Biotech AB, identify a molecular target for quinoline compounds. http://www.physorg.com/news160129369.html Biology Tue, 28 Apr 2009 09:23:20 EST news160129369 Flu vaccine delivered through skin patches containing microneedles has proven just as effective at preventing influenza in mice as intramuscular, hypodermic flu immunization. A team of researchers at Emory University and the Georgia Institute of Technology believes the new microneedle skin patch method of delivering flu vaccine could improve overall seasonal vaccination coverage in people because of decreased pain, increased convenience, lower cost and simpler logistics over conventional hypodermic immunization. http://www.physorg.com/news160072120.html Medicine & Health Mon, 27 Apr 2009 17:29:04 EST news160072120 The bacteria responsible for chronic infections in cystic fibrosis patients use one of the sugars on the germs' surface to start building a structure that helps the microbes resist efforts to kill them, new research shows. http://www.physorg.com/news159537486.html Biology Tue, 21 Apr 2009 12:58:29 EST news159537486 A Michigan State University researcher has developed a working vaccine for a strain of E. coli that kills 2 million to 3 million children each year in the developing world. http://www.physorg.com/news158951048.html Medicine & Health Tue, 14 Apr 2009 18:04:31 EST news158951048 Deficiency in vitamin D has been widely regarded as contributing to autoimmune disease, but a review appearing in Autoimmunity Reviews explains that low levels of vitamin D in patients with autoimmune disease may be a result rather than a cause of disease and that supplementing with vitamin D may actually exacerbate autoimmune disease. http://www.physorg.com/news158425579.html Medicine & Health Wed, 08 Apr 2009 16:06:48 EST news158425579 Scientists at the University of Melbourne have discovered the local action of immune cells in the skin, which could improve treatment of viral skin infections. http://www.physorg.com/news158328856.html Medicine & Health Tue, 07 Apr 2009 13:14:44 EST news158328856 For years, researchers and physicians have known that infants' immune systems do not respond well to certain vaccines, thus the need for additional boosters as children develop. Now, in a new study from the University of Missouri, one researcher has found an explanation for that poor response. In the study, the MU scientist found evidence that the immune systems of newborns might require some time after birth to mature to a point where the benefits of vaccines can be fully realized. http://www.physorg.com/news157817036.html Medicine & Health Wed, 01 Apr 2009 15:04:22 EST news157817036 Cholera patients also infected with parasitic intestinal worms have a significantly reduced immune response to the cholera toxin, according to a report published March 31st in the open-access journal PLoS Neglected Tropical Diseases. Results of the study from a collaborative team led by researchers at Massachusetts General Hospital (MGH) and the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B) suggest that parasitic infection could reduce immunity to future cholera infection and may compromise the effectiveness of cholera vaccines. http://www.physorg.com/news157705370.html Medicine & Health Tue, 31 Mar 2009 08:06:41 EST news157705370 Migration of colonic lamina propria fibroblasts (CLPF) plays an important role during the progression of fibrosis and fistulae in Crohn's disease. Transforming growth factor- beta (TGF- beta) is involved in the regulation of cell migration, cell differentiation, extracellular matrix deposition, and immune responses. Since the regulation of migration and differentiation of intestinal fibroblasts is an important mechanism during intestinal wound healing and fibrosis, it is important to investigate the effect of TGF- beta 1 on these processes and on fibronectin (FN) and FN isoform production. http://www.physorg.com/news157637926.html Medicine & Health Mon, 30 Mar 2009 13:19:20 EST news157637926 Researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and at Ghent University in Ghent, Belgium, have identified a new role for certain lung cells in the immune response to airborne allergens. Many foreign substances, called antigens, are inhaled daily, but the lungs have mechanisms that usually prevent people from making unwanted immune responses to these materials. http://www.physorg.com/news157633193.html Medicine & Health Mon, 30 Mar 2009 12:00:37 EST news157633193 New research suggests that monoclonal antibody therapy of cancer can be improved to be much more powerful than it is today, says a researcher at Georgetown University Medical Center's Lombardi Comprehensive Cancer Center in the March 21 issue of the Lancet. http://www.physorg.com/news156772110.html Medicine & Health Fri, 20 Mar 2009 13:29:23 EST news156772110 Over the past decade various pieces of the puzzle how signal transmission controls immunity have been coming together. Now, in Cell an international team reports a paradigm shift in the regulation of immune response. Their results show that interaction with a linear ubiquitin chain is crucial for nuclear factor kappa B activation. Their findings may also contribute towards structure-based drug design to target the defective NF-κB pathway in diseases such as cancer, inflammation and immunodeficiency. http://www.physorg.com/news156695912.html Biology Thu, 19 Mar 2009 15:39:06 EST news156695912 Researchers at the University of Pittsburgh School of Medicine have begun testing a vaccine that might be able to prevent colon cancer in people at high risk for developing the disease. If shown to be effective, it might spare patients the risk and inconvenience of repeated invasive surveillance tests, such as colonoscopy, that are now necessary to spot and remove precancerous polyps. http://www.physorg.com/news156689071.html Medicine & Health Thu, 19 Mar 2009 13:45:00 EST news156689071 (PhysOrg.com) -- Instead of a dreaded injection with a needle, someday getting vaccinated against disease may be as pleasant as drinking a yogurt smoothie. http://www.physorg.com/news156528415.html Medicine & Health Tue, 17 Mar 2009 17:07:16 EST news156528415 Dendritic cells are essential to the body's immune defenses. Now, Ludwig-Maximilians-Universitaet Muenchen (Germany) researchers show that they also have to protect the body from itself: They help to identify any immune cells that attack the body's own tissue and need to be destroyed or pacified. http://www.physorg.com/news156451710.html Medicine & Health Mon, 16 Mar 2009 19:49:00 EST news156451710 (PhysOrg.com) -- For 25 years, researchers have tried and failed to develop an HIV vaccine, primarily by focusing on a small number of engineered "super antibodies" to fend off the virus before it takes hold. So far, these magic bullet antibodies have proved impossible to produce in people. Now, in research to be published March 15 online by Nature, scientists at The Rockefeller University have laid out a new approach. They have identified a diverse team of antibodies in "slow-progressing" HIV patients whose coordinated pack hunting knocks down the virus just as well as their super-antibody cousins fighting solo. http://www.physorg.com/news156346918.html Medicine & Health Sun, 15 Mar 2009 14:42:37 EST news156346918 (PhysOrg.com) -- Researchers at the Johns Hopkins Bloomberg School of Public Health have for the first time identified a molecular pathway that triggers an immune response in multiple mosquito species capable of stopping the development of Plasmodium falciparum-the parasite that causes malaria in humans. http://www.physorg.com/news156160228.html Medicine & Health Fri, 13 Mar 2009 10:51:04 EST news156160228 Women with certain gene variations appear to be protected against cervical cancer, according to a study led by scientists at Albert Einstein College of Medicine of Yeshiva University and reported in Clinical Cancer Research. Knowing whether or not women have these genetic variants could help physicians to better tailor treatment strategies. http://www.physorg.com/news156098381.html Medicine & Health Thu, 12 Mar 2009 17:40:12 EST news156098381 Researchers have revealed a direct relationship between two specific antibodies and the severity of Alzheimer's disease symptoms, raising hopes that a diagnostic blood test for the devastating disorder is within reach. http://www.physorg.com/news156007002.html Medicine & Health Wed, 11 Mar 2009 16:17:40 EST news156007002 Inflammation, the body's earliest response to damage or infection, can aid the healing process and trigger an immune response against invading pathogens. But inflammation gone awry can also undermine health, as in diseases such as rheumatoid arthritis or asthma. http://www.physorg.com/news155993656.html Biology Wed, 11 Mar 2009 12:35:33 EST news155993656 Administration of a tissue-cultured smallpox vaccine showed signs of an effective vaccine response with no serious adverse events, according to a study in the March 11 issue of JAMA. http://www.physorg.com/news155938566.html Medicine & Health Tue, 10 Mar 2009 21:16:29 EST news155938566 An immune system response that is critical to the first stages of fighting off viruses and harmful bacteria comes from an entirely different direction than most scientists had thought, according to a finding by researchers at the Duke University Medical Center. http://www.physorg.com/news155137707.html Medicine & Health Sun, 01 Mar 2009 13:48:55 EST news155137707 A new article appearing in the March 2009 issue of the Journal of Leukocyte Biology may lead to improvements in the efficacy of the current tuberculosis vaccine. Specifically, a team of Italian researchers discovered a new role for type I interferon, in which it improves the ability of dendritic cells to stimulate an immune response against the bacterium known to cause tuberculosis. The researchers speculate that type I interferon may give the current vaccine the "boost" necessary to elicit a protective immunity against the mycobacterium tuberculosis. http://www.physorg.com/news154874438.html Biology Thu, 26 Feb 2009 12:41:32 EST news154874438 A study led by researchers at the University of Illinois reveals how a cellular protein recognizes an invading virus and alerts the body to the infection. http://www.physorg.com/news154278336.html Biology Thu, 19 Feb 2009 15:06:15 EST news154278336 (PhysOrg.com) -- The way in which bacteria that cause bacterial meningitis mimic human cells to evade the body's innate immune system has been revealed by researchers at the University of Oxford and Imperial College London. http://www.physorg.com/news154186118.html Medicine & Health Wed, 18 Feb 2009 13:29:23 EST news154186118 Platelets, tiny and relatively uncharted tenants of the bloodstream known mostly for their role in blood clotting, turn out to also rally sustained immune system inflammatory responses that play a critical role in organ transplant rejection, according to a new report from Johns Hopkins scientists. http://www.physorg.com/news154118265.html Medicine & Health Tue, 17 Feb 2009 18:39:04 EST news154118265 Colorado State University researchers have discovered that mosquitoes that transmit deadly viruses such as dengue avoid becoming ill by mounting an immediate, potent immune response. Because their immune system does not eliminate the virus, however, they are able to pass it on to a new victim. http://www.physorg.com/news153736384.html Chemistry Fri, 13 Feb 2009 08:33:50 EST news153736384 A century-old drug that failed in its original intent to treat tuberculosis but has worked well as an antileprosy medicine now holds new promise as a potential therapy for multiple sclerosis and other autoimmune diseases. http://www.physorg.com/news152560827.html Medicine & Health Fri, 30 Jan 2009 18:00:58 EST news152560827 For the first time, a team of researchers at the University of Pennsylvania School of Veterinary Medicine have imaged in real time the body's immune response to a parasitic infection in the brain. http://www.physorg.com/news152371179.html Biology Wed, 28 Jan 2009 13:20:06 EST news152371179