http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. New research has identified biomarkers associated with inflammation and progression in joint erosion in individuals with early rheumatoid arthritis (RA), according to the results of a new study presented at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark. The researchers suggest a potential role for these biomarkers in the monitoring of ongoing disease activity through assessing inflammation and joint destruction, two important targets for the treatment of early RA. http://www.physorg.com/news164279589.html Medicine & Health Mon, 15 Jun 2009 11:00:01 EST news164279589 Three new studies have individually shown the anti-TNF (tumour necrosis factor) therapy etanercept to be effective, with a good safety profile, in children under four years of age with juvenile idiopathic arthritis (JIA), and associated with improved Health-Related Quality of Life (HRQoL) in a substantial proportion of children with JIA. http://www.physorg.com/news164034519.html Medicine & Health Fri, 12 Jun 2009 14:08:52 EST news164034519 Researchers at the University of California, San Diego School of Medicine have developed the first mouse model for auto-inflammatory diseases, disorders that involve the over-activation of the body's innate, primitive immune system. Their study, published early on-line in Cell Immunity on June 4, suggests that the innate - not adaptive - immune system drives auto-inflammatory diseases. The findings could open new therapeutic directions for research into disorders such as gout or inflammatory bowel disease. http://www.physorg.com/news163343219.html Medicine & Health Thu, 04 Jun 2009 14:07:50 EST news163343219 (PhysOrg.com) -- UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders, some of which increase risk for several types of cancer. http://www.physorg.com/news163044358.html Medicine & Health Mon, 01 Jun 2009 03:06:22 EST news163044358 Using a controlled diet study with human volunteers, researchers may have teased out a biological basis for the increased inflammation observed due to humans' shift in their consumption of omega fatty acids. http://www.physorg.com/news162837855.html Biology Fri, 29 May 2009 17:44:44 EST news162837855 Immigration officials held a cancer patient for four hours before they allowed him to enter the USA because one of his cancer drugs caused his fingerprints to disappear. His oncologist is now advising all cancer patients who are being treated with the commonly used drug, capecitabine, to carry a doctor's letter with them if they want to travel to the USA. http://www.physorg.com/news162626394.html Medicine & Health Wed, 27 May 2009 07:00:34 EST news162626394 A team of researchers has found an association between breast cancer survival and two proteins that, when present in the blood in high levels, are indicators of inflammation. Using data from the Health, Eating, Activity and Lifestyle (HEAL) study sponsored by the National Cancer Institute, part of the National Institutes of Health, the researchers found that breast cancer patients with elevated levels of C-reactive protein (CRP) and serum amyloid A (SAA) were approximately two to three times more likely to die sooner or have their cancer return than those patients who had lower levels of these proteins, regardless of the patient's age, tumor stage, race, body mass index, or history of previous cardiovascular issues. The results of this study were published online, May 26, 2009, in the Journal of Clinical Oncology. http://www.physorg.com/news162573606.html Medicine & Health Tue, 26 May 2009 16:21:40 EST news162573606 There are several risk factors for the development of Alzheimer's disease and vascular dementia. Based on an increasing number of studies linking these risk factors with Vitamin D deficiency, an article in the current issue of the Journal of Alzheimer's Disease (May 2009) by William B. Grant, PhD of the Sunlight, Nutrition, and Health Research Center (SUNARC) suggests that further investigation of possible direct or indirect linkages between Vitamin D and these dementias is needed. http://www.physorg.com/news162562458.html Medicine & Health Tue, 26 May 2009 13:14:53 EST news162562458 Researchers at Iowa State University have found that increased expression of a form of cytochrome P-450 (CYP4B1) is a key marker of inhibition of colitis in mice by caffeic acid, an anti-inflammatory antioxidant compound widely distributed in foods. http://www.physorg.com/news162553970.html Medicine & Health Tue, 26 May 2009 10:53:31 EST news162553970 The colorectal cancer is thought to be resulted from a combination of environmental factors, diet, lifestyle, chronic inflammation and accumulation of specific genetic alterations. The pathogenesis and development of colorectal cancer involve multi-genes and multi-steps. TSPAN1 (GenBank Accession No. AF065388) is a new member of TM4SF located at chromosome 1 p34.1. It encodes a 241 amino acid protein. TSPAN1 was reported as a tumor-related gene recently. http://www.physorg.com/news162213544.html Medicine & Health Fri, 22 May 2009 12:19:27 EST news162213544 Researchers from the Peninsula Medical School in Exeter have synthesized a new molecule which releases hydrogen sulfide (H2S) - the gas that gives rotten eggs their characteristic smell and which has recently been found to be produced naturally in the body - and discovered that it could in time lead to a range of new, safer and effective anti-inflammatory drugs for human use. http://www.physorg.com/news162106769.html Biology Thu, 21 May 2009 06:40:14 EST news162106769 (PhysOrg.com) -- Osteoporosis and periodontitis are common diseases whose sufferers must cope with weakness, injury and reduced function as they lose bone more quickly than it is formed. While the mechanism of bone destruction in these diseases is understood, scientists have had less information about how bone formation is impaired. http://www.physorg.com/news161949438.html Medicine & Health Tue, 19 May 2009 10:58:28 EST news161949438 Research by Peter Barnes (Imperial College, London) and colleagues may explain the effectiveness of common treatments for allergic inflammation and may point the way to targets for new treatments for allergic diseases, according to a study published in this week's open-access journal PLoS Medicine. http://www.physorg.com/news161933211.html Medicine & Health Tue, 19 May 2009 06:27:34 EST news161933211 Scientists at Singapore's Institute of Molecular and Cell Biology (IMCB), under the Agency for Science, Technology and Research (A*STAR), have identified the protein, WIP1, as the molecular "brake" that curbs severe inflammation in the body. http://www.physorg.com/news161518107.html Biology Thu, 14 May 2009 11:09:15 EST news161518107 A potential vaccine for Alzheimer's disease also has been shown in mice to slow the weakening of muscles associated with inclusion body myositis, a disorder that affects the elderly. http://www.physorg.com/news161439371.html Medicine & Health Wed, 13 May 2009 13:16:42 EST news161439371 University of Florida researchers have learned more about how smallpox conducts its deadly business - discoveries that may reveal as much about the human immune system as they do about one of the world's most feared pathogens. http://www.physorg.com/news161281299.html Medicine & Health Mon, 11 May 2009 17:21:57 EST news161281299 Heliobacter pylori (H. pylori) infection is considered one of the most important risk factors for stomach (or gastric) cancer with as much as 65% of all cases linked back to the bacteria, although exactly how this occurs is not fully clear. But now researchers in Denmark, Portugal and France, publishing in the journal Clinical Cancer Research, show that H. pylori infection contribution to cancer can be linked to at least three independent molecular pathways, which, when disturbed by infection, lead to mutations in the patients` gastric tissues. http://www.physorg.com/news160991589.html Medicine & Health Fri, 08 May 2009 08:54:22 EST news160991589 Chronic inflammation, which is at the root of multiple diseases, links periodontal disease to increased incidence of cardiovascular disease. http://www.physorg.com/news160752916.html Medicine & Health Tue, 05 May 2009 14:35:36 EST news160752916 Spondylarthritis (SpA) represents a group of arthritidies that share clinical features such as inflammatory back pain and inflammation at sites where tendons attach to bone. It includes ankylosing spondylitis (AS), psoriatic arthritis, inflammatory bowel-disease-related arthritis, reactive arthritis (ReA) and undifferentiated spondylarthritides (uSpA). http://www.physorg.com/news160323071.html Medicine & Health Thu, 30 Apr 2009 15:11:32 EST news160323071 Researchers at the University of Massachusetts Medical School (UMMS) report today on a novel approach to the delivery of small bits of genetic material in order to silence genes using "RNA interference" -and in the process, discovered a potent method of suppressing inflammation in mice similar to what occurs in a range of human diseases. http://www.physorg.com/news160229724.html Medicine & Health Wed, 29 Apr 2009 13:15:58 EST news160229724 New research from Lucile Packard Children's Hospital and the Stanford University School of Medicine is helping physicians unravel the cause of a deadly and mysterious bowel disease that strikes medically fragile newborn babies. The findings could lead to a better understanding of the disease and its medical management, and also shed light on the causes of sepsis, a major killer of children and young adults. http://www.physorg.com/news160029655.html Medicine & Health Mon, 27 Apr 2009 05:41:21 EST news160029655 Eating just one and a half servings of tart cherries could significantly boost antioxidant activity in the body, according to new University of Michigan research reported at the 2009 Experimental Biology meeting in New Orleans.1 In the study, healthy adults who ate a cup and a half of frozen cherries had increased levels of antioxidants, specifically five different anthocyanins - the natural antioxidants that give cherries their red color. http://www.physorg.com/news159373446.html Medicine & Health Sun, 19 Apr 2009 15:24:32 EST news159373446 New studies in pregnant mice using antibodies against fetal brains made by the mothers of autistic children show that immune cells can cross the placenta and trigger neurobehavioral changes similar to autism in the mouse pups. http://www.physorg.com/news159207023.html Medicine & Health Fri, 17 Apr 2009 17:10:49 EST news159207023 Corticosteroids are powerful drugs used to treat inflammatory conditions such as asthma and other chronic diseases which has made them among the most widely prescribed drugs. Although the anti-inflammatory drugs offer swift relief to the patient, they can carry with them serious side effects. For example, the inflammatory steroids used to treat a child's asthma, but can stunt the child's growth over time. Similarly, adult treatment of Addison's disease, which President John F. Kennedy endured, can lead to the development of diabetes and hypertension. http://www.physorg.com/news159191534.html Medicine & Health Fri, 17 Apr 2009 12:52:31 EST news159191534 The prevalence of a certain form of drug-resistant bacteria, called multidrug-resistant gram-negative (MDRGN) organisms, far surpassed that of two other common antimicrobial-resistant infections in long-term care facilities, according to a study conducted by researchers at Hebrew SeniorLife's Institute for Aging Research. http://www.physorg.com/news158583927.html Medicine & Health Fri, 10 Apr 2009 12:06:14 EST news158583927 Michelle Stevens first noticed the red, blotchy patches on her toddler's feet after he started walking. Every time Noah walked outdoors in their grassy backyard, the blotches appeared. http://www.physorg.com/news158435472.html Medicine & Health Wed, 08 Apr 2009 18:51:29 EST news158435472 Deficiency in vitamin D has been widely regarded as contributing to autoimmune disease, but a review appearing in Autoimmunity Reviews explains that low levels of vitamin D in patients with autoimmune disease may be a result rather than a cause of disease and that supplementing with vitamin D may actually exacerbate autoimmune disease. http://www.physorg.com/news158425579.html Medicine & Health Wed, 08 Apr 2009 16:06:48 EST news158425579 (PhysOrg.com) -- According to a recent study in the Archives of Internal Medicine, 75 percent of Americans do not get enough Vitamin D. Researchers have found that the deficiency may negatively impact immune function and cardiovascular health and increase cancer risk. Now, a University of Missouri nutritional sciences researcher has found that vitamin D deficiency is associated with inflammation, a negative response of the immune system, in healthy women. http://www.physorg.com/news158251047.html Medicine & Health Mon, 06 Apr 2009 15:38:05 EST news158251047 (PhysOrg.com) -- Scientists at the University of Glasgow have made a significant breakthrough in the treatment of Sleeping Sickness, otherwise known as Human African Trypanosomasis. http://www.physorg.com/news157985628.html Medicine & Health Fri, 03 Apr 2009 13:54:07 EST news157985628 Researchers at the University of Illinois report that IDO, an enzyme found throughout the body and long suspected of playing a role in depression, is in fact essential to the onset of depressive symptoms sparked by chronic inflammation. http://www.physorg.com/news157737755.html Medicine & Health Tue, 31 Mar 2009 17:03:47 EST news157737755