http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. (PhysOrg.com) -- Finding and treating a tumor without disturbing normal tissue presents challenges - sometimes the most effective therapies can be invasive and harsh. http://www.physorg.com/news178804691.html Chemistry Mon, 30 Nov 2009 11:58:49 EST news178804691 Researchers from the University of Michigan determined that only 663,000 of the approximately 3.9 million Americans with hepatitis C virus (HCV) infection received antiviral therapy between 2002 and 2007. Treatment rates appear to be declining, in part because only half of the patients know they are infected. If this disturbing trend continues, by 2030 less than 15% of liver-related deaths from HCV will be prevented by antiviral therapy. This study, the first to analyze nationwide practice patterns for HCV treatment, is published in the December issue of Hepatology, a journal of the American Association for the Study of Liver Diseases. http://www.physorg.com/news178264993.html Medicine & Health Tue, 24 Nov 2009 06:50:01 EST news178264993 In patients with unresectable (unable to be removed by surgery) liver cancer, an interventional radiology procedure called triple-drug transcatheter arterial chemoemobolization (TACE) followed by a liver transplant may significantly increase a patient's chance of long-term survival, according to a study published in the December issue of the American Journal of Roentgenology. http://www.physorg.com/news177945840.html Medicine & Health Fri, 20 Nov 2009 13:24:39 EST news177945840 (PhysOrg.com) -- A toxin produced by mold on nuts and grains can cause liver cancer if consumed in large quantities. UC Irvine researchers for the first time have discovered what triggers the toxin to form, which could lead to methods of limiting its production. http://www.physorg.com/news175352760.html Chemistry Wed, 21 Oct 2009 14:06:47 EST news175352760 A recent study maps the pathway that leads from infection with Hepatitis B and C virus (HBV and HCV) to chronic hepatitis and liver cancer and proposes a new therapeutic strategy for treating liver diseases with chronic inflammation. The research, published by Cell Press in the October issue of the journal Cancer Cell, describes a signaling pathway that can be beneficial during liver regeneration, but can lead to chronic hepatitis and severe liver damage when chronically activated. The research was performed in the Department of Pathology, Institutes of Clinical Pathology and Neuropathology at the University Hospital in Zurich. http://www.physorg.com/news173968463.html Medicine & Health Mon, 05 Oct 2009 14:10:08 EST news173968463 (PhysOrg.com) -- Viruses like Hepatitis C proliferate by tricking cellular machinery into manufacturing the parts for duplicate viral particles. http://www.physorg.com/news173549327.html Chemistry Wed, 30 Sep 2009 17:09:14 EST news173549327 Penn State College of Medicine researchers, in collaboration with colleagues at the University of Southern California, have taken an important step in understanding the role of stem cells in development of liver cancer. Using a unique approach that involves study of individual cells, the team, led by C. Bart Rountree, M.D., has demonstrated for the first time a population of cancer stem cells in the liver prior to tumor formation. The research, published in the journal Stem Cells, shows a potential link between liver stem cells and liver cancer. http://www.physorg.com/news172424170.html Medicine & Health Thu, 17 Sep 2009 16:50:02 EST news172424170 A 20-year follow-up study revealed a dramatic drop in liver cancer cases among 6- to 19-year-olds who were vaccinated for the hepatitis B virus at birth, according to a study published online September 16 in the Journal of the National Cancer Institute. http://www.physorg.com/news172337405.html Medicine & Health Wed, 16 Sep 2009 16:35:12 EST news172337405 The three treatment combinations for clearing the most common form of the hepatitis C virus work equally well with similar side effects, UT Southwestern Medical Center researchers and their colleagues in 13 other institutions have found. Hepatitis C affects nearly 4 million Americans and leads to cirrhosis and liver cancer but can be arrested permanently in many patients. http://www.physorg.com/news168857842.html Medicine & Health Fri, 07 Aug 2009 09:57:45 EST news168857842 A new study investigated the effectiveness of S-adenosylmethionine (SAMe) in the prevention and treatment of hepatocellular carcinoma (HCC) or primary liver cancer. SAMe, a widely available nutritional supplement, with little known side effects, was found to be effective in preventing the formation of HCC in rats. However, high enough levels of SAMe were not attainable to successfully treat established HCC. The findings are available in the August issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases. http://www.physorg.com/news168181552.html Medicine & Health Thu, 30 Jul 2009 14:21:07 EST news168181552 Two genes may contribute to chemotherapy resistance in drugs like 5-fluorouracil, which is used in liver cancer treatment, according to Virginia Commonwealth University Massey Cancer Center researchers. http://www.physorg.com/news167325348.html Medicine & Health Mon, 20 Jul 2009 16:16:45 EST news167325348 (AP) -- A hospital in New York state is notifying about 2,800 patients of possible exposure to hepatitis C after learning that a former employee is suspected of exposing nearly 6,000 patients in Colorado to the disease. http://www.physorg.com/news166941080.html Medicine & Health Thu, 16 Jul 2009 05:31:58 EST news166941080 Scientists at Singapore's Bioprocessing Technology Institute (BTI) have made a novel discovery about how the gene, "Fas-apoptosis inhibitory molecule" (FAIM), protects both immune and liver cells from apoptosis, or programmed cell death. http://www.physorg.com/news165825938.html Medicine & Health Fri, 03 Jul 2009 07:46:05 EST news165825938 Diets high in protein and cholesterol are associated with a higher risk of hospitalization or death due to cirrhosis or liver cancer, while diets high in carbohydrates are associated with a lower risk. These findings are in the July issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). http://www.physorg.com/news165671019.html Medicine & Health Wed, 01 Jul 2009 12:44:01 EST news165671019 Ohio State University cancer researchers have used computational and genomic methods to identify possible anti-cancer agents that may block a particular kind of tumor behavior. The agents target multiple genes associated with that behavior at one time. http://www.physorg.com/news164547226.html Medicine & Health Thu, 18 Jun 2009 12:50:02 EST news164547226 In a multi-center trial led by a Saint Louis University researcher, investigators found that a new combination therapy of daily consensus interferon and ribavirin helps some hepatitis C patients who have not responded to previous treatment. The findings, published in the June issue of Hepatology, offer a new option for hepatitis C patients, and may be effective even for those patients with factors that make their condition difficult to treat. http://www.physorg.com/news164360551.html Medicine & Health Tue, 16 Jun 2009 09:10:01 EST news164360551 Liver cancer is one of the most fatal human malignancies and the third most frequent cause of tumor-related death, about half a million people globally each year. The current methods used to monitor such high-risk groups include ultrasound scans and a test for the presence of a single protein in the blood called alpha-fetoprotein. It is a good indicator of advanced liver cancer, but less able to detect early disease. So it is the most impotent thing is find the changes of biomarker combinations in the early period of diseases, control the key gene in the initial stage of disease and reverse the development of disease. http://www.physorg.com/news164278973.html Medicine & Health Mon, 15 Jun 2009 10:03:12 EST news164278973 In a study comparing two strains of mice, one susceptible to developing cancer and the other not, researchers found that a high-fat diet predisposed the cancer-susceptible strain to liver cancer, and that by switching to a low-fat diet early in the experiment, the same high-risk mice avoided the malignancy. The switched mice were lean rather than obese and had healthy livers at the end of the study. http://www.physorg.com/news163989266.html Medicine & Health Fri, 12 Jun 2009 06:50:02 EST news163989266 Researchers at Nationwide Children's Hospital and Johns Hopkins University have discovered that delivering a small molecule that is highly expressed in normal tissues but lost in diseased cells can result in tumor suppression. http://www.physorg.com/news163942021.html Medicine & Health Thu, 11 Jun 2009 12:28:26 EST news163942021 A protein abundant in embryonic stem cells is now shown to be important in cancer, and offers a possible new target for drug development, report researchers from the Stem Cell Program at Children's Hospital Boston. http://www.physorg.com/news163081825.html Medicine & Health Mon, 01 Jun 2009 13:33:06 EST news163081825 Leicester consultant surgeon who has developed a pioneering technique using microwaves to destroy liver tumours has treated more than 100 patients in the UK and other patients are now being treated internationally. http://www.physorg.com/news161347636.html Medicine & Health Tue, 12 May 2009 11:47:49 EST news161347636 The commonly used prescription statin drugs may have a protective effect in the prevention of liver cancer and lead to a reduction in the need for gallbladder removals, according to two studies published in Gastroenterology. As millions of Americans use statins each day to help lower their cholesterol and risk of heart disease, researchers are learning of the beneficial effects these drugs may have on gastrointestinal disorders. Gastroenterology is the official journal of the American Gastroenterological Association (AGA) Institute. http://www.physorg.com/news160756410.html Medicine & Health Tue, 05 May 2009 15:33:58 EST news160756410 Women with a history of hypothyroidism face a significantly higher risk of developing liver cancer, according to a new study in the May issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). http://www.physorg.com/news160656514.html Medicine & Health Mon, 04 May 2009 11:48:48 EST news160656514 In a new study, a therapeutic agent called sorafenib dramatically improved the condition of rats with portal hypertension. The drug is already approved in several countries for treatment of kidney and liver cancer, and it may be time to consider it for patients suffering from advanced portal hypertension, the authors suggest. Their findings are in the April issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). http://www.physorg.com/news157810010.html Medicine & Health Wed, 01 Apr 2009 13:07:50 EST news157810010 Alcohol-related deaths in England and Wales are twice as high among people born in Scotland or Ireland compared with the rest of the population, a study has shown. http://www.physorg.com/news156713753.html Medicine & Health Thu, 19 Mar 2009 20:36:39 EST news156713753 Liver cancer in patients whose only risk factor is metabolic syndrome has distinct forms and structures compared to other liver tumors. These findings are in the March issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). http://www.physorg.com/news154789424.html Medicine & Health Wed, 25 Feb 2009 13:04:46 EST news154789424 A new study examining data on incidence trends, mortality rates and survival rates from the National Cancer Institute's Surveillance Epidemiology and End Results (SEER) cancer registries indicates that the incidence of liver cancer in the United States tripled between 1975 and 2005. http://www.physorg.com/news154191005.html Medicine & Health Wed, 18 Feb 2009 14:50:45 EST news154191005 (PhysOrg.com) -- Virginia Commonwealth University researchers have identified a gene that plays a key role in regulating liver cancer progression, a discovery that could one day lead to new targeted therapeutic strategies to fight the highly aggressive disease. http://www.physorg.com/news154109542.html Medicine & Health Tue, 17 Feb 2009 16:12:55 EST news154109542 Scientists have identified a genetic signature that is remarkably effective at predicting the prognosis of an aggressive liver cancer in children. The research, published by Cell Press in the December issue of the journal Cancer Cell, may lead to better treatments for pediatric liver cancers. http://www.physorg.com/news147965816.html Medicine & Health Mon, 08 Dec 2008 13:36:56 EST news147965816 A new Canadian study comparing cancer rates of liver transplant patients to those of the general population has found that transplant recipients face increased risks of developing cancer, especially non-Hodgkin's lymphoma and colorectal cancer. Risks were more pronounced during the first year of follow-up and among younger transplant recipients. These findings are published in the November issue of Liver Transplantation, a journal by John Wiley & Sons. http://www.physorg.com/news144946240.html Medicine & Health Mon, 03 Nov 2008 14:50:40 EST news144946240