http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. (PhysOrg.com) -- An international team of researchers has identified a new method for selectively killing metastatic melanoma cells, which may lead to new areas for drug development in melanoma - a cancer that is highly resistant to current treatment strategies. http://www.physorg.com/news168523956.html Medicine & Health Mon, 03 Aug 2009 13:40:03 EST news168523956 Recent research has uncovered an unexpected vulnerability in deadly melanoma cells that, when exploited, can cause the cancer cells to turn against themselves. The study, published by Cell Press in the August issue of the journal Cancer Cell, identifies a new target for development of future therapeutics aimed at selectively eliminating this aggressive skin cancer which is characterized by a notoriously high rate of metastasis and treatment-resistance. http://www.physorg.com/news168523563.html Medicine & Health Mon, 03 Aug 2009 13:06:23 EST news168523563 Hoag Memorial Hospital Presbyterian today announced promising data from a clinical study showing patient-specific cancer vaccines derived from patients' own cancer cells and immune cells were well tolerated and resulted in impressive long-term survival rates in patients with metastatic melanoma whose disease had been minimized by other therapies. http://www.physorg.com/news168017006.html Medicine & Health Tue, 28 Jul 2009 16:23:50 EST news168017006 Melanoma is the most serious form of skin cancer, diagnosed in more than 50,000 new patients in the United States annually. While the rate of incidences continues to rise, survival rate has not improved and the race is on to find the genetic and cellular changes driving melanoma and to devise new means of detection and treatment. In a study published online in Genome Research, scientists have mapped chemical modifications of DNA in the melanoma genome, finding new markers that will help develop more effective treatment strategies to fight this disease. http://www.physorg.com/news165509319.html Medicine & Health Mon, 29 Jun 2009 15:49:20 EST news165509319 A protein called Mcl-1 plays a critical role in melanoma cell resistance to a form of apoptosis called anoikis, according to research published this week in Molecular Cancer Research. http://www.physorg.com/news159081716.html Medicine & Health Thu, 16 Apr 2009 06:22:39 EST news159081716 Researchers at the Babraham Institute and the University of Catanzaro "Magna Graecia", Italy, co-ordinating an international network of scientists and clinicians from Europe, the USA and Japan, have identified new mechanisms through which the immune system recognises and responds to tumours like melanomas. This discovery may offer therapeutic approaches for tackling metastatic melanoma, an aggressive form of skin cancer responsible for around 2,000 deaths in the UK each year. http://www.physorg.com/news158570124.html Medicine & Health Fri, 10 Apr 2009 08:15:58 EST news158570124 Scientists have long wondered how melanoma cells travel from primary tumors on the surface of the skin to the brain, liver and lungs, where they become more aggressive, resistant to therapy, and deadly. Now, scientists from NYU Langone Medical Center have identified the possible culprit -a short strand of RNA called microRNA (miRNA) that is over-expressed in metastatic melanoma cell lines and tissues. http://www.physorg.com/news153407237.html Medicine & Health Mon, 09 Feb 2009 13:07:45 EST news153407237 Hollow gold nanospheres equipped with a targeting peptide find melanoma cells, penetrate them deeply, and then cook the tumor when bathed with near-infrared light, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reported in the Feb. 1 issue of Clinical Cancer Research. http://www.physorg.com/news152772851.html Nanotechnology Mon, 02 Feb 2009 04:55:02 EST news152772851 (PhysOrg.com) -- One of the most promising new ideas about the causes of cancer, known as the cancer stem-cell model, must be reassessed because it is based largely on evidence from a laboratory test that is surprisingly flawed when applied to some cancers, University of Michigan researchers have concluded. http://www.physorg.com/news147532400.html Medicine & Health Wed, 03 Dec 2008 13:13:20 EST news147532400