http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. A chemical cousin of the common antibiotic tetracycline might be useful in treating spinal muscular atrophy (SMA), a currently incurable disease that is the leading genetic cause of death in infants. This is the finding of a research collaboration involving Adrian Krainer, Ph.D., of Cold Spring Harbor Laboratory (CSHL) and scientists from Paratek Pharmaceuticals and Rosalind Franklin University of Medicine and Science. http://www.physorg.com/news176569921.html Medicine & Health Wed, 04 Nov 2009 15:30:02 EST news176569921 New research with transgenic mice reveals that a therapy directed at the muscle significantly improves disease symptoms of a genetic disorder characterized by destruction of the neurons that control movement. The study, published by Cell Press in the August 13th issue of the journal Neuron, highlights a promising new treatment for this currently incurable and nontreatable neurodegenerative disorder. http://www.physorg.com/news169299168.html Medicine & Health Wed, 12 Aug 2009 13:00:01 EST news169299168 Spinal Muscular Atrophy is the second-leading cause of infant mortality in the world. http://www.physorg.com/news167923556.html Medicine & Health Mon, 27 Jul 2009 14:26:49 EST news167923556 Researchers have found a potential new treatment for the common problem of muscle atrophy. http://www.physorg.com/news163938470.html Medicine & Health Thu, 11 Jun 2009 11:28:29 EST news163938470 Caused by a mutation of the SMN gene, spinal muscular atrophy (SMA) is an infantile and juvenile neurodegenerative disorder where motor neuron loss causes progressive paralysis. A new study published in the open access journal BMC Medicine details the first research focused on human muscle tissue atrophied due to a genetic condition, and sheds light on two distinct mechanisms at work in different forms of SMA. http://www.physorg.com/news158303237.html Medicine & Health Tue, 07 Apr 2009 06:07:49 EST news158303237 is no cure for spinal muscular atrophy (SMA), a genetic disorder that causes the weakening of muscles and is the leading genetic cause of infant death, but University of Missouri researchers have discovered a new therapeutic target that improves deteriorating skeletal muscle tissue caused by SMA. The new therapy enhanced muscle strength, improved gross motor skills and increased the lifespan in a SMA model. http://www.physorg.com/news150556755.html Medicine & Health Wed, 07 Jan 2009 13:19:15 EST news150556755 (PhysOrg.com) -- Spinal muscular atrophy, a neurodegenerative disorder that causes the weakening of muscles, is the leading cause of infant death and occurs in 1 in 6,000 live births. While trans-splicing (a form of molecular therapy) has had impressive results as a treatment for spinal muscular atrophy in cell-based models of disease, scientists have been unable to translate the therapy to the human body. A University of Missouri researcher has developed a strategy that will enhance trans-splicing activity and bring it closer to being used in the clinical setting. http://www.physorg.com/news148575832.html Medicine & Health Mon, 15 Dec 2008 15:03:52 EST news148575832 Carrier screening for spinal muscular atrophy (SMA) -a serious genetic disease affecting approximately 1 in 10,000 infants that causes progressive muscle weakness and death -should be made available to all families, according to a new practice guideline issued by the American College of Medical Genetics (ACMG). The statement appears in the November 2008 issue of Genetics in Medicine, the official peer-reviewed journal of the American College of Medical Genetics. In the past, tests to identify carriers of the gene responsible for SMA have generally been offered only to people with a family history of the disease. http://www.physorg.com/news148063945.html Medicine & Health Tue, 09 Dec 2008 16:52:25 EST news148063945