http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Long-term survivors of testicular cancer who were treated with cisplatin-based chemotherapy had more severe side effects, including neurological side effects and Raynaud-like phenomena, than men who were not treated with chemotherapy, according to a new study published online November 25 in the Journal of the National Cancer Institute. http://www.physorg.com/news178393701.html Medicine & Health Wed, 25 Nov 2009 21:50:01 EST news178393701 Researchers have found evidence of a statistically significant survival benefit from adjuvant tamoxifen among patients whose estrogen receptor (ER)-positive tumors had high levels of phosphorylation of ER-alpha; at serine-118 (ER-alpha S118-P), according to a brief communication published online November 25 in the Journal of the National Cancer Institute. http://www.physorg.com/news178393693.html Medicine & Health Wed, 25 Nov 2009 19:50:01 EST news178393693 In clinical trials for cancer, it is standard for clinicians rather than patients to report adverse symptom side effects from treatments, such as nausea and fatigue. At present, patient self-reporting, although important, is not a well studied source of this information. A new longitudinal study from researchers at Memorial Sloan-Kettering Cancer Center finds that while clinicians' and patients' reporting of treatment side effects are very different from each other, together they provide a more complete, clinically meaningful picture of the treatment experience. http://www.physorg.com/news177702169.html Medicine & Health Tue, 17 Nov 2009 18:50:03 EST news177702169 Risk of bladder cancer for smokers has increased since the mid-1990s, with a risk progressively increasing to a level five times higher among current smokers in New Hampshire than that among nonsmokers in 2001-2004, according to a new study published online November 16 in the Journal of the National Cancer Institute. Furthermore, researchers found that among individuals who smoked the same total number of cigarettes over their lifetime, smoking fewer cigarettes per day for more years may be more harmful than smoking more cigarettes per day for fewer years. http://www.physorg.com/news177620245.html Medicine & Health Mon, 16 Nov 2009 22:30:01 EST news177620245 The small-molecule inhibitor nutlin-3 may be a viable treatment option for neuroblastoma patients with wild-type p53 activity, according to a new study published online November 10 in the Journal of the National Cancer Institute. http://www.physorg.com/news177098545.html Medicine & Health Tue, 10 Nov 2009 18:30:01 EST news177098545 Medications frequently given to cancer patients to reduce their risk of anemia are associated with an increased risk of deep vein thrombosis or pulmonary embolism, according to new research led by Dawn Hershman, M.D, M.S., co-director of the breast cancer program at the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian Hospital/Columbia University Medical Center. The findings will be published online on Nov. 10, 2009 in the Journal of the National Cancer Institute (ahead of the Dec. 2, 2009 print edition). http://www.physorg.com/news177097215.html Medicine & Health Tue, 10 Nov 2009 17:50:01 EST news177097215 Human papillomavirus (HPV) DNA testing with cytology triage is more sensitive than conventional cytology screening for detecting cervical lesions, according to a new study published online November 9 in the Journal of the National Cancer Institute. Cytology triage in HPV-positive women can improve specificity. http://www.physorg.com/news177059142.html Medicine & Health Tue, 10 Nov 2009 08:10:02 EST news177059142 Overall survival (OS) may be a reasonable primary endpoint when the median survival postprogession (SSP) is less than 6 months, but it is too high a hurdle when SPP is longer than 12 months, according to a new study published online November 9 in the Journal of the National Cancer Institute. http://www.physorg.com/news177059223.html Medicine & Health Tue, 10 Nov 2009 07:40:01 EST news177059223 People living in volcanic areas may be at a higher risk for thyroid cancer, according to a new study published online November 5 in the Journal of the National Cancer Institute. http://www.physorg.com/news176662195.html Medicine & Health Thu, 05 Nov 2009 17:30:02 EST news176662195 After a steady increase of invasive breast cancer cases in Spanish women during the 1980s and 1990s, incidence rates abruptly declined starting in 2001 -a trend most likely explained by a period effect linked to screening saturation, according to a new study published online October 26 in the Journal of the national cancer institute. http://www.physorg.com/news175795020.html Medicine & Health Mon, 26 Oct 2009 17:30:01 EST news175795020 Jewish survivors of World War II who were potentially exposed to the Holocaust are at a higher risk for cancer occurrence, according to a new study published online October 26 in the Journal of the National Cancer Institute. http://www.physorg.com/news175793717.html Medicine & Health Mon, 26 Oct 2009 17:00:09 EST news175793717 A relative utility curve is a simple method to evaluate risk prediction in a medical decision-making framework, according to a commentary published online October 20 in the Journal of the National Cancer Institute. http://www.physorg.com/news175276082.html Medicine & Health Tue, 20 Oct 2009 17:20:02 EST news175276082 Unexpectedly, inflammation markers do not appear to be involved with the chemopreventative effect of aspirin on colorectal adenomas, according to a brief communication published online October 12 in the Journal of the National Cancer Institute. http://www.physorg.com/news174585295.html Medicine & Health Mon, 12 Oct 2009 17:40:02 EST news174585295 For the first time, researchers at Fred Hutchinson Cancer Research Center have demonstrated that it is possible to successfully recruit and retain a large number of adolescent smokers from the general population into a smoking intervention study and, through personalized, proactive telephone counseling, significantly impact rates of six-month continuous quitting. These findings, by Arthur V. Peterson Jr., Ph.D., Kathleen A. Kealey and colleagues, are reported in a pair of papers in the Oct. 12 "Advance Access" online edition of the Journal of the National Cancer Institute. http://www.physorg.com/news174584678.html Medicine & Health Mon, 12 Oct 2009 16:46:01 EST news174584678 Women with increased levels of Müllerian inhibiting substance (MIS), best known for regulating in utero sexual differentiation in boys, may be at a greater risk for breast cancer, according to a new study published online October 9 in the http://www.physorg.com/news174325601.html Medicine & Health Fri, 09 Oct 2009 17:10:02 EST news174325601 Researchers propose a more efficient system using archived specimens for the evaluation of prognostic and predictive biomarkers in a new commentary published online October 8 in the Journal of the National Cancer Institute. http://www.physorg.com/news174238334.html Medicine & Health Thu, 08 Oct 2009 16:32:43 EST news174238334 Investing in some colorectal cancer screening programs could cut future, more expensive treatment costs in half, according to a new study published online September 24 in the Journal of the National Cancer Institute. The only screening program found not to be cost-saving was colonoscopy. http://www.physorg.com/news173030915.html Medicine & Health Thu, 24 Sep 2009 17:20:02 EST news173030915 The Merkel cell polyomavirus (MCPyV) is the only human polyomavirus known to be associated with a rare skin cancer, known as Merkel cell carcinoma, according to a new study published online September 23 in the Journal of the National Cancer Institute. http://www.physorg.com/news172944590.html Medicine & Health Wed, 23 Sep 2009 17:12:12 EST news172944590 The polyclonality of BRAF mutations in melanocytic nevi suggests that mutation of BRAF may not be an initial event in melanocyte transformation, according to a new brief communication published online September 14 in the Journal of the National Cancer Institute. http://www.physorg.com/news172166610.html Medicine & Health Mon, 14 Sep 2009 18:10:02 EST news172166610 A new study from Harvard School of Public Health (HSPH) and Brigham and Women's Hospital researchers has found a strong association between the common sexually transmitted infection, Trichomonas vaginalis, and risk of advanced and lethal prostate cancer in men. http://www.physorg.com/news171733197.html Medicine & Health Wed, 09 Sep 2009 16:40:33 EST news171733197 A third of the previously identified single-nucleotide polymorphisms, or SNPs, associated with prostate cancer in men of European or African ancestry were also associated with prostate cancer in a Japanese population, according to a new study published online September 2 in the Journal of the National Cancer Institute. http://www.physorg.com/news171136383.html Medicine & Health Wed, 02 Sep 2009 20:30:01 EST news171136383 The introduction of prostate-antigen screening, or PSA, has resulted in over 1 million additional men over the last 23 years being diagnosed and treated for prostate cancer -most of whom were likely overdiagnosed, researchers reported in a new study published online August 31 in the Journal of the National Cancer Institute. http://www.physorg.com/news170960468.html Medicine & Health Mon, 31 Aug 2009 18:20:02 EST news170960468 About three-quarters of women newly diagnosed with breast cancer have a friend or family member with them at their first visit with a surgeon. And that person plays a significant role in the patient's decision of what type of surgery to have, according to a new study from the University of Michigan Comprehensive Cancer Center. http://www.physorg.com/news170956792.html Medicine & Health Mon, 31 Aug 2009 17:05:12 EST news170956792 Breast cancer detection rates and sensitivity were higher, but so were false-positive rates, among mammography centers that offered clinical breast examination in addition to mammography, according to new study published online August 31 in the Journal of the National Cancer Institute. http://www.physorg.com/news170954852.html Medicine & Health Mon, 31 Aug 2009 16:40:01 EST news170954852 The racial disparity in prostate cancer stage at diagnosis has decreased statistically significantly over time, according to a brief communication published online August 27 in the Journal of the National Cancer Institute. http://www.physorg.com/news170609354.html Medicine & Health Thu, 27 Aug 2009 16:30:01 EST news170609354 Manipulating the functions of melanosomes--the organelles in pigment-producing cells--may enhance the activity of anticancer drugs used against melanoma, according to a new study published online August 24 in the Journal of the National Cancer Institute. http://www.physorg.com/news170351264.html Medicine & Health Tue, 25 Aug 2009 02:50:01 EST news170351264 Training methods for surgeons who perform breast cancer sentinel lymph node resection were found to be effective in almost 97% of surgeons assessed, according to a new study published online August 24 in the Journal of the National Cancer Institute. http://www.physorg.com/news170350491.html Medicine & Health Mon, 24 Aug 2009 20:40:02 EST news170350491 A preliminary evaluation of methylation of two gene promoters in fecal DNA showed promise as a noninvasive method to detect colorectal and gastric cancers, according to a new study published online August 21 in the Journal of the National Cancer Institute. http://www.physorg.com/news170093276.html Medicine & Health Fri, 21 Aug 2009 17:09:09 EST news170093276 A public survey conducted in Europe found that the vast majority of people overestimate the life-saving benefits of breast and prostate cancer screening, according to a new study published online August 12 in the Journal of the National Cancer Institute. http://www.physorg.com/news169212575.html Medicine & Health Tue, 11 Aug 2009 12:40:01 EST news169212575 From a health-care system perspective, it may be more efficient to use the drug cetuximab only in colorectal cancer patients whose tumors have a wild-type KRAS gene, according to a study published online August 7 in the Journal of the National Cancer Institute. http://www.physorg.com/news168929397.html Medicine & Health Sat, 08 Aug 2009 05:50:31 EST news168929397