http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. In the December 2009 issue of the Journal of General Physiology, Moss et al. report a comprehensive investigation employing Förster resonance energy transfer (FRET) to study the {gamma}-amino acid (GABA) transporter GAT1, a member of the family that includes transporters for neurotransmitters dopamine (DAT), serotonin (SERT), norepinephrine (NET) and glycine (GlyT). http://www.physorg.com/news178803576.html Medicine & Health Mon, 30 Nov 2009 11:50:01 EST news178803576 The small-molecule inhibitor nutlin-3 may be a viable treatment option for neuroblastoma patients with wild-type p53 activity, according to a new study published online November 10 in the Journal of the National Cancer Institute. http://www.physorg.com/news177098545.html Medicine & Health Tue, 10 Nov 2009 18:30:01 EST news177098545 Survivors of the childhood cancer neuroblastoma are eight times more likely to have chronic health conditions, less likely to be married, and more likely to have lower incomes than their siblings, according to a study published online July 31 in the Journal of the National Cancer Institute. http://www.physorg.com/news168281693.html Medicine & Health Fri, 31 Jul 2009 18:30:02 EST news168281693 Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer cells to proliferate, migrate and invade surrounding tissues. The study was published in the journal Cancer Research on June 15. http://www.physorg.com/news167659729.html Medicine & Health Fri, 24 Jul 2009 13:40:01 EST news167659729 Two new studies from The Children's Hospital of Philadelphia advance the search for genetic events that result in neuroblastoma, a puzzling, often-deadly type of childhood cancer. http://www.physorg.com/news164464334.html Medicine & Health Wed, 17 Jun 2009 13:32:47 EST news164464334 Virginia Commonwealth University researchers have identified a gene that may play a key role in regulating tumor progression in neuroblastoma, a form of cancer usually found in young children. Scientists hope the finding could lead to an effective therapy to inhibit the expression of this gene. http://www.physorg.com/news163089207.html Medicine & Health Mon, 01 Jun 2009 15:33:47 EST news163089207 A phase III study has shown that adding an antibody-based therapy that harnesses the body's immune system resulted in a 20 percent increase in the number of children living disease-free for at least two years with neuroblastoma. Neuroblastoma, a hard-to-treat cancer arising from nervous system cells, is responsible for 15 percent of cancer-related deaths in children. The researchers reported their findings - the first to show that immunotherapy could be effective against childhood cancer - online May 14, 2009 on the American Society of Clinical Oncology website in advance of presentation June 2. http://www.physorg.com/news161546544.html Medicine & Health Thu, 14 May 2009 19:03:19 EST news161546544 Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have found a new drug that restricts the growth of neuroblastoma, a childhood brain cancer. The pre-clinical study was presented today in the plenary session at the 22nd annual meeting of the American Society of Pediatric Hematology/Oncology. http://www.physorg.com/news159728519.html Medicine & Health Thu, 23 Apr 2009 18:03:17 EST news159728519 In a new study, published in the May issue of Elsevier's Experimental Neurology, scientists at the University of British Columbia have discovered that drugs commonly used to treat ulcers have significant neuroprotective properties, which appear to be enhanced when used in combination with ibuprofen, a widely used anti-inflammatory drug. http://www.physorg.com/news159648436.html Medicine & Health Wed, 22 Apr 2009 19:48:03 EST news159648436 Results from a new study identify a biomarker that may be useful for predicting the outcome of treatment for neuroblastoma, the most common cancer in young children. The research, published by Cell Press in the April 7th issue of the journal Cancer Cell, also provides new information about the molecular signals that are involved in the progression of this often devastating pediatric cancer. http://www.physorg.com/news158245194.html Medicine & Health Mon, 06 Apr 2009 14:00:25 EST news158245194 After identifying an apparent population of cancer stem cells for neuroblastoma, researchers successfully used a reprogrammed herpes virus to block tumor formation in mice by targeting and killing the cells. http://www.physorg.com/news151737767.html Medicine & Health Wed, 21 Jan 2009 05:23:22 EST news151737767 The compound, α-difluoromethylornithine or DFMO, targets the activity of a specific enzyme and, even in very limited doses, is effective in protecting against the malignancy in animal models. The study was published in the January 15, 2009 issue of the journal, Cancer Research (Volume 69, Issue 2). http://www.physorg.com/news151249783.html Medicine & Health Thu, 15 Jan 2009 13:49:43 EST news151249783 A new study reveals critical molecular mechanisms associated with the development and progression of human neuroblastoma, the most common cancer in young children. The research, published by Cell Press in the January 6th issue of the journal Cancer Cell, may lead to development of future strategies for treatment of this aggressive and unpredictable cancer. http://www.physorg.com/news150382749.html Medicine & Health Mon, 05 Jan 2009 12:59:09 EST news150382749