http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. When cells accumulate excessive errors in the proteins they produce, apoptosis is activated, that is to say, a cell suicide programme; however, beforehand the cells attempt to rectify the problem through a number of rescue responses. Scientists know only the general outline of the mechanisms behind cellular "stress responses", the interactions between them and the molecular components involved. http://www.physorg.com/news180273234.html Chemistry Thu, 17 Dec 2009 12:20:04 EST news180273234 MIT and Boston University researchers have discovered that the drug hydroxyurea kills bacteria by inducing them to produce molecules toxic to themselves - a conclusion that raises the possibility of finding new antibiotics that use similar mechanisms. http://www.physorg.com/news179674100.html Biology Thu, 10 Dec 2009 13:29:28 EST news179674100 (PhysOrg.com) -- Cisplatin is one of the most powerful and effective drugs for treating a wide variety of cancers, but serious side effects ultimately limit the drug's use and effectiveness. Now, however, researchers have developed a nanoparticulate formulation of cisplatin that may be able to eliminate or reduce platinum-associated toxicity while boosting cisplatin's tumor-killing activity. http://www.physorg.com/news176060990.html Nanotechnology Thu, 29 Oct 2009 18:50:19 EST news176060990 Theresa M. Reineke, associate professor of chemistry in the College of Science, and colleagues in her lab at Virginia Tech and at the University of Cincinnati have developed a new molecule that can travel into cells, deliver genetic cargo, and packs a beacon so scientists can follow its movements in living systems. http://www.physorg.com/news174063755.html Chemistry Tue, 06 Oct 2009 16:03:10 EST news174063755 Imagine a surgical patient on a blood-thinning drug who starts bleeding more than expected, and an antidote that works immediately - because the blood thinner and antidote were designed to work together. Researchers at Duke University Medical Center have engineered a way to do this for an entire, versatile class of drugs called aptamers and published their findings in Nature Medicine. http://www.physorg.com/news173881624.html Medicine & Health Sun, 04 Oct 2009 13:28:50 EST news173881624 (PhysOrg.com) -- Small pieces of nucleic acid known as short interfering RNAs, or siRNAs, can turn off the production of specific proteins, a property that makes them one of the more promising new classes of anticancer drugs in development. Indeed, at least two siRNA-based anticancer therapies, both delivered to tumors in nanoparticles, have begun human clinical trials. http://www.physorg.com/news172951531.html Nanotechnology Wed, 23 Sep 2009 19:06:33 EST news172951531 (PhysOrg.com) -- John Spence, a physicist at Arizona State University, is a longtime user of the Advanced Light Source at Lawrence Berkeley National Laboratory, where he has contributed to major advances in lensless imaging. It`s a particularly apt propensity for someone who works with x-rays, since they can`t be focused with ordinary lenses. http://www.physorg.com/news168620492.html Physics Tue, 04 Aug 2009 16:20:01 EST news168620492 Laboratory studies at Kansas State University and the work of a K-State researcher are making headway in the effort to control the pandemic H1N1 virus. http://www.physorg.com/news168172647.html Medicine & Health Thu, 30 Jul 2009 11:46:34 EST news168172647 John Spence, a physicist at Arizona State University, is a longtime user of the Advanced Light Source at Lawrence Berkeley National Laboratory, where he has contributed to major advances in lensless imaging. It's a particularly apt propensity for someone who works with x-rays, since they can't be focused with ordinary lenses. http://www.physorg.com/news168092880.html Physics Wed, 29 Jul 2009 13:28:29 EST news168092880 An iconic photograph (http://img.timeinc.net/time/80days/images/530228.jpg) of Nobel laureates Drs. Francis Crick and James Watson show the pair discussing with a rigid model of the famous double helix. http://www.physorg.com/news166717469.html Biology Mon, 13 Jul 2009 15:25:05 EST news166717469 (PhysOrg.com) -- Self-assembling and self-organizing systems are the Holy Grails of nanotechnology, but nature has been producing such systems for millions of years. A team of scientists has taken a unique look at how thousands of bacterial membrane proteins are able to assemble into clusters that direct cell movement to select chemicals in their environment. Their results provide valuable insight into how complex periodic patterns in biological systems can be generated and repaired. http://www.physorg.com/news166199996.html Biology Tue, 07 Jul 2009 15:43:15 EST news166199996 Scientists at The University of Manchester have developed an experiment that sheds new and fascinating light on how life on Earth might have begun. http://www.physorg.com/news161456485.html Chemistry Wed, 13 May 2009 18:02:05 EST news161456485 Biomedical engineers have developed a new type of probe that allows them to visualize single ribonucleic acid (RNA) molecules within live cells more easily than existing methods. The tool will help scientists learn more about how RNA operates within living cells. http://www.physorg.com/news158245779.html Chemistry Mon, 06 Apr 2009 14:10:04 EST news158245779 Scientists from the Virginia Bioinformatics Institute (VBI) at Virginia Tech, the University of Maryland School of Medicine, and the University of Louisville have revealed that genes for a specific type of molecular secretion system in Rickettsia, a structure that is linked in many cases to virulence, have been conserved over many years of evolution. http://www.physorg.com/news156059574.html Biology Thu, 12 Mar 2009 06:54:01 EST news156059574 Investigators at Northwestern University have found that packing small interfering RNA (siRNA) molecules onto the surface of a gold nanoparticle can protect siRNAs from degradation and increase their ability to regulate genes involved in cancer. As a result of this discovery, cancer researchers have at their disposal a relatively straightforward method of delivering these potent gene-regulating agents into targeted cells. http://www.physorg.com/news154627849.html Nanotechnology Mon, 23 Feb 2009 16:11:37 EST news154627849 A simple, chemical materials model may lead to a better understanding of the structure and organization of the cell according to a Penn State researcher. http://www.physorg.com/news153830013.html Chemistry Sat, 14 Feb 2009 10:35:16 EST news153830013 (PhysOrg.com) -- Anyone who has ever battled a stuck zipper knows it's a good idea to see what's stuck, where and how badly -- and then to pull hard. A Cornell research team's experiments involve the "unzipping" of single DNA molecules. By mapping the hiccups, stoppages and forces along the way, they have gained new insight into how genes are packed and expressed within cells. http://www.physorg.com/news152382840.html Biology Wed, 28 Jan 2009 16:34:20 EST news152382840 (PhysOrg.com) -- One of the grand goals in nanotechnology is to develop a single microfluidic device that integrates all of the components needed to perform polymerase chain reaction (PCR)-based nucleic acid analyses. Experts predict that such a device would enable researchers to develop rapid assays for cancer and other life-threatening diseases while a patient is in the doctor`s office. http://www.physorg.com/news151345628.html Nanotechnology Fri, 16 Jan 2009 16:27:08 EST news151345628 Drug molecules seldom act simply on one protein but on protein complexes and networks. A deeper understanding of these 'cooperative assemblies' should lead to better targeting of drugs http://www.physorg.com/news143713408.html Biology Mon, 20 Oct 2008 09:23:28 EST news143713408