http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. (PhysOrg.com) -- When a dividing cell duplicates its genetic material, a molecular machine called a sliding clamp travels along the DNA double helix, tethering the proteins that perform the replication. Researchers from the laboratory of Rockefeller University`s Michael O'Donnell, a Howard Hughes Medical Institute investigator, have discovered a small molecule that stops the sliding clamp in its tracks. The finding will enable scientists to better study the proteins that duplicate DNA, and may ultimately provide a platform for developing improved antibiotics. http://www.physorg.com/news143731311.html Biology Mon, 20 Oct 2008 14:21:51 EST news143731311 Northeastern University scientists have discovered a new and unique DNA binding property of a protein in E. coli. Penny J. Beuning, Assistant Professor in the Department of Chemistry and Chemical Biology, spent the last two years researching double and single-stranded DNA binding of E. coli DNA polymerase III alpha protein and notes that her findings have potential for developing a new antibacterial target. http://www.physorg.com/news136566772.html Chemistry Tue, 29 Jul 2008 16:12:52 EST news136566772