http://www.physorg.com/ en-us Physorg.com internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Almost a century after it was discovered in fruit flies with notches in their wings, the Notch signalling pathway may come to play an important role in the recovery from heart attacks. In a study published today in Circulation Research, scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, are the first to prove that this signalling pathway targets heart muscle cells and thus reveal its crucial role in heart development and repair. http://www.physorg.com/news179662276.html Medicine & Health Thu, 10 Dec 2009 10:48:16 EST news179662276 (PhysOrg.com) -- For years, health conscious people have been taking antioxidants to reduce the levels of reactive oxygen in their blood and prevent the DNA damage done by free radicals, which are the result of oxidative stress. But could excessive use of antioxidants deplete our immune systems? http://www.physorg.com/news173002874.html Biology Thu, 24 Sep 2009 09:21:41 EST news173002874 Scientists discovered a gene - called AP2gamma - crucial for the neural development of the visual cortex, in a discovery that can have implications for the therapeutics of neural regeneration as well as provide new clues about how the brain evolved into higher sophistication in mammals. The article will come out in the journal Nature Neuroscience today. http://www.physorg.com/news172139390.html Medicine & Health Mon, 14 Sep 2009 09:40:01 EST news172139390 (PhysOrg.com) -- Accumulation of the synaptic protein alpha-synuclein, resulting in the formation of aggregates called Lewy bodies in the brain, is a hallmark of Parkinson's and other related neurodegenerative diseases. This pathology appears to spread throughout the brain as the disease progresses. Now, researchers at the University of California, San Diego School of Medicine and Konkuk University in Seoul, South Korea, have described how this mechanism works. http://www.physorg.com/news167934383.html Medicine & Health Mon, 27 Jul 2009 18:20:02 EST news167934383 To determine if guided fat (adipose) precursor cells (APCs) could improve nerve regeneration and functional recovery, researchers at the University of Pittsburgh (USA) used biodegradable nerve guides to transplant APCs into the injured peripheral nerves of laboratory rats. http://www.physorg.com/news164376333.html Medicine & Health Tue, 16 Jun 2009 13:05:49 EST news164376333 Investigators at the Burnham Institute for Medical Research (Burnham) have developed a protocol to rapidly differentiate human embryonic stem cells (hESCs) into neural progenitor cells that may be ideal for transplantation. The research, conducted by Alexei Terskikh, Ph.D., and colleagues, outlines a method to create these committed neural precursor cells (C-NPCs) that is replicable, does not produce mutations in the cells and could be useful for clinical applications. The research was published on March 13 in the journal Cell Death and Differentiation. http://www.physorg.com/news158850679.html Medicine & Health Mon, 13 Apr 2009 14:13:25 EST news158850679 Biologists at the University of Leicester have published results of a new study into plant sex - and discovered that a particular gene switches on 'the essence of male'. http://www.physorg.com/news156760544.html Biology Fri, 20 Mar 2009 09:36:19 EST news156760544 Research using a mouse model of human leukemia has provided critical insight into the genetic factors related to the generation and maintenance of myeloid leukemia stem cells. The study, published by Cell Press in the February 6th issue of the journal Cell Stem Cell, is likely to have a profound impact on the future design of therapeutic approaches targeted against cancer stem cells. http://www.physorg.com/news153059231.html Biology Thu, 05 Feb 2009 12:27:42 EST news153059231 After identifying an apparent population of cancer stem cells for neuroblastoma, researchers successfully used a reprogrammed herpes virus to block tumor formation in mice by targeting and killing the cells. http://www.physorg.com/news151737767.html Medicine & Health Wed, 21 Jan 2009 05:23:22 EST news151737767 For the first time, scientists at Children's National Medical Center have successfully identified a key developmental program for the amygdala -the part of the limbic system that impacts how the brain creates emotional memories and responses. http://www.physorg.com/news151055259.html Medicine & Health Tue, 13 Jan 2009 07:47:39 EST news151055259