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<title>PHYSorg.com: PHYSorg news tagged with: senescent cells</title>
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     <title>Cellular senescence a double-edged sword</title>
   	 <description>Scientists have identified a molecular cause behind the ravages of old age and in doing so have also shown how a natural process for fighting cancer in younger persons can actually promote cancer in older individuals. Cellular senescence, the process by which biological cells stop dividing in response to stress or damage to their DNA, was shown to trigger the secretion of proteins that cause inflammation in neighboring cells and tissue. Inflammation is linked to almost every major disease associated with aging, including many cancers.</description>
     <link>http://www.physorg.com/news147538776.html</link>
	 <category>Biology</category>
	 <pubDate>Wed, 03 Dec 2008 14:59:36 EST</pubDate>
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     <title>Escape cancer, but age sooner? The dark side of the tumor suppressing process</title>
   	 <description>Cells shut down and stop dividing when their DNA is damaged, in a process known as cellular senescence, so as to prevent damaged DNA from leading to unregulated cell division and therefore cancer. However, a new study, published in this week's issue of PLoS Biology, has found that when these cells shut down they also spew proteins into their surrounding environment. This causes inflammation and sets up conditions that support the development of age-related diseases including, ironically, cancer. The new research includes the first comprehensive molecular description of a paradoxical process that prevents cancer in younger people, but promotes age-related cancers and other maladies later in life.</description>
     <link>http://www.physorg.com/news147422865.html</link>
	 <category>Biology</category>
	 <pubDate>Tue, 02 Dec 2008 06:47:45 EST</pubDate>
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     <title>Senescence in liver cells can provoke a beneficial immune reaction</title>
   	 <description>Although post-reproductive life in humans is often associated with decline and a loss of powers, an analogous state in certain cells -- called senescence -- is proving to be one of ironic potency.  Scientists at Cold Spring Harbor Laboratory (CSHL) today reported that a particular class of senescent liver cells orchestrates a sequence of events in living mice that can limit fibrosis, a natural response of the liver to acute damage.</description>
     <link>http://www.physorg.com/news138541727.html</link>
	 <category>Medicine &amp; Health</category>
	 <pubDate>Thu, 21 Aug 2008 12:48:47 EST</pubDate>
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