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Protein misprediction uncovered by new technique

Biology /

created Aug 27, 2008 | popularity not rated yet | comments 0

A new bioinformatics tool is capable of identifying and correcting abnormal, incomplete and mispredicted protein annotations in public databases. The MisPred tool, described today in the open access journal BMC Bioinformatics, curren ...


Researchers discover switch that causes the body to produce cancerous cells

Medicine & Health / Cancer

created Sep 04, 2009 | popularity 5 / 5 (1) | comments 1

A team of Syracuse University researchers discovered a second molecular switch within the Mixed Lineage Leukemia protein complex that they believe could be exploited to prevent the overproduction of abnormal cells that are ...


Study suggests new approach to common cause of blindness

Medicine & Health / Research

created Jun 14, 2009 | popularity 5 / 5 (4) | comments 0

Researchers at the University of North Carolina at Chapel Hill School of Medicine in collaboration with lead investigators at the University of Kentucky have identified a new target for the diagnosis and treatment of age-related ...


Researchers find new piece of BSE puzzle

Medicine & Health / Diseases

created Nov 20, 2009 | popularity not rated yet | comments 0

A new treatment route for bovine spongiform encephalopathy (BSE) and its human form Creutzfeldt Jakob disease (CJD) could be a step closer based on new results from scientists at the University of Leeds. The team has found ...


Modification of mutant huntingtin protein increases its clearance from brain cells

Medicine & Health / Research

created Apr 02, 2009 | popularity 5 / 5 (2) | comments 0

A new study has identified a potential strategy for removing the abnormal protein that causes Huntington's disease (HD) from brain cells, which could slow the progression of the devastating neurological disorder. In the ...


What drove the cow mad? Lessons from a tiny fish

Biology / Cell & Microbiology

created Mar 10, 2009 | popularity 4.3 / 5 (3) | comments 0

For over twenty years, scientists have known that a normal protein in the brain, PrP, or prion protein, can turn harmful and cause deadly illnesses like Creutzfeldt-Jakob disease (CJD) in humans, and bovine spongiform encephalopathy ...


Afib triggered by a cell that resembles a pigment-producing skin cell

Medicine & Health / Research

created Oct 12, 2009 | popularity not rated yet | comments 0

The source and mechanisms underlying the abnormal heart beats that initiate atrial fibrillation (Afib), the most common type of abnormal heart beat, have not been well determined. However, a group of researchers at the University ...


Bone-cell control of energy generation is regulated by the protein Atf4

Medicine & Health / Research

created Aug 10, 2009 | popularity not rated yet | comments 0

Bone cells known as osteoblasts were recently shown to have a role in controlling the biochemical reactions that generate energy via secretion of the molecule osteocalcin. Gerard Karsenty and colleagues, at Columbia University ...


Researchers identify gene associated with muscular dystrophy-related vision problems

Medicine & Health / Genetics

created Apr 21, 2009 | popularity not rated yet | comments 0

Skeletal muscle disease and vision deficits might seem unrelated, but a frog model of muscular dystrophy shows it is not such a leap.


Johns Hopkins neuroscientists discover a critical early step of memory formation

Medicine & Health / Research

created Sep 15, 2008 | popularity 5 / 5 (7) | comments 0

Researchers at the Johns Hopkins University School of Medicine report in the July issue of Neuron how nerve cells in the brain ensure that Arc, a protein critical for memory formation, is made instantly after nerve stimul ...


Researchers identify new function of protein in cellular respiration

Biology /

created Jan 28, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Virginia Commonwealth University researchers have found that the protein Stat3 plays a key role in regulating mitochondria, the energy-producing machines of cells. This discovery could one day lead to the ...


Researchers discover new glucose-regulating protein linked with diabetes

Chemistry / Biochemistry

created May 28, 2009 | popularity 5 / 5 (1) | comments 0

Researchers at the University of California, San Francisco, and collaborators at Harvard Medical School have linked a specialized protein in human muscles to the process that clears glucose out of the bloodstream, shedding ...


Mystery solved: Tiny protein-activator responsible for brain cell damage in Huntington disease

Medicine & Health / Research

created Jun 04, 2009 | popularity 5 / 5 (10) | comments 0

Johns Hopkins brain scientists have figured out why a faulty protein accumulates in cells everywhere in the bodies of people with Huntington's disease (HD), but only kills cells in the part of the brain that controls movement, ...


The heart disease mutation carried by 60 million

Medicine & Health / Genetics

created Jan 18, 2009 | popularity 4.5 / 5 (2) | comments 0

Heart disease is the number one killer in the world and India carries more than its share of this burden. Moreover, the problem is set to rise: it is predicted that by 2010 India's population will suffer approximately 60% ...


A rare case of collagenous colitis presenting as protein-losing enteropathy

Medicine & Health / Diseases

created Nov 03, 2008 | popularity 3 / 5 (1) | comments 0

Since the first report in 1976, collagenous colitis has been associated with a variety of conditions, including use of non-steroidal anti-inflammatory drugs and proton pump inhibitors. This condition is characterized by chronic ...