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Scientists uncover new class of non-protein coding genes in mammals with key functions

Scientists uncover new class of non-protein coding genes in mammals with key functions

Biology /

created Feb 01, 2009 | popularity 5 / 5 (6) | comments 0

A research team at the Broad Institute of Harvard and MIT and Beth Israel Deaconess Medical Center has uncovered a vast new class of previously unrecognized mammalian genes that do not encode proteins, but ...


LincRNAs serve as genetic air-traffic controllers

Medicine & Health / Genetics

created Jul 14, 2009 | popularity not rated yet | comments 0

Earlier this year, a scientific team from Beth Israel Deaconess Medical Center (BIDMC) and the Broad Institute identified a class of RNA genes known as large intervening non-coding RNAs or "lincRNAs," a discovery that has ...


Researchers exploit genetic 'co-dependence' to kill treatment-resistant tumor cells

Revealing cancers' weak spots: Researchers exploit genetic 'co-dependence' to kill treatment-resistant tumor cells

Medicine & Health / Cancer

created Oct 20, 2009 | popularity 5 / 5 (1) | comments 1

(PhysOrg.com) -- Cancer cells fueled by the mutant KRAS oncogene, which makes them notoriously difficult to treat, can be killed by blocking a more vulnerable genetic partner of KRAS, report scientists at ...


Researchers reveal six new genome sequences and fundamental insights to the Candida fungus family

Researchers reveal six new genome sequences and fundamental insights to the Candida fungus family

Biology / Cell & Microbiology

created May 25, 2009 | popularity 4.5 / 5 (2) | comments 0

An international research collaboration coordinated by UCD (University College Dublin) researchers and involving scientists at 21 institutes including the genome sequencing centres in the Wellcome Trust Sanger ...


New broad-spectrum vaccine to prevent cervical cancer induces strong responses in animals

Medicine & Health / Cancer

created May 26, 2009 | popularity 1 / 5 (1) | comments 0

Mice and rabbits immunized with a multimeric-L2 protein vaccine had robust antibody responses and were protected from infection when exposed to human papillomavirus (HPV) type 16 four months after vaccination, according to ...


New method takes aim at aggressive cancer cells

New method takes aim at aggressive cancer cells

Medicine & Health / Cancer

created Aug 13, 2009 | popularity 5 / 5 (2) | comments 1

A multi-institutional team of Boston-area researchers has discovered a chemical that works in mice to kill the rare but aggressive cells within breast cancers that have the ability to seed new tumors.


Researchers Genetically Link Lou Gehrig's Disease in Humans to Dog Disease

Medicine & Health / Genetics

created Jan 22, 2009 | popularity 5 / 5 (3) | comments 0

(PhysOrg.com) -- An incurable, paralyzing disease in humans is now genetically linked to a similar disease in dogs. Researchers from the University of Missouri and the Broad Institute have found that the genetic mutation ...


Scientists decipher the 3-D structure of the human genome

Scientists decipher the 3-D structure of the human genome

Medicine & Health / Genetics

created Oct 08, 2009 | popularity 5 / 5 (16) | comments 1

(PhysOrg.com) -- Scientists have deciphered the three-dimensional structure of the human genome, paving the way for new insights into genomic function and expanding our understanding of how cellular DNA folds ...


Scientists identify human monoclonal antibodies effective against bird and seasonal flu viruses

Biology /

created Feb 22, 2009 | popularity 5 / 5 (7) | comments 1

Researchers at the Dana-Farber Cancer Institute, Burnham Institute for Medical Research and the Centers for Disease Control and Prevention have reported the identification of human monoclonal antibodies (mAb) that neutralize ...


Genomic research shows Indians descended from two groups

Genomic research shows Indians descended from two groups

Medicine & Health / Genetics

created Sep 23, 2009 | popularity 4.3 / 5 (18) | comments 1

(PhysOrg.com) -- In a study published in the September 24th issue of Nature, an international team describes how they harnessed modern genomic technology to explore the ancient history of India, the world' ...


Researchers 'notch' a victory toward new kind of cancer drug

Medicine & Health / Cancer

created Nov 11, 2009 | popularity 4 / 5 (4) | comments 1

(PhysOrg.com) -- Scientists have devised an innovative way to disarm a key protein considered to be "undruggable," meaning that all previous efforts to develop a drug against it have failed. Their discovery, published in ...


Our faces, not just our ears 'hear' speech: study

Medicine & Health / Psychology & Psychiatry

created Jan 20, 2009 | popularity 3 / 5 (5) | comments 1

(PhysOrg.com) -- A McGill-led study has found that the perception of speech sounds is modified by stretching facial skin in different directions. Different patterns of skin stretch affect how subjects perceive different words.


Researchers find new molecule to block ‘Hedgehog’ signaling in cancer, development

Biology /

created Jan 19, 2009 | popularity 5 / 5 (2) | comments 0

(PhysOrg.com) -- Researchers have achieved a feat drug developers had thought difficult, if not impossible, discovering a compound that blocks the functioning of a key developmental protein by binding to an “undruggable” ...


Genome-wide study of autism published in Nature

Genome-wide study of autism published in Nature

Medicine & Health / Genetics

created Oct 07, 2009 | popularity 4.8 / 5 (6) | comments 0

(PhysOrg.com) -- In one of the first studies of its kind, an international team of researchers has uncovered a single-letter change in the genetic code that is associated with autism. The finding, published ...


Large-scale study probes how cells fight pathogens

Large-scale study probes how cells fight pathogens

Medicine & Health / Research

created Sep 03, 2009 | popularity 4 / 5 (4) | comments 0

(PhysOrg.com) -- Scientists have deciphered a key molecular circuit that enables the body to distinguish viruses from bacteria and other microbes, providing a deep view of how immune cells in mammals fend ...