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Search results for cell signaling
United we stand; divided we fall
Jul 15, 2009 |
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In the July 15th issue of G&D, Dr. Roberto Kolter (Harvard Medical School) and colleagues make the unprecedented observation of paracrine signaling during Bacillus subtilis biofilm formation.
Protein that promotes cancer cell growth identified
Jul 24, 2009 |
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Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer ...
Elevated lymphotoxin expression in liver leads to chronic hepatitis and causes HCC
Oct 05, 2009 |
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A recent study maps the pathway that leads from infection with Hepatitis B and C virus (HBV and HCV) to chronic hepatitis and liver cancer and proposes a new therapeutic strategy for treating liver diseases with chronic inflammation. ...
Crosstalk between critical cell-signaling pathways holds clues to tumor invasion and metastasis
Nov 25, 2009 |
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Two signaling pathways essential to normal human development - the Wnt/Wingless (Wnt) and epidermal growth factor receptor (EGFR) pathways - interact in ways that can promote tumor cell invasion and metastasis, researchers ...
What makes stem cells tick?
Aug 06, 2009 |
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Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) ...
Ready for relapse: Molecule helps breast cancer cells to survive in the bone marrow
Jul 06, 2009 |
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Patients who survive an initial diagnosis of breast cancer often succumb to the disease years later when the cancer shows up in a different part of the body. Now, scientists have identified key signals that support the long ...
Researchers discover new molecular pathway for targeting cancer, disease
Jul 20, 2009 |
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(PhysOrg.com) -- A UCLA study has identified a way to turn off a key signaling pathway involved in physiological processes that can also stimulate the development of cancer and other diseases. The findings may lead to new ...
Discovery makes brain tumor cells more responsive to radiation
Dec 02, 2009 |
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Duke University Medical Center researchers have figured out how stem cells in the malignant brain cancer glioma may be better able to resist radiation therapy. And using a drug to block a particular signaling pathway in these ...
'Cross-talk' mechanism contributes to colorectal cancer
Nov 13, 2009 |
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Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have identified a molecular mechanism that allows two powerful signaling pathways to interact and begin a process leading to colorectal ...
Targeting brain cancer cell metabolism may provide new treatment
Dec 15, 2009 |
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Inhibiting fatty acid synthesis in brain cancer cells may offer a new option to treat about 50 percent of deadly glioblastomas that are driven by amplified signaling of the epidermal growth factor receptor (EGFR), according ...
Stopping MRSA before it becomes dangerous is possible, researchers find
Dec 03, 2009 |
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Most scientists believe that staph infections are caused by many bacterial cells that signal each other to emit toxins. The signaling process is called quorum sensing because many bacteria must be present ...
Unraveling how cells respond to low oxygen
Aug 05, 2009 |
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Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. The REDD1 protein is a critical inhibitor of the mTOR signaling pathway, ...
Plants on Steroids: Key Missing Link Discovered
Sep 08, 2009 |
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(PhysOrg.com) -- Researchers at the Carnegie Institution's Department of Plant Biology have discovered a key missing link in the so-called signaling pathway for plant steroid hormones (brassinosteroids). Many important signaling ...
DNA-damaged cells communicate with neighbors to let them know they're in trouble
Jul 13, 2009 |
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When cells experiencing DNA damage fail to repair themselves, they send a signal to their neighbors letting them know they're in trouble. The discovery, which shows that a process dubbed the DDR (DNA Damage Response) also ...
Trio of signals converge to induce liver and pancreas cell development in the embryo
Jun 26, 2009 |
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(PhysOrg.com) -- Understanding the molecular signals that guide early cells in the embryo to develop into different organs provides insight into ways that tissues regenerate and how stem cells can be used ...
